Methyl L-threoninate hydrochloride
- CAS No.
- 39994-75-7
- Chemical Name:
- Methyl L-threoninate hydrochloride
- Synonyms
- L-THREONINE METHYL ESTER HYDROCHLORIDE;H-THR-OME HCL;H-THR-OME·HCL;H-L-THR-OME HCL;L-threonineamide;THREONINE-OME HCL;Lysine Impurity 7;H-Thr-OMe·HCl(oil);L-Threonine methyl e;H-Thr-OMe·HCl (Syrup)
- CBNumber:
- CB0427652
- Molecular Formula:
- C5H12ClNO3
- Molecular Weight:
- 169.61
- MDL Number:
- MFCD00037677
- MOL File:
- 39994-75-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| L-Threonine methyl ester hydrochloride | T5898 | 5g | $337 |
| L-Threonine methyl ester hydrochloride | T5898 | 25g | $816 |
| H-Thr-OMe·HCl | T2437 | 5G | $57 |
| H-Thr-OMe·HCl | T2437 | 25G | $172 |
| L-Threonine methyl ester hydrochloride 98+% | T41338 | 1g | $21 |
| More product size | |||
| Melting point | 64 °C |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| color | White |
| Water Solubility | Soluble in water. |
| Sensitive | Moisture Sensitive & Hygroscopic |
| BRN | 3562717 |
| InChI | 1S/C5H11NO3.ClH/c1-3(7)4(6)5(8)9-2;/h3-4,7H,6H2,1-2H3;1H/t3,4-;/m0./s1 |
| InChIKey | OZSJLLVVZFTDEY-LXNQBTANSA-N |
| SMILES | Cl.COC(=O)[C@@H](N)C(C)O |
| CAS DataBase Reference | 39994-75-7(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-21 | |||||||||
| HS Code | 29225000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Methyl L-threoninate hydrochloride price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T5898 | L-Threonine methyl ester hydrochloride | 39994-75-7 | 5g | $337 | 2026-04-30 | Buy |
| Sigma-Aldrich | T5898 | L-Threonine methyl ester hydrochloride | 39994-75-7 | 25g | $816 | 2023-06-20 | Buy |
| TCI Chemical | T2437 | H-Thr-OMe·HCl | 39994-75-7 | 5G | $57 | 2026-04-30 | Buy |
| TCI Chemical | T2437 | H-Thr-OMe·HCl | 39994-75-7 | 25G | $172 | 2026-04-30 | Buy |
| Synthonix | T41338 | L-Threonine methyl ester hydrochloride 98+% | 39994-75-7 | 1g | $21 | 2026-05-06 | Buy |
Methyl L-threoninate hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
L-Threonine methyl ester is a protected form of L-Threonine (T405500). L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin).
Synthesis
67-56-1
72-19-5
39994-75-7
1. L-Threonine was dissolved in a 2M solution of methanolic hydrochloric acid. 2. The reaction mixture was heated to reflux for 1 h. 3. The organic solvent was evaporated under reduced pressure using a rotary evaporator. 4. The same concentration of methanolic hydrochloric acid solution was added to the residue and heated to reflux again for 1 h. 5. Upon completion of the reaction, the organic solvent was evaporated under reduced pressure to give the white solid product, L-Threonine methyl ester hydrochloride. 6. The product was analyzed by ESI-MS and showed m/z of 134.2 [M+H]+.
References
[1] Journal of Medicinal Chemistry, 1995, vol. 38, # 15, p. 2851 - 2859
[2] Synthesis, 1999, # 10, p. 1739 - 1746
[3] Synthetic Communications, 2000, vol. 30, # 20, p. 3685 - 3691
[4] Bioorganic Chemistry, 2008, vol. 36, # 1, p. 4 - 15
[5] Synlett, 2009, # 8, p. 1227 - 1232
Methyl L-threoninate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1100 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29817 | 58 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from Methyl L-threoninate hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-14 | H-L-Thr-OMe.HCl
39994-75-7
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
![]() |
2025-06-27 | Methyl L-threoninate hydrochloride
39994-75-7
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2023-04-12 | High quality L-threonine methyl ester hydrochloridev
39994-75-7
|
US $15.00 / Kg/Bag | 1Kg/Bag | above 99% | Monthly supply of 1 ton | Wuhan Dujiang Industrial Co., Ltd. |
-

- H-L-Thr-OMe.HCl
39994-75-7
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-

- Methyl L-threoninate hydrochloride
39994-75-7
- US $30.00-10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- High quality L-threonine methyl ester hydrochloridev
39994-75-7
- US $15.00 / Kg/Bag
- above 99%
- Wuhan Dujiang Industrial Co., Ltd.





