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CBZ-L-ALANINOL

CAS No.
66674-16-6
Chemical Name:
CBZ-L-ALANINOL
Synonyms
Z-ALA-OL;Z-ALANINOL;Z-L-Ala-ol;Z-L-ALANINOL;Cbz-L-Ala-OL;CBZ-L-ALANINOL;N-Z-L-ALANINOL;Z-L-alaninol≥ 99% (HPLC);N-CARBOBENZOXY-L-ALANINOL;N-Carbobenzyloxy-L-alaninol
CBNumber:
CB0351605
Molecular Formula:
C11H15NO3
Molecular Weight:
209.24
MDL Number:
MFCD00672530
MOL File:
66674-16-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:17
Product description Number Pack Size Price
N-Z-L-Alaninol 98% 543217 5g $163
N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) C2629 1g $22
N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) C2629 5g $35
Z-L-alaninol 260735 2g $333
(S)-Benzyl(1-Hydroxypropan-2-yl)carbamate B194030 1g $75
More product size

CBZ-L-ALANINOL Properties

Melting point 81-84 °C (lit.)
Boiling point 375.2±35.0 °C(Predicted)
Density 1.149±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in ethanol.
pka 11.90±0.46(Predicted)
form powder to crystal
color White to Almost white
optical activity [α]20/D 8.0, c = 2% in ethanol
Major Application peptide synthesis
InChI 1S/C11H15NO3/c1-9(7-13)12-11(14)15-8-10-5-3-2-4-6-10/h2-6,9,13H,7-8H2,1H3,(H,12,14)/t9-/m0/s1
InChIKey AFPHMHSLDRPUSM-VIFPVBQESA-N
SMILES C[C@@H](CO)NC(=O)OCc1ccccc1
CAS DataBase Reference 66674-16-6(CAS DataBase Reference)
UNSPSC Code 12352209

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
PPE Eyeshields, Gloves
Safety Statements  24/25
WGK Germany  3
HS Code  29221990
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

CBZ-L-ALANINOL price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 543217 N-Z-L-Alaninol 98% 66674-16-6 5g $163 2023-01-07 Buy
TCI Chemical C2629 N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) 66674-16-6 1g $22 2026-03-19 Buy
TCI Chemical C2629 N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) 66674-16-6 5g $35 2026-03-19 Buy
Usbiological 260735 Z-L-alaninol 66674-16-6 2g $333 2021-12-16 Buy
TRC B194030 (S)-Benzyl(1-Hydroxypropan-2-yl)carbamate 66674-16-6 1g $75 2021-12-16 Buy
Product number Packaging Price Buy
543217 5g $163 Buy
C2629 1g $22 Buy
C2629 5g $35 Buy
260735 2g $333 Buy
B194030 1g $75 Buy

CBZ-L-ALANINOL Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

N-Benzyloxycarbonyl-L-alaninol is used as an important organic intermediate. It is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

N-Carbobenzyloxy-L-alanine

1142-20-7

(S)-benzyl (1-hydroxypropan-2-yl)carbamate

6429-44-3

GENERAL METHODS: To a solution of benzyloxycarbonyl-L-alanine (10 mmol) in tetrahydrofuran (THF, 10 mL) was added N,N-diisopropylethylamine (DIPEA, 11 mmol, 1.42 mL) and a solution of 50% propylphosphonic anhydride (T3P) in ethyl acetate (EtOAc) (20 mmol, 6.36 mL) at 0°C with stirring for about 10 minutes. Then sodium borohydride (NaBH4) aqueous solution (10 mmol, 388 mg, dissolved in 0.3 mL of water) was slowly added to the reaction mixture at the same temperature, and the progress of the reaction was monitored by thin-layer chromatography (TLC) until the reaction was completed. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure, and the crude product was dissolved in ethyl acetate (EtOAc), and the organic phase was washed sequentially with 5% aqueous citric acid (10 mL x 2), 5% aqueous sodium carbonate (Na2CO3) (10 mL x 2), water and saturated saline. The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and the solvent was evaporated under reduced pressure to obtain the target compound.

References

[1] Antimicrobial Agents and Chemotherapy, 2017, vol. 61, # 3,
[2] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[3] Tetrahedron Letters, 1992, vol. 33, # 30, p. 4257 - 4260
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1975 - 1980
[5] Tetrahedron: Asymmetry, 1992, vol. 3, # 11, p. 1401 - 1410

CBZ-L-ALANINOL Preparation Products And Raw materials

Global( 171)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+8618382028708 ni@enlaibio.com China 1098 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9541 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58

View Lastest Price from CBZ-L-ALANINOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cbz-L-Ala-OL pictures 2026-04-24 Cbz-L-Ala-OL
66674-16-6
US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
CBZ-L-ALANINOL pictures 2025-04-04 CBZ-L-ALANINOL
66674-16-6
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
CBZ-L-ALANINOL pictures 2021-08-12 CBZ-L-ALANINOL
66674-16-6
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • Cbz-L-Ala-OL pictures
  • Cbz-L-Ala-OL
    66674-16-6
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • CBZ-L-ALANINOL pictures
  • CBZ-L-ALANINOL
    66674-16-6
  • US $0.00-0.00 / KG
  • 98%
  • Henan Aochuang Chemical Co.,Ltd.
  • CBZ-L-ALANINOL pictures
  • CBZ-L-ALANINOL
    66674-16-6
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
(S)-(2-HYDROXY-1-METHYLETHYL)CARBAMIC ACID BENZYL ESTER (S)-(-)-2-(Z-AMINO)-1-PROPANOL N-CARBOBENZOXY-L-ALANINOL N-Z-L-ALANINOL Z-ALA-OL Z-ALANINOL Z-L-ALANINOL CBZ-L-ALANINOL (-)-N-[(S)-2-Hydroxy-1-methylethyl]carbamic acid benzyl ester (S)-2-(Benzyloxycarbonylamino)-1-propanol N-[(S)-1-(Hydroxymethyl)ethyl]carbamic acid benzyl ester N-[(S)-2-Hydroxy-1-methylethyl]carbamic acid benzyl ester N-Benzyloxycarbonyl-L-alaninol (S)-benzyl 1-hydroxypropan-2-ylcarbamate N-Cbz-L-alaninol (S)-N-Cbz-2-Amino-1-propanol Cbz-L-Ala-OL N-Carbobenzoxy-L-alaninol Z-L-alaninol≥ 99% (HPLC) Z-L-Ala-ol N-[(S)-2-Hydroxy-1-methylethyl]carbamic Acid Phenylmethyl Ester N-Carbobenzoxy-L-alaninol > Carbamic acid, N-[(1S)-2-hydroxy-1-methylethyl]-, phenylmethyl ester (S)-N-Benzyloxycarbonyl-2-Amino-1-propanol (S)-N-Cbz-2-Amino-1-propanol N-Carbobenzyloxy-L-alaninol benzyl N-[(1S)-2-hydroxy-1-methyl-ethyl]carbamate Benzyl [(2S)-1-hydroxy-2-propanyl]carbamate N-Z-L-Alaninol 66674-16-6 C6H5CH2O2CNHCHCH3CH2OH C6H5CH2O2CNHCHCH3CH2 Peptide Synthesis Specialty Synthesis Amino Alcohols Amino Acid Derivatives