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2,5-Dibromoterephthalic acid

CAS No.
13731-82-3
Chemical Name:
2,5-Dibromoterephthalic acid
Synonyms
JACS-13731-82-3;2,5-Dibromoterephtha;2,5-Dibromterephthalsure;2,5-DibromoterephthalicAci;2,5-DIBROMOTEREPHTALIC ACID;2,5-DIBROMOTEREPHTHALIC ACID;2,5-dibromotetrephthalic acid;2,5-DibromoterephthalicAcid>2,5-dibromo-4-benzenedicarboxylicacid;2,5-Dibromo-1,4-PhenyldicarboxylicAcid
CBNumber:
CB0423720
Molecular Formula:
C8H4Br2O4
Molecular Weight:
323.92
MDL Number:
MFCD00204593
MOL File:
13731-82-3.mol
Last updated:2025-12-31 14:38:37
Product description Number Pack Size Price
2,5-Dibromoterephthalic Acid >98.0%(GC)(T) D3994 5g $70
2,5-Dibromoterephthalic Acid >98.0%(GC)(T) D3994 25g $275
2,5-Dibromoterephthalic Acid D426195 1g $55
2,5-Dibromoterephthalic Acid D426195 2.5g $65
2,5-Dibromoterephthalic acid FD70813 25g $55
More product size

2,5-Dibromoterephthalic acid Properties

Melting point 320-325°C
Boiling point 445.0±45.0 °C(Predicted)
Density 2.205±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
pka 1.75±0.10(Predicted)
form powder to crystal
color White to Almost white
InChIKey VUTICWRXMKBOSF-UHFFFAOYSA-N
CAS DataBase Reference 13731-82-3(CAS DataBase Reference)
FDA UNII 63JN659KM5
EPA Substance Registry System 1,4-Benzenedicarboxylic acid, 2,5-dibromo- (13731-82-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  C,Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36
TSCA  TSCA listed
HS Code  2917399590
NFPA 704
0
1 0

2,5-Dibromoterephthalic acid price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D3994 2,5-Dibromoterephthalic Acid >98.0%(GC)(T) 13731-82-3 5g $70 2025-07-31 Buy
TCI Chemical D3994 2,5-Dibromoterephthalic Acid >98.0%(GC)(T) 13731-82-3 25g $275 2025-07-31 Buy
TRC D426195 2,5-Dibromoterephthalic Acid 13731-82-3 1g $55 2021-12-16 Buy
TRC D426195 2,5-Dibromoterephthalic Acid 13731-82-3 2.5g $65 2021-12-16 Buy
Biosynth Carbosynth FD70813 2,5-Dibromoterephthalic acid 13731-82-3 25g $55 2021-12-16 Buy
Product number Packaging Price Buy
D3994 5g $70 Buy
D3994 25g $275 Buy
D426195 1g $55 Buy
D426195 2.5g $65 Buy
FD70813 25g $55 Buy

2,5-Dibromoterephthalic acid Chemical Properties,Uses,Production

Application

2,5-Dibromoterephthalic acid is an organic synthesis intermediate and a pharmaceutical intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis.

Chemical Properties

white crystalline powder

Synthesis

1,4-Dibromo-2,5-dimethylbenzene

1074-24-4

2,5-Dibromoterephthalic acid

13731-82-3

This embodiment describes a process for the synthesis of 2,5-dibromoterephthalic acid using 2,5-dibromo-1,4-dimethylbenzene as a starting material. NaBr (5 mmol) in 500 g of 97% acetic acid solution. The mixture was stirred at a constant rate using a gas dispersion stirrer to optimize the gas mixing, and then the mixture was heated to 150 °C and maintained for 2 h (this stage is labeled as "TI" in Table 1), after which it was warmed up to 180 °C to continue the reaction for 4 h (this stage is labeled as "T -2"). During the heating process, air is continuously vented at 400 psig (2.76 MPa) back pressure. At the end of the reaction, the pressure was released and the reactor was cooled to 50°C. The product was drained and the reactor was rinsed with 50 g of acetic acid in two passes to collect the residual product. The white solid product was collected by diafiltration, washed with water, and dried under vacuum to yield 310 g (84% yield) of 2,5-dibromoterephthalic acid as a white solid with 99% purity as determined by 1H NMR. Examples 2-5 explored the effect of different reaction stages, time and temperature conditions on the net yield and purity of 2,5-dibromoterephthalic acid, all following the procedure of Example 1, with the specific conditions adjusted as shown in Table 1. In all cases, the resulting 2,5-dibromoterephthalic acid was a white solid of not less than 99 mol% purity.

References

[1] Patent: US2010/168444, 2010, A1. Location in patent: Page/Page column 4-8
[2] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 5, p. 1781 - 1783
[3] Patent: WO2008/82501, 2008, A1. Location in patent: Page/Page column 15-16
[4] Journal of the American Chemical Society, 2014, vol. 136, # 43, p. 15414 - 15421
[5] Chemical Communications, 2010, vol. 46, # 35, p. 6503 - 6505

2,5-Dibromoterephthalic acid Preparation Products And Raw materials

Global( 244)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20128 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29735 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29833 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CHEMSOON CO.,LTD.
+8613761723174 sales01@chemsoon.com China 1211 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 9948 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 11728 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from 2,5-Dibromoterephthalic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dibromoterephthalic Acid pictures 2025-09-25 2,5-Dibromoterephthalic Acid
13731-82-3
US $30.00-2.00 / kg 1kg 99 g-kg-tons,free sample is available Henan Fengda Chemical Co., Ltd
2,5-Dibromoterephthalic acid pictures 2021-08-12 2,5-Dibromoterephthalic acid
13731-82-3
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2'-Amino-1,1':4',1''-terphenyl-4,4''-dicarboxylic acid pictures 2019-07-06 2'-Amino-1,1':4',1''-terphenyl-4,4''-dicarboxylic acid
13731-82-3
US $1.00 / KG 1KG 98% 100KG Career Henan Chemical Co

2,5-Dibromoterephthalic acid Spectrum

2,5-DIBROMOTEREPHTALIC ACID 2,5-DIBROMOTEREPHTHALIC ACID (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-hydroxy-5-methylphenoxy)-2-oxanecarboxylic acid 2,5-Dibromterephthalsure 2,5-dibromo-4-benzenedicarboxylicacid 2,5-Dibromoterephtha 1,4-DibroMo-2,5-benzenedicarboxylic acid 2,5-Dibromo-1,4-PhenyldicarboxylicAcid 2,5-dibromotetrephthalic acid 1,4-Benzenedicarboxylicacid, 2,5-dibroMo- JACS-13731-82-3 2,5-DibromoterephthalicAcid> 2,5-DibromoterephthalicAci 2,5-Dibromo-1,4-benzenedicarboxylic acid 13731-82-3 C8H4Br2O4 Br2C6H214CO2H2 Phthalic Acids, Esters and Derivatives Carboxylic Acids Phenyls & Phenyl-Het Organic acids Carboxylic Acids Phenyls & Phenyl-Het Derivatives of phthalic acid