2,5-Dibromoterephthalic acid
- CAS No.
- 13731-82-3
- Chemical Name:
- 2,5-Dibromoterephthalic acid
- Synonyms
- JACS-13731-82-3;2,5-Dibromoterephtha;2,5-Dibromterephthalsure;2,5-DibromoterephthalicAci;2,5-DIBROMOTEREPHTALIC ACID;2,5-DIBROMOTEREPHTHALIC ACID;2,5-dibromotetrephthalic acid;2,5-DibromoterephthalicAcid>2,5-dibromo-4-benzenedicarboxylicacid;2,5-Dibromo-1,4-PhenyldicarboxylicAcid
- CBNumber:
- CB0423720
- Molecular Formula:
- C8H4Br2O4
- Molecular Weight:
- 323.92
- MDL Number:
- MFCD00204593
- MOL File:
- 13731-82-3.mol
| Product description | Number | Pack Size | Price |
| 2,5-Dibromoterephthalic Acid >98.0%(GC)(T) | D3994 | 5g | $70 |
| 2,5-Dibromoterephthalic Acid >98.0%(GC)(T) | D3994 | 25g | $275 |
| 2,5-Dibromoterephthalic Acid | D426195 | 1g | $55 |
| 2,5-Dibromoterephthalic Acid | D426195 | 2.5g | $65 |
| 2,5-Dibromoterephthalic acid | FD70813 | 25g | $55 |
| More product size | |||
| Melting point | 320-325°C |
|---|---|
| Boiling point | 445.0±45.0 °C(Predicted) |
| Density | 2.205±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 1.75±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| InChIKey | VUTICWRXMKBOSF-UHFFFAOYSA-N |
| CAS DataBase Reference | 13731-82-3(CAS DataBase Reference) |
| FDA UNII | 63JN659KM5 |
| EPA Substance Registry System | 1,4-Benzenedicarboxylic acid, 2,5-dibromo- (13731-82-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2917399590 | |||||||||
| NFPA 704 |
|
2,5-Dibromoterephthalic acid price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D3994 | 2,5-Dibromoterephthalic Acid >98.0%(GC)(T) | 13731-82-3 | 5g | $70 | 2025-07-31 | Buy |
| TCI Chemical | D3994 | 2,5-Dibromoterephthalic Acid >98.0%(GC)(T) | 13731-82-3 | 25g | $275 | 2025-07-31 | Buy |
| TRC | D426195 | 2,5-Dibromoterephthalic Acid | 13731-82-3 | 1g | $55 | 2021-12-16 | Buy |
| TRC | D426195 | 2,5-Dibromoterephthalic Acid | 13731-82-3 | 2.5g | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD70813 | 2,5-Dibromoterephthalic acid | 13731-82-3 | 25g | $55 | 2021-12-16 | Buy |
2,5-Dibromoterephthalic acid Chemical Properties,Uses,Production
Application
2,5-Dibromoterephthalic acid is an organic synthesis intermediate and a pharmaceutical intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis.
Chemical Properties
white crystalline powder
Synthesis
1074-24-4
13731-82-3
This embodiment describes a process for the synthesis of 2,5-dibromoterephthalic acid using 2,5-dibromo-1,4-dimethylbenzene as a starting material. NaBr (5 mmol) in 500 g of 97% acetic acid solution. The mixture was stirred at a constant rate using a gas dispersion stirrer to optimize the gas mixing, and then the mixture was heated to 150 °C and maintained for 2 h (this stage is labeled as "TI" in Table 1), after which it was warmed up to 180 °C to continue the reaction for 4 h (this stage is labeled as "T -2"). During the heating process, air is continuously vented at 400 psig (2.76 MPa) back pressure. At the end of the reaction, the pressure was released and the reactor was cooled to 50°C. The product was drained and the reactor was rinsed with 50 g of acetic acid in two passes to collect the residual product. The white solid product was collected by diafiltration, washed with water, and dried under vacuum to yield 310 g (84% yield) of 2,5-dibromoterephthalic acid as a white solid with 99% purity as determined by 1H NMR. Examples 2-5 explored the effect of different reaction stages, time and temperature conditions on the net yield and purity of 2,5-dibromoterephthalic acid, all following the procedure of Example 1, with the specific conditions adjusted as shown in Table 1. In all cases, the resulting 2,5-dibromoterephthalic acid was a white solid of not less than 99 mol% purity.
References
[1] Patent: US2010/168444, 2010, A1. Location in patent: Page/Page column 4-8
[2] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 5, p. 1781 - 1783
[3] Patent: WO2008/82501, 2008, A1. Location in patent: Page/Page column 15-16
[4] Journal of the American Chemical Society, 2014, vol. 136, # 43, p. 15414 - 15421
[5] Chemical Communications, 2010, vol. 46, # 35, p. 6503 - 6505
2,5-Dibromoterephthalic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CHEMSOON CO.,LTD. | +8613761723174 | sales01@chemsoon.com | China | 1211 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9948 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11728 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 2,5-Dibromoterephthalic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 2,5-Dibromoterephthalic Acid
13731-82-3
|
US $30.00-2.00 / kg | 1kg | 99 | g-kg-tons,free sample is available | Henan Fengda Chemical Co., Ltd | |
![]() |
2021-08-12 | 2,5-Dibromoterephthalic acid
13731-82-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
![]() |
2019-07-06 | 2'-Amino-1,1':4',1''-terphenyl-4,4''-dicarboxylic acid
13731-82-3
|
US $1.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
-

- 2,5-Dibromoterephthalic Acid
13731-82-3
- US $30.00-2.00 / kg
- 99
- Henan Fengda Chemical Co., Ltd
-

- 2,5-Dibromoterephthalic acid
13731-82-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- 2'-Amino-1,1':4',1''-terphenyl-4,4''-dicarboxylic acid
13731-82-3
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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