2-Chloroethoxy acetic acid
- CAS No.
- 14869-41-1
- Chemical Name:
- 2-Chloroethoxy acetic acid
- Synonyms
- 2-(2-chloroethoxy)acetic acid;CAS_14869-41-1;Chloro-PEG-CH2COOH;Chloro-PEG1-CH2COOH;2-Chloroethoxy acetic acid;2-(2-Chloroethoxy)aceticaci;2-(Chloroethoxyl)acetic acid;5-Chloro-3-oxapentanoic acid;2-(2-Chloroethoxy)acetic Acid 2;(2-Chloroethoxy)acetic acid 97%
- CBNumber:
- CB0342386
- Molecular Formula:
- C4H7ClO3
- Molecular Weight:
- 138.55
- MDL Number:
- MFCD17014832
- MOL File:
- 14869-41-1.mol
- MSDS File:
- SDS
| Melting point | 32.5-33.0 °C |
|---|---|
| Boiling point | 130 °C(Press: 3.5 Torr) |
| Density | 1.3296 g/cm3 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 3.34±0.10(Predicted) |
| form | liquid |
| color | Yellow |
| InChI | InChI=1S/C4H7ClO3/c5-1-2-8-3-4(6)7/h1-3H2,(H,6,7) |
| InChIKey | MHXJETVNZPUVEN-UHFFFAOYSA-N |
| SMILES | C(O)(=O)COCCCl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302+H312+H332-H314 |
| Precautionary statements | P260-P280-P362+P364 |
| HS Code | 2918999090 |
2-Chloroethoxy acetic acid price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C365765-1G | 2-Chloroethoxyacetic Acid | 14869-41-1 | 1g | $189 | 2026-06-03 | Buy |
| TRC | TRC-C365765-10G | 2-Chloroethoxyacetic Acid | 14869-41-1 | 10g | $1501 | 2026-06-03 | Buy |
| Usbiological | 006248 | 2-Chloroethoxyacetic Acid | 14869-41-1 | 1g | $446 | 2026-06-03 | Buy |
| Apolloscientific | OR301184 | (2-Chloroethoxy)acetic acid 95% | 14869-41-1 | 50mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR301184 | (2-Chloroethoxy)acetic acid 95% | 14869-41-1 | 1g | $78 | 2026-06-04 | Buy |
2-Chloroethoxy acetic acid Chemical Properties, Uses, Production
Chemical Properties
Light Yellow Oil
Uses
A metabolite of Bis(2-chloroethyl) Ether.
Synthesis
628-89-7
14869-41-1
The general procedure for the synthesis of 2-(2-chloroethoxy)acetic acid from 2-chloroethoxyethanol was as follows: ethylene glycol mono-2-chloroethyl ether (10 g, 0.08 mol) was mixed with a 30% aqueous hydrogen peroxide solution (22.8 g, 0.2 mol), followed by the addition of sodium sulfate dihydrate (0.53 g, 1.6 mmol) and tri-octylmethyl ammonium sulfate (0.75 g, 1.6 mmol). The reaction mixture was stirred at 90°C for 4 hours. Upon completion of the reaction, the reaction was quenched by the addition of aqueous sodium thiosulfate, and then the mixture was extracted with ethyl acetate (50 mL). The organic layers were combined, washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give an oily residue (9 g). The residue was diluted with ether and filtered to remove insoluble impurities. The filtrate was extracted by partitioning with the addition of aqueous sodium bicarbonate. The aqueous layer was washed with ether, acidified to pH 2-3 with dilute hydrochloric acid and extracted with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give 2-(2-chloroethoxy)acetic acid crude (2.14 g, 19.3% yield) as an oil.IR (neat): ν = 3410 (O-H), 1727 (C=O), 1123, 1044 cm1 .
References
[1] Tetrahedron Letters, 1996, vol. 37, # 28, p. 4837 - 4840
[2] Heterocycles, 2007, vol. 74, # C, p. 437 - 445
[3] Organic and Biomolecular Chemistry, 2016, vol. 14, # 16, p. 3950 - 3955
[4] Patent: EP1640373, 2006, A1. Location in patent: Page/Page column 21
[5] Patent: WO2008/75152, 2008, A1. Location in patent: Page/Page column 40-41
2-Chloroethoxy acetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Milestone Chemical Wuxi Co.,Ltd | 18068271528 | 1917265470@qq.com | China | 72 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai Hao Yun Chemical Science Co.,Ltd. | 021-68367562 | sales@haoyunchem.com | China | 493 | 55 |
View Latest Price from 2-Chloroethoxy acetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-19 | 2-CHLOROETHOXY ACETIC ACID
14869-41-1
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2019-07-06 | 2-CHLOROETHOXY ACETIC ACID
14869-41-1
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 2-CHLOROETHOXY ACETIC ACID
14869-41-1
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 2-CHLOROETHOXY ACETIC ACID
14869-41-1
- $1.00
- 98%
- Career Henan Chemical Co
