(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
- CAS No.
- 110859-47-7
- Chemical Name:
- (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
- Synonyms
- BUTTPARK 85\12-11;Mosapride Impurity 22;2-Aminomethyl-4-benzylmorpholine;4-Benzyl-2-(aMinoMethyl)Morpholine;4-(Benzyl)-2-morpholinemethanamine;(4-BENZYLMORPHOLIN-2-YL)METHYLAMINE;(4-Benzyl-2-Morpholinyl)MethanaMine;(4-BENZYLMORPHOLIN-2-YL) METHANAMINE;1-(4-Benzylmorpholin-2-yl)methanamine;(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
- CBNumber:
- CB0351791
- Molecular Formula:
- C12H18N2O
- Molecular Weight:
- 206.28
- MDL Number:
- MFCD02682010
- MOL File:
- 110859-47-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (4-Benzylmorpholin-2-yl)methylamine 95% | OR23186 | 250mg | $100 |
| (4-Benzylmorpholin-2-yl)methanamine 95% | AS36118 | 1g | $101 |
| (4-Benzylmorpholin-2-yl)methylamine 95% | OR23186 | 1g | $166 |
| (4-Benzylmorpholin-2-yl)methanamine 95% | AS36118 | 5g | $466 |
| (4-Benzyl-1,4-oxazinan-2-yl)methylamine | 081960 | 250.00mg | $39 |
| More product size | |||
| Boiling point | 120-122°C 0,5mm |
|---|---|
| Density | 1.076 |
| Flash point | 143℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | solid |
| pka | 9.37±0.29(Predicted) |
| Appearance | Colorless to light yellow Viscous Liquid |
| optical activity | 0.15°(C=1 g/100ml MEOH) |
| InChI | 1S/C12H18N2O/c13-8-12-10-14(6-7-15-12)9-11-4-2-1-3-5-11/h1-5,12H,6-10,13H2 |
| InChIKey | CKZVBXBEDDAEFE-UHFFFAOYSA-N |
| SMILES | NCC1OCCN(C1)CC2=CC=CC=C2 |
| CAS DataBase Reference | 110859-47-7(CAS DataBase Reference) |
| UNSPSC Code | 12352116 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H319 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39 |
| RIDADR | 2735 |
| Hazard Note | Irritant |
| HS Code | 2921199990 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral |
(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR23186 | (4-Benzylmorpholin-2-yl)methylamine 95% | 110859-47-7 | 250mg | $100 | 2026-06-04 | Buy |
| Activate Scientific | AS36118 | (4-Benzylmorpholin-2-yl)methanamine 95% | 110859-47-7 | 1g | $101 | 2026-06-04 | Buy |
| Apolloscientific | OR23186 | (4-Benzylmorpholin-2-yl)methylamine 95% | 110859-47-7 | 1g | $166 | 2026-06-04 | Buy |
| Activate Scientific | AS36118 | (4-Benzylmorpholin-2-yl)methanamine 95% | 110859-47-7 | 5g | $466 | 2026-06-04 | Buy |
| Matrix Scientific | 081960 | (4-Benzyl-1,4-oxazinan-2-yl)methylamine | 110859-47-7 | 250.00mg | $39 | 2026-05-18 | Buy |
(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Chemical Properties,Uses,Production
Synthesis
110859-48-8
110859-47-7
General procedure for the synthesis of (4-benzyl-2-morpholinyl)methanamine from 2-[[4-(benzyl)-2-morpholinyl]methyl]-1H-isoindole-1,3(2H)-dione: To a 50 mL single-necked round-bottomed flask was added 2-(4-benzylmorpholin-2-yl)methylphthalimide (1.3 g, 3.87 mmol) and hydrazine hydrate (0.38 g, 7.6 mmol) and ethanol (13 mL) was added. The mixture was heated to 80 °C and then stirred for 4 hours. After completion of the reaction, which was monitored by thin layer chromatography (TLC), the resulting solution was cooled to room temperature and filtered to separate the inorganic material. The filtrate was concentrated under vacuum, 10% sodium hydroxide solution (10 mL) was added and extracted twice with dichloromethane (20 mL). All extracted organic layers were combined, dried with anhydrous magnesium sulfate and filtered. The filtrate was concentrated under vacuum to give a solid product. The resulting solid was dried in an oven at 60 °C to give (4-benzylmorpholin-2-yl)methylamine (550 mg, 69% yield). The dried product was used directly in the subsequent reaction.
References
[1] Journal of Medicinal Chemistry, 1990, vol. 33, # 5, p. 1406 - 1413
[2] Journal of Medicinal Chemistry, 1993, vol. 36, # 10, p. 1356 - 1363
[3] Patent: WO2012/128582, 2012, A2. Location in patent: Page/Page column 110
[4] Patent: WO2007/71936, 2007, A1. Location in patent: Page/Page column 86
(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-12 | Mosapride Impurity 22 | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
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2026-03-12 | Mosapride Impurity 22 | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
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2021-08-12 | (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
110859-47-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- Mosapride Impurity 22
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-

- Mosapride Impurity 22
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-

- (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
110859-47-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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