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Methyl L-threoninate hydrochloride

CAS No.
39994-75-7
Chemical Name:
Methyl L-threoninate hydrochloride
Synonyms
L-THREONINE METHYL ESTER HYDROCHLORIDE;H-THR-OME HCL;H-THR-OME·HCL;H-L-THR-OME HCL;L-threonineamide;THREONINE-OME HCL;Lysine Impurity 7;H-Thr-OMe·HCl(oil);L-Threonine methyl e;H-Thr-OMe·HCl (Syrup)
CBNumber:
CB0427652
Molecular Formula:
C5H12ClNO3
Molecular Weight:
169.61
MDL Number:
MFCD00037677
MOL File:
39994-75-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:56:55
Product description Number Pack Size Price
L-Threonine methyl ester hydrochloride T5898 5g $337
L-Threonine methyl ester hydrochloride T5898 25g $816
H-Thr-OMe·HCl T2437 5G $57
H-Thr-OMe·HCl T2437 25G $172
L-Threonine methyl ester hydrochloride 98+% T41338 1g $21
More product size

Methyl L-threoninate hydrochloride Properties

Melting point 64 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
color White
Water Solubility Soluble in water.
Sensitive Moisture Sensitive & Hygroscopic
BRN 3562717
InChI 1S/C5H11NO3.ClH/c1-3(7)4(6)5(8)9-2;/h3-4,7H,6H2,1-2H3;1H/t3,4-;/m0./s1
InChIKey OZSJLLVVZFTDEY-LXNQBTANSA-N
SMILES Cl.COC(=O)[C@@H](N)C(C)O
CAS DataBase Reference 39994-75-7(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-37/39-26
WGK Germany  3
3-10-21
HS Code  29225000
Storage Class 11 - Combustible Solids
NFPA 704
1
1 0

Methyl L-threoninate hydrochloride price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T5898 L-Threonine methyl ester hydrochloride 39994-75-7 5g $337 2026-04-30 Buy
Sigma-Aldrich T5898 L-Threonine methyl ester hydrochloride 39994-75-7 25g $816 2023-06-20 Buy
TCI Chemical T2437 H-Thr-OMe·HCl 39994-75-7 5G $57 2026-04-30 Buy
TCI Chemical T2437 H-Thr-OMe·HCl 39994-75-7 25G $172 2026-04-30 Buy
Synthonix T41338 L-Threonine methyl ester hydrochloride 98+% 39994-75-7 1g $21 2026-05-06 Buy
Product number Packaging Price Buy
T5898 5g $337 Buy
T5898 25g $816 Buy
T2437 5G $57 Buy
T2437 25G $172 Buy
T41338 1g $21 Buy

Methyl L-threoninate hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

L-Threonine methyl ester is a protected form of L-Threonine (T405500). L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin).

Synthesis

Methanol

67-56-1

L-Threonine

72-19-5

Methyl L-threoninate hydrochloride

39994-75-7

1. L-Threonine was dissolved in a 2M solution of methanolic hydrochloric acid. 2. The reaction mixture was heated to reflux for 1 h. 3. The organic solvent was evaporated under reduced pressure using a rotary evaporator. 4. The same concentration of methanolic hydrochloric acid solution was added to the residue and heated to reflux again for 1 h. 5. Upon completion of the reaction, the organic solvent was evaporated under reduced pressure to give the white solid product, L-Threonine methyl ester hydrochloride. 6. The product was analyzed by ESI-MS and showed m/z of 134.2 [M+H]+.

References

[1] Journal of Medicinal Chemistry, 1995, vol. 38, # 15, p. 2851 - 2859
[2] Synthesis, 1999, # 10, p. 1739 - 1746
[3] Synthetic Communications, 2000, vol. 30, # 20, p. 3685 - 3691
[4] Bioorganic Chemistry, 2008, vol. 36, # 1, p. 4 - 15
[5] Synlett, 2009, # 8, p. 1227 - 1232

Methyl L-threoninate hydrochloride Preparation Products And Raw materials

Global( 357)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
Sichuan HongRi Pharma-Tech Co.,Ltd
+8618382028708 ni@enlaibio.com China 1100 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29640 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29817 58
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Methyl L-threoninate hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-L-Thr-OMe.HCl pictures 2026-05-14 H-L-Thr-OMe.HCl
39994-75-7
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
Methyl L-threoninate hydrochloride pictures 2025-06-27 Methyl L-threoninate hydrochloride
39994-75-7
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
 High quality L-threonine methyl ester hydrochloridev pictures 2023-04-12 High quality L-threonine methyl ester hydrochloridev
39994-75-7
US $15.00 / Kg/Bag 1Kg/Bag above 99% Monthly supply of 1 ton Wuhan Dujiang Industrial Co., Ltd.
  • H-L-Thr-OMe.HCl pictures
  • H-L-Thr-OMe.HCl
    39994-75-7
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd

Methyl L-threoninate hydrochloride Spectrum

L-Threonine methyl ester hydrochloride, 98+% L-threonineamide H-Thr-OMe·HCl(oil) L-Threonine methyl e (2S,3R)-Methyl 2-aMino-3-hydroxybutanoate hydrochloride H-Thr-OMe.Hcl (L-Threonine methyl ester hcl) H-Thr-OMe·HCl (yellowish oil) L-Threonine methyl ester hydrochloride≥ 98% (HPLC) L-Threonine methyleester hydrochloride THREONINE METHYL ESTER HYDROCHLORIDE THREONINE-OME HCL L-THREONINE METHYL ESTER HYDROCHLORIDE L-THREONINE METHYL ESTER HYDROCHLORIDE SALT methyl L-threoninate hydrochloride L-Threonine Methyl Ester HCl AZTREONAM INTERMEDIATES 2-amino-(2-diphenymethoxy-1,1-methyl-2-oxo-ethoxy imino-4-thiazole acetic acid Alpha-(2-aminothiazole-4yl)-alpha-(T-butoxycarbonyl)-isopropoxyimino acetic acid L-(Napha-carbobenzoxy)threonineamide H-Thr-OMe·HCl (Syrup) H-THR-OME HCL H-THR-OME HYDROCHLORIDE H-L-THR-OME HCL H-THR-OME·HCL methyl (2S,3R)-2-amino-3-hydroxybutanoate hydrochloride L-Threonine, methylester, hydrochloride (1:1) 2-amino-3-hydroxybutanoic acid methyl ester hydrochloride L-THEONINE METHYL ESTER HYDROCHLORIDE Lysine Impurity 7 Methyl L-threoninate hydrochloride USP/EP/BP High quality L-threonine methyl ester hydrochloridev Lysine Impurity 11 HCl L-Threonine Methyl Ester HCI methyl (2S,3R)-2-amino-3-hydroxybutanoate Lysine Impurity 2 HCl L-Threonine methyl ester hydrochloride L-Threonine methyl ester HCl, 98%min 39994-75-7 CH3CHOHCHNH2COOCH3HCl C5H11NO3xHCl C5H11NO3HCl Amino Acid Derivatives Peptide Synthesis Specialty Synthesis Threonine Threonine [Thr, T] Amino Acids and Derivatives Amino hydrochloride Peptide Synthesis Amino Acid Derivatives Amino Acids I - ZPeptide Synthesis Modified Amino Acids Threonine Aromatic Esters Amino Acids