4,5-Imidazoledicarboxylic acid
- CAS No.
- 570-22-9
- Chemical Name:
- 4,5-Imidazoledicarboxylic acid
- Synonyms
- 1H-IMIDAZOLE-4,5-DICARBOXYLIC ACID;edicarboxyL;AKOS AUF2071;4,5-ImidazoL;AKOS BBS-00002898;IFLAB-BB F1918-0019;RARECHEM AL BO 1102;4,5-Dicarboxymidazole;4,5-Dicarboxyimidazole;4,5-Imidazoledicarboxylate
- CBNumber:
- CB0401861
- Molecular Formula:
- C5H4N2O4
- Molecular Weight:
- 156.1
- MDL Number:
- MFCD00005200
- MOL File:
- 570-22-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4,5-Imidazoledicarboxylic acid 97% | 246115 | 5g | $66.1 |
| 4,5-Imidazoledicarboxylic acid 97% | 246115 | 25g | $176 |
| 1H-Imidazole-4,5-dicarboxylic Acid >98.0%(HPLC)(T) | I0003 | 5g | $61 |
| 1H-Imidazole-4,5-dicarboxylic Acid >98.0%(HPLC)(T) | I0003 | 25g | $102 |
| 4,5-Imidazoledicarboxylic Acid | 433739 | 1g | $319 |
| More product size | |||
| Melting point | 280-285 °C (dec.) (lit.) |
|---|---|
| Boiling point | 280.29°C (rough estimate) |
| bulk density | 650-660kg/m3 |
| Density | 1,749 g/cm3 |
| refractive index | 1.4800 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | 0.5g/l |
| pka | 3.59±0.10(Predicted) |
| form | Fine Crystalline Powder |
| color | Light yellow to yellow-brown |
| PH | 3.7 (0.5g/l, H2O, 20℃) |
| Water Solubility | 0.5g/L(20 ºC) |
| BRN | 147774 |
| InChI | 1S/C5H4N2O4/c8-4(9)2-3(5(10)11)7-1-6-2/h1H,(H,6,7)(H,8,9)(H,10,11) |
| InChIKey | ZEVWQFWTGHFIDH-UHFFFAOYSA-N |
| SMILES | OC(=O)c1nc[nH]c1C(O)=O |
| CAS DataBase Reference | 570-22-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | DP9E7PEL2M |
| NIST Chemistry Reference | 4,5-Imidazole dicarboxylic acid(570-22-9) |
| EPA Substance Registry System | 1H-Imidazole-4,5-dicarboxylic acid (570-22-9) |
| UNSPSC Code | 12352106 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NI4760000 | |||||||||
| Autoignition Temperature | 430°C | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29332990 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
4,5-Imidazoledicarboxylic acid price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 246115 | 4,5-Imidazoledicarboxylic acid 97% | 570-22-9 | 5g | $66.1 | 2023-06-20 | Buy |
| Sigma-Aldrich | 246115 | 4,5-Imidazoledicarboxylic acid 97% | 570-22-9 | 25g | $176 | 2022-05-15 | Buy |
| TCI Chemical | I0003 | 1H-Imidazole-4,5-dicarboxylic Acid >98.0%(HPLC)(T) | 570-22-9 | 5g | $61 | 2026-04-30 | Buy |
| TCI Chemical | I0003 | 1H-Imidazole-4,5-dicarboxylic Acid >98.0%(HPLC)(T) | 570-22-9 | 25g | $102 | 2021-12-16 | Buy |
| Usbiological | 433739 | 4,5-Imidazoledicarboxylic Acid | 570-22-9 | 1g | $319 | 2026-06-03 | Buy |
4,5-Imidazoledicarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
light yellow to yellow-brown fine cryst. powder
Uses
4,5-Imidazoledicarboxylic acid is an imidazole used for research purposes.
Uses
4,5-Imidazoledicarboxylic Acid is an intermediate used in the synthesis of N-substituted cyclic imides with anticancer and anti-inflammatory activities. it is also used to prepare imidazolecarboxamide derivatives with cannabinoid CB2 receptor antagonistic activities.
Synthesis
5465-29-2
570-22-9
General procedure: 800 ml of concentrated sulfuric acid (80% concentration) was slowly added to 200 ml of water to form a reaction system. To this system was added 50.0 g of 2-propylbenzimidazole, followed by the slow dropwise addition of 30 mL of hydrogen peroxide to 500 mL of the reaction mixture. The reaction is exothermic and causes reflux, and the rate of titration needs to be controlled to maintain the reaction solution at a boil. After completion of the reaction, stirring was continued for 3 hours. Subsequently, 1000 mL of water was added to the reaction mixture and cooled to room temperature. The mixture was stirred for 3 hours at 0 to 5°C to promote precipitation of solids. The solid was collected by filtration and washed sequentially with water and 5% aqueous sodium sulfite solution (100 mL). The resulting solid was purified by column chromatography using water: methanol = 2:1 as eluent to give the final imidazole-4,5-dicarboxylic acid 3-lg with a melting point of 267.3 °C (simultaneous decomposition).
References
[1] Patent: CN104262260, 2016, B. Location in patent: Paragraph 0093-0095
4,5-Imidazoledicarboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Synbest Biotech(Hangzhou) Co., Ltd | 86-571-88737065 | sales@synbestech.com | CHINA | 170 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from 4,5-Imidazoledicarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4,5-Imidazoledicarboxylic acid
570-22-9
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2021-08-12 | 4,5-Imidazoledicarboxylic acid
570-22-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-13 | 4,5-Imidazoledicarboxylic acid
570-22-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4,5-Imidazoledicarboxylic acid
570-22-9
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4,5-Imidazoledicarboxylic acid
570-22-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 4,5-Imidazoledicarboxylic acid
570-22-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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