4-FLUORO-3-METHOXYBENZOIC ACID
- CAS No.
- 82846-18-2
- Chemical Name:
- 4-FLUORO-3-METHOXYBENZOIC ACID
- Synonyms
- BUTTPARK 14\01-28;RARECHEM AL BO 0973;4-fluoro-m-anisic acid;4-Fluoro-3-methoxybenzoic;Fluoro-3-methoxy-benzoic acid;4-FLUORO-3-METHOXYBENZOIC ACID;3-METHOXY-4-FLUOROBENZOIC ACID;4-Fluoro-3-methoxybenzoicAcid>Benzoic acid, 4-fluoro-3-methoxy-;4-Fluoro-m-anisic acid, 5-Carboxy-2-fluoroanisole
- CBNumber:
- CB0396031
- Molecular Formula:
- C8H7FO3
- Molecular Weight:
- 170.14
- MDL Number:
- MFCD00272134
- MOL File:
- 82846-18-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Fluoro-3-methoxybenzoic Acid >98.0%(GC)(T) | F0681 | 1g | $28 |
| 4-Fluoro-3-methoxybenzoic Acid >98.0%(GC)(T) | F0681 | 5g | $127 |
| 4-Fluoro-3-methoxybenzoic acid | FF66821 | 50g | $150 |
| 4-Fluoro-3-methoxybenzoic acid | FF66821 | 100g | $150 |
| 4-Fluoro-3-methoxybenzoic acid 96% | PC4823 | 5g | $25 |
| More product size | |||
| Melting point | 206 °C |
|---|---|
| Boiling point | 304.8±22.0 °C(Predicted) |
| Density | 1.307±0.06 g/cm3(Predicted) |
| Flash point | >110℃ |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 4.02±0.10(Predicted) |
| form | powder to crystal |
| color | White to Yellow to Orange |
| BRN | 4178071 |
| InChIKey | LWGCZCMLPRMKIZ-UHFFFAOYSA-N |
| CAS DataBase Reference | 82846-18-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-36:37/38-22 | |||||||||
| Safety Statements | 26-36-37 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
4-FLUORO-3-METHOXYBENZOIC ACID price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0681 | 4-Fluoro-3-methoxybenzoic Acid >98.0%(GC)(T) | 82846-18-2 | 1g | $28 | 2026-04-30 | Buy |
| TCI Chemical | F0681 | 4-Fluoro-3-methoxybenzoic Acid >98.0%(GC)(T) | 82846-18-2 | 5g | $127 | 2026-04-30 | Buy |
| Biosynth | FF66821 | 4-Fluoro-3-methoxybenzoic acid | 82846-18-2 | 50g | $150 | 2026-06-04 | Buy |
| Biosynth | FF66821 | 4-Fluoro-3-methoxybenzoic acid | 82846-18-2 | 100g | $150 | 2026-06-04 | Buy |
| Apolloscientific | PC4823 | 4-Fluoro-3-methoxybenzoic acid 96% | 82846-18-2 | 5g | $25 | 2026-06-04 | Buy |
4-FLUORO-3-METHOXYBENZOIC ACID Chemical Properties,Uses,Production
Chemical Properties
White to light yellow crystal powder
Synthesis Reference(s)
Journal of Medicinal Chemistry, 33, p. 2408, 1990 DOI: 10.1021/jm00171a014
Synthesis
74385-37-8
82846-18-2
The general procedure for the synthesis of 3-methoxy-4-fluorobenzoic acid from methyl 4-fluoro-3-methoxybenzoate was as follows: methyl 4-fluoro-3-methoxybenzoate (11 g, 59.8 mmol) was dissolved in methanol (100 mL), and a solution of sodium hydroxide (9.5 g, 240 mmol) in water (20 mL) was added, and the reaction was stirred for 4 h at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give a residue. The residue was dissolved in water (100 mL) and the pH was adjusted with 1N HCl solution to 4. Subsequently, the precipitated solid was collected by filtration, washed with water (3 x 50 mL), and dried to give 3-methoxy-4-fluorobenzoic acid as a white solid (9 g, 97% yield). The product was characterized by 1H-NMR (300 MHz, DMSO-d6): δ 7.66-7.55 (m, 2H), 7.37-7.30 (m, 1H), 3.91 (s, 3H).
References
[1] Patent: WO2014/66795, 2014, A1. Location in patent: Paragraph 0175
[2] Patent: US2004/204427, 2004, A1. Location in patent: Page/Page column 42
4-FLUORO-3-METHOXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
View Lastest Price from 4-FLUORO-3-METHOXYBENZOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4-FLUORO-3-METHOXYBENZOIC ACID
82846-18-2
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-12-01 | 4-FLUORO-3-METHOXYBENZOIC ACID
82846-18-2
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-08-12 | 4-FLUORO-3-METHOXYBENZOIC ACID
82846-18-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4-FLUORO-3-METHOXYBENZOIC ACID
82846-18-2
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-FLUORO-3-METHOXYBENZOIC ACID
82846-18-2
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-FLUORO-3-METHOXYBENZOIC ACID
82846-18-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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