ChemicalBook >> CAS DataBase List >>Span 80

Span 80

CAS No.
1338-43-8
Chemical Name:
Span 80
Synonyms
SORBITAN MONOOLEATE;SORBITAN OLEATE;armotanmo;ionets80;sorgen40;sorbons80;glycomulo;emsorb2500;SPAN(R) 80;EmulsifierS80
CBNumber:
CB0419567
Molecular Formula:
C24H44O6
Molecular Weight:
428.6
MDL Number:
MFCD00080948
MOL File:
1338-43-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:22
Product description Number Pack Size Price
Span® 80 for synthesis 8.40123 100mL $53.5
Span? 80 non-ionic 85548 1l $249
Span® 80 for synthesis 8.40123 500mL $99.9
Span® 80 for synthesis 8.40123 1L $182
Span? 80 for GC 09569 50ml $294
More product size

Span 80 Properties

Boiling point 463.43°C (rough estimate)
Density 0.986 g/mL at 25 °C(lit.)
vapor pressure <1.4 hPa (20 °C)
refractive index n20/D 1.48(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility Practically insoluble but dispersible in water, soluble in fatty oils producing a hazy solution, miscible with alcohol.
form Viscous Liquid
color Yellow
Specific Gravity 0.986
Odor at 100.00 %. fatty oily waxy
Odor Type fatty
Viscosity 1000-2000mPa.s(20°C)
Water Solubility Soluble in ethanol at 50mg/mlMiscible with water, ethanol, isopropanol and ether. Insoluble in acetone.
Merck 13,8796
BRN 8172514
Hydrophilic-Lipophilic Balance (HLB) 4.3
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Major Application microbiology
Cosmetics Ingredients Functions SURFACTANT - EMULSIFYING
InChIKey MPZLHRXPRGLWEB-AAZCQSIUSA-N
SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O
LogP 6.014 (est)
CAS DataBase Reference 1338-43-8(CAS DataBase Reference)
FDA 21 CFR 173.75; 175.105; 73.1001
Substances Added to Food (formerly EAFUS) SORBITAN MONOOLEATE
EWG's Food Scores 1
FDA UNII 06XEA2VD56
EPA Substance Registry System Sorbitan monooleate (1338-43-8)
UNSPSC Code 12352108
NACRES NA.25

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves
Safety Statements  24/25
WGK Germany  1
RTECS  WG2932400
TSCA  TSCA listed
HS Code  34021300
Storage Class 10 - Combustible liquids
Hazardous Substances Data 1338-43-8(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: > 39800 mg/kg
NFPA 704
1
1 0

Span 80 price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.40123 Span® 80 for synthesis 1338-43-8 100mL $53.5 2026-04-30 Buy
Sigma-Aldrich 85548 Span? 80 non-ionic 1338-43-8 1l $249 2026-04-30 Buy
Sigma-Aldrich 8.40123 Span® 80 for synthesis 1338-43-8 500mL $99.9 2026-04-30 Buy
Sigma-Aldrich 8.40123 Span® 80 for synthesis 1338-43-8 1L $182 2026-04-30 Buy
Sigma-Aldrich 09569 Span? 80 for GC 1338-43-8 50ml $294 2026-04-30 Buy
Product number Packaging Price Buy
8.40123 100mL $53.5 Buy
85548 1l $249 Buy
8.40123 500mL $99.9 Buy
8.40123 1L $182 Buy
09569 50ml $294 Buy

Span 80 Chemical Properties,Uses,Production

HLB Values

HLB Values of Common Surfactants:
Span 80
Surfactants with lower HLB values (3-6) are lipophilic and are conducive to the formation of water-in-oil (W/O) emulsions; surfactants with higher HLB values (8-18) are hydrophilic and are conducive to the formation of oil-in-water (O/W) emulsions.

Description

Span 80, also known as sorbitan monooleate, is a nonionic surfactant and emulsifier. It belongs to the family of sorbitan esters. This ingredient is produced by esterifying sorbitan with oleic acid, a fatty acid in many vegetable oils. Span 80 emulsifier presents as a light yellow, viscous, oily liquid. Its solubility characteristics include insolubility in water and solubility in organic solvents. Span 80 is an emulsifier, stabilizer, and dispersant used in the food, pharmaceutical, and cosmetics industries.

Chemical Properties

Brownish-yellow, viscous liquid.

Uses

Span 80 is a low HLB surfactant suggested for use as a w/o emulsifier or as an o/w emulsifier for use in cosmetic formulations, oil field chemicals, plastics, household products, coatings and textiles.

Application

Span 80 is a low HLB nonionic emulsifier, often used in combination with tween 80. It is mainly used in the following aspects:
(1) As a food additive. It can be added to desserts, bread, ice cream and beverages to enhance the taste of food, improve stability and extend shelf life.
(2) As a cosmetic emulsifier, thickener and surfactant, it is commonly found in sunscreen, face cream, essence, lotion and other products.
(3) As a pharmaceutical adjuvant. It can be used for the encapsulation and storage of pharmaceutical active ingredients (such as phenols, vitamins and other various antioxidant-rich molecules), and can also be used as an emulsifier, thickener and stabilizer in compound preparations.
(4) Fiber lubricant and softener in the textile industry.

Definition

ChEBI: Sorbitan monooleate is a fatty acid ester.

Safety Profile

A skin irritant. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Global( 645)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangdong Huana Chemistry Co.,Ltd.
+862036293412 +8614749365990 sales@huanachemical.com CHINA 15 58
Aurora Industry Co., Ltd.
+86-13591747876 +86-13591747876; alex1_auco@126.com China 300 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7245 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+8617392709771 1097@dideu.com China 3996 58
Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850 info@fortunachem.com China 5974 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-18712993135 sales01@tairunfaz.com China 8051 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58

Related articles

View Lastest Price from Span 80 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Span 80 pictures 2026-05-01 Span 80
1338-43-8
0.99 RongNa Biotechnology Co.,Ltd
Span 80 pictures 2026-04-30 Span 80
1338-43-8
US $0.00-0.00 / kg 0.001kg 99.99% 200000t Anhuyan (Hainan) Biotechnology Co., LTD
Span 80 pictures 2026-04-30 Span 80
1338-43-8
US $0.00-0.00 / kg 1kg 99% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
  • Span 80 pictures
  • Span 80
    1338-43-8
  • 0.99
  • RongNa Biotechnology Co.,Ltd
  • Span 80 pictures
  • Span 80
    1338-43-8
  • US $0.00-0.00 / kg
  • 99.99%
  • Anhuyan (Hainan) Biotechnology Co., LTD
  • Span 80 pictures
  • Span 80
    1338-43-8
  • US $0.00-0.00 / kg
  • 99%
  • WUHAN FORTUNA CHEMICAL CO., LTD
armotanmo emsorb2500 EmulsifierS80 glycomulo ionets80 sorbons80 sorgen40 Arlacel 80 Sorbitan Monooleate (R)-1-((2S,3R,4S)-3,4-Dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl oleate Oleic acid coMpound with (2R,3R,4S)-2-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol (1:1) SPAN(R) 80, NONIONIC SURFACTANT -1,2-dihydroxyethyl) Oleic acid compound with (2R,3R,4S) tetrahydrofuran-3,4-diol (1:1) SPAN 80 SPAN NO 80 SPAN(TM) 80 sorbitan (z)-mono-9-octadecenoate EMALEX SPO-100 ARLACEL 80 SPAN 80 span 80 Sorbitan monooleae Sorbitan Oleate(Span 80) ionets-80 liposorbo liposorbo-20 ml33f ml55f mo33f mono-9-octadecenoate,(z)-sorbita mono-9-octadecenoate,(Z)-Sorbitan monodehydrosorbitolmonooleate montan80 nikkolso10 nikkolso15 nikkolso-15 nikkolso-30 nonionop80r o250 radiasurf7155 sorbesterp17 SorbitanmonooleateS80 sorbitanmonooleicacidester sorbitano SPAN(R) 80, FOR GC SPAN (R) 80 HLB-VALUE 4.3 Sorbitan, mono-(9Z)-9-octadecenoate Sorbitanoleat Span 80 (=Sorbitan Monooleate) Sorbitan monooleate, Span(R) 80 Lonzest(R) SMO Lonzest(R) SMO-EG Sorbitan Monooleate explosive grade 1,4-Anhydro-6-o-[(9Z)-octadec-9-enoyl]-D-glucitol Span 80,Sorbitane monooleate Sorbitan, mono-9-octadecenoate, (Z)- NSC-406239 Span 80