CBZ-L-ALANINOL
- CAS No.
- 66674-16-6
- Chemical Name:
- CBZ-L-ALANINOL
- Synonyms
- Z-ALA-OL;Z-ALANINOL;Z-L-Ala-ol;Z-L-ALANINOL;Cbz-L-Ala-OL;CBZ-L-ALANINOL;N-Z-L-ALANINOL;Z-L-alaninol≥ 99% (HPLC);N-CARBOBENZOXY-L-ALANINOL;N-Carbobenzyloxy-L-alaninol
- CBNumber:
- CB0351605
- Molecular Formula:
- C11H15NO3
- Molecular Weight:
- 209.24
- MDL Number:
- MFCD00672530
- MOL File:
- 66674-16-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| N-Z-L-Alaninol 98% | 543217 | 5g | $163 |
| N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) | C2629 | 1g | $22 |
| N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) | C2629 | 5g | $35 |
| Z-L-alaninol | 260735 | 2g | $333 |
| (S)-Benzyl(1-Hydroxypropan-2-yl)carbamate | B194030 | 1g | $75 |
| More product size | |||
| Melting point | 81-84 °C (lit.) |
|---|---|
| Boiling point | 375.2±35.0 °C(Predicted) |
| Density | 1.149±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in ethanol. |
| pka | 11.90±0.46(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| optical activity | [α]20/D 8.0, c = 2% in ethanol |
| Major Application | peptide synthesis |
| InChI | 1S/C11H15NO3/c1-9(7-13)12-11(14)15-8-10-5-3-2-4-6-10/h2-6,9,13H,7-8H2,1H3,(H,12,14)/t9-/m0/s1 |
| InChIKey | AFPHMHSLDRPUSM-VIFPVBQESA-N |
| SMILES | C[C@@H](CO)NC(=O)OCc1ccccc1 |
| CAS DataBase Reference | 66674-16-6(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29221990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
CBZ-L-ALANINOL price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 543217 | N-Z-L-Alaninol 98% | 66674-16-6 | 5g | $163 | 2023-01-07 | Buy |
| TCI Chemical | C2629 | N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) | 66674-16-6 | 1g | $22 | 2026-03-19 | Buy |
| TCI Chemical | C2629 | N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N) | 66674-16-6 | 5g | $35 | 2026-03-19 | Buy |
| Usbiological | 260735 | Z-L-alaninol | 66674-16-6 | 2g | $333 | 2021-12-16 | Buy |
| TRC | B194030 | (S)-Benzyl(1-Hydroxypropan-2-yl)carbamate | 66674-16-6 | 1g | $75 | 2021-12-16 | Buy |
CBZ-L-ALANINOL Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Uses
N-Benzyloxycarbonyl-L-alaninol is used as an important organic intermediate. It is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
1142-20-7
6429-44-3
GENERAL METHODS: To a solution of benzyloxycarbonyl-L-alanine (10 mmol) in tetrahydrofuran (THF, 10 mL) was added N,N-diisopropylethylamine (DIPEA, 11 mmol, 1.42 mL) and a solution of 50% propylphosphonic anhydride (T3P) in ethyl acetate (EtOAc) (20 mmol, 6.36 mL) at 0°C with stirring for about 10 minutes. Then sodium borohydride (NaBH4) aqueous solution (10 mmol, 388 mg, dissolved in 0.3 mL of water) was slowly added to the reaction mixture at the same temperature, and the progress of the reaction was monitored by thin-layer chromatography (TLC) until the reaction was completed. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure, and the crude product was dissolved in ethyl acetate (EtOAc), and the organic phase was washed sequentially with 5% aqueous citric acid (10 mL x 2), 5% aqueous sodium carbonate (Na2CO3) (10 mL x 2), water and saturated saline. The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and the solvent was evaporated under reduced pressure to obtain the target compound.
References
[1] Antimicrobial Agents and Chemotherapy, 2017, vol. 61, # 3,
[2] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[3] Tetrahedron Letters, 1992, vol. 33, # 30, p. 4257 - 4260
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1975 - 1980
[5] Tetrahedron: Asymmetry, 1992, vol. 3, # 11, p. 1401 - 1410
CBZ-L-ALANINOL Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1098 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9541 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
View Lastest Price from CBZ-L-ALANINOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-24 | Cbz-L-Ala-OL
66674-16-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd | |
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2025-04-04 | CBZ-L-ALANINOL
66674-16-6
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
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2021-08-12 | CBZ-L-ALANINOL
66674-16-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-

- Cbz-L-Ala-OL
66674-16-6
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-

- CBZ-L-ALANINOL
66674-16-6
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- CBZ-L-ALANINOL
66674-16-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd





