ANISOTROPINE METHYLBROMIDE
- CAS No.
- 80-50-2
- Chemical Name:
- ANISOTROPINE METHYLBROMIDE
- Synonyms
- Vapin;C06830;valpin;endo-id;Valpin 50;endo-omid;lytispasm;Octatropine;Anisotropinmethylbromid;Octatropine metylbromide
- CBNumber:
- CB0341288
- Molecular Formula:
- C17H32NO2.Br
- Molecular Weight:
- 362.35
- MDL Number:
- MFCD00083234
- MOL File:
- 80-50-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Anisotropine methyl bromide | A5181 | 5g | $146 |
| Anisotropine Methylbromide | TRC-A673960-500MG | 500mg | $427 |
| Anisotropine Methylbromide | TRC-A673960-1G | 1g | $692 |
| Anisotropine Methylbromide | TRC-A673960-100MG | 100mg | $152 |
| Anisotropine bromide 98.0% | CS-0013173 | 5mg | $39 |
| More product size | |||
| Melting point | 329° |
|---|---|
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | 62M960DHIL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H400 |
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
| Hazard Codes | Xn,N |
| Risk Statements | 20/21/22-50/53 |
| Safety Statements | 36-61-60 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | YM3710000 |
| HazardClass | 9 |
| Hazardous Substances Data | 80-50-2(Hazardous Substances Data) |
| Limited Quantities | 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
ANISOTROPINE METHYLBROMIDE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A5181 | Anisotropine methyl bromide | 80-50-2 | 5g | $146 | 2026-04-30 | Buy |
| TRC | TRC-A673960-500MG | Anisotropine Methylbromide | 80-50-2 | 500mg | $427 | 2026-06-03 | Buy |
| TRC | TRC-A673960-1G | Anisotropine Methylbromide | 80-50-2 | 1g | $692 | 2026-06-03 | Buy |
| TRC | TRC-A673960-100MG | Anisotropine Methylbromide | 80-50-2 | 100mg | $152 | 2026-06-03 | Buy |
| ChemScene | CS-0013173 | Anisotropine bromide 98.0% | 80-50-2 | 5mg | $39 | 2026-06-04 | Buy |
ANISOTROPINE METHYLBROMIDE Chemical Properties,Uses,Production
Originator
Valpin,Endo (Du Pont),US,1963
Uses
Anisotropine Methylbromide is a antichloindergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion. Anisotropine Methylbromide was found to be potentially useful in the treatment of duodenal ulcer disease.
Definition
ChEBI: A quaternary ammonium salt resulting from the reaction of the amino group of anisotropine with methyl bromide.
Manufacturing Process
Preparation of Di-n-propyl acetyl tropine hydrochloride: Tropine (11.12 grams)
was dissolved in 100 ml of anhydrous pyridine and to this solution was added
15.64 grams of di-n-propyl acetyl chloride. The mixture was refluxed for 6
hours. This solution was then cooled and the pyridine removed in vacuum.
The residue was dissolved in chloroform. The chloroform solution was washed
with 10% hydrochloric acid to remove the residual trace of pyridine. The
hydrochloride of the product ester is soluble in chloroform and is not extracted
from chloroform by hydrochloric acid. This is an unexpected property.
The chloroform solution of the hydrochloride was dried over anhydrous
calcium sulfate, and evaporated to dryness, leaving a semisolid residue of
product ester hydrochloride. This was recrystallized from chloroform-hexane
mixture, MP 186°C.
Preparation of the Anisotropine Methyl Bromide: To the acetone solution of the
free base was added an acetone solution, containing an excess of methyl
bromide. Within a few minutes the methobromide started to crystallize. The
mixture was allowed to stand for several hours. The crystallized solid was
filtered, and additional product was obtained by evaporation of the filtrate.
The yield was nearly quantitative. After recrystallization from acetone, the
product melted at 329°C.
brand name
Valpin (Endo).
Therapeutic Function
Anticholinergic
ANISOTROPINE METHYLBROMIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Chongqing jooe co., ltd | +86-15223382610 | info@jooe.com | China | 15950 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
