ChemicalBook >> CAS DataBase List >>PCUHBNWYHLQSBO-HQRMLTQVSA-N
PCUHBNWYHLQSBO-HQRMLTQVSA-N
- CAS No.
- 120205-58-5
- Chemical Name:
- PCUHBNWYHLQSBO-HQRMLTQVSA-N
- Synonyms
- Monomethyl auristatin E intermediate-9;PCUHBNWYHLQSBO-HQRMLTQVSA-N;(3R,4S,5S)-tert-butyl 4-(((benzyloxy)carbonyl)(methyl)amino)-3-methoxy-5-methylheptanoate
- CBNumber:
- CB03425486
- Molecular Formula:
- C22H35NO5
- Molecular Weight:
- 393.517
- MDL Number:
- MOL File:
- 120205-58-5.mol
Last updated:2026-05-27 17:41:02
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
PCUHBNWYHLQSBO-HQRMLTQVSA-N price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA02AORT | Monomethyl auristatin E intermediate-9 98% | 120205-58-5 | 10mg | $40 | 2026-06-02 | Buy |
| Arctom | HY-78903 | Monomethyl auristatin E intermediate-9 | 120205-58-5 | 5mg | $32 | 2026-05-26 | Buy |
| Arctom | HY-78903 | Monomethyl auristatin E intermediate-9 | 120205-58-5 | 10mg | $48 | 2026-05-26 | Buy |
PCUHBNWYHLQSBO-HQRMLTQVSA-N Chemical Properties, Uses, Production
Uses
Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
References
[1] Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87. DOI:10.1158/0008-5472.CAN-14-1931
PCUHBNWYHLQSBO-HQRMLTQVSA-N Preparation Products And Raw materials
Raw materials
Preparation Products
PCUHBNWYHLQSBO-HQRMLTQVSA-N Suppliers
Global Suppliers ( 2)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9985 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Xingui Biotechnology Co., Ltd. | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 58 |
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120205-58-5
