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4-Fluoro-3-nitroaniline

CAS No.
364-76-1
Chemical Name:
4-Fluoro-3-nitroaniline
Synonyms
3-NITRO-4-FLUOROANILINE;4-Fluoro-3-nitrobenzenamine;4-F-3NA;uoro-3-nitroaniL;4-Fluoro-3-nitroanil;4-Fluor-3-nitroanilin;4-FLUORO-3-NITROANILINE;4-fluoro-3-nitro-anilin;4-Fluoro-3-phenylnitramine;4-Fluoro-3-nitroaniline98%
CBNumber:
CB0430717
Molecular Formula:
C6H5FN2O2
Molecular Weight:
156.11
MDL Number:
MFCD00007833
MOL File:
364-76-1.mol
MSDS File:
SDS
Last updated:2026-01-13 11:12:33
Product description Number Pack Size Price
4-Fluoro-3-nitroaniline 97% 155861 25g $26.11
4-Fluoro-3-nitroaniline 97% 155861 100g $142
4-Fluoro-3-nitroaniline >98.0%(GC) F0168 10g $23
4-Fluoro-3-nitroaniline >98.0%(GC) F0168 25g $34
4-Fluoro-3-nitroaniline F621950 5g $45
More product size

4-Fluoro-3-nitroaniline Properties

Melting point 94-96 °C (lit.)
Boiling point 331.3±22.0 °C(Predicted)
Density 0.43 g/cm3 (20℃)
Flash point 196 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 2.36±0.10(Predicted)
form Powder
color Ochre
Water Solubility Insoluble
BRN 2210199
InChI InChI=1S/C6H5FN2O2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H,8H2
InChIKey LLIOADBCFIXIEU-UHFFFAOYSA-N
SMILES C1(N)=CC=C(F)C([N+]([O-])=O)=C1
CAS DataBase Reference 364-76-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII R8DY9W4LRV
NIST Chemistry Reference Benzenamine, 4-fluoro-3-nitro-(364-76-1)
EPA Substance Registry System 4-Fluoro-3-nitroaniline (364-76-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS06
Signal word  Warning
Hazard statements  H315-H319-H301-H335-H302
Precautionary statements  P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-22
Safety Statements  36/37-37/39-26
RIDADR  UN 1325 4.1/PG 2
WGK Germany  2
RTECS  BY1700000
Hazard Note  Irritant
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  29214210
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 2
Limited Quantities 1.0 Kg (2.2 lbs)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
2 0

4-Fluoro-3-nitroaniline price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 155861 4-Fluoro-3-nitroaniline 97% 364-76-1 25g $26.11 2025-07-31 Buy
Sigma-Aldrich 155861 4-Fluoro-3-nitroaniline 97% 364-76-1 100g $142 2025-07-31 Buy
TCI Chemical F0168 4-Fluoro-3-nitroaniline >98.0%(GC) 364-76-1 10g $23 2021-12-16 Buy
TCI Chemical F0168 4-Fluoro-3-nitroaniline >98.0%(GC) 364-76-1 25g $34 2025-07-31 Buy
TRC F621950 4-Fluoro-3-nitroaniline 364-76-1 5g $45 2021-12-16 Buy
Product number Packaging Price Buy
155861 25g $26.11 Buy
155861 100g $142 Buy
F0168 10g $23 Buy
F0168 25g $34 Buy
F621950 5g $45 Buy

4-Fluoro-3-nitroaniline Chemical Properties,Uses,Production

Chemical Properties

whitetolightyellowcrystalpowde

Uses

4-Fluoro-3-nitroaniline is used in the preparation of commercial hair dyes. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals.

Uses

4-Fluoro-3-nitroaniline was used in the preparation of commercial hair dyes.

Definition

ChEBI: 4-fluoro-3-nitroaniline is a nitroaniline and an organofluorine compound.

Synthesis

2,4-Dinitrofluorobenzene

70-34-8

4-Fluoro-3-nitroaniline

364-76-1

2-Fluoro-5-nitroaniline

369-36-8

Example 43: General procedure for the synthesis of 4-fluoro-3-nitroaniline and 2-fluoro-5-nitroaniline from 2,4-dinitrofluorobenzene. A hydrogenation reaction was carried out according to the method described in Example 25 using 5% rhodium/alumina as a catalyst. This was done as follows: 18.61 g (0.10 mol) of 2,4-dinitrofluorobenzene was dissolved in a solvent mixture of 100 ml of glacial acetic acid and 100 ml of anhydrous ethanol in the presence of an alumina hydrogenation catalyst containing 0.50 g of rhodium. The hydrogen pressure was maintained at 370 psi during the reaction and the reaction time was 2 hours. Upon completion of the reaction, the product was separated by column chromatography to afford 2.79 g of 2-fluoro-5-nitroaniline in 17.6% yield. In addition, 0.85 g of 4-fluoro-3-nitroaniline was recovered as a second fraction.

References

[1] Tetrahedron Letters, 1990, vol. 31, # 43, p. 6141 - 6144
[2] Patent: US5105012, 1992, A
[3] Recueil des Travaux Chimiques des Pays-Bas, 1946, vol. 65, p. 329,330
[4] Russian Journal of General Chemistry, 2006, vol. 76, # 1, p. 76 - 81

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View Lastest Price from 4-Fluoro-3-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluoro-3-nitroaniline pictures 2026-03-06 4-Fluoro-3-nitroaniline
364-76-1
US $25.00 / KG 100KG 99.5% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
4-Fluoro-3-nitroaniline pictures 2026-03-06 4-Fluoro-3-nitroaniline
364-76-1
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-Fluoro-3-nitroaniline pictures 2026-03-05 4-Fluoro-3-nitroaniline
364-76-1
US $0.00-0.00 / kg 1kg 98% 20tons Sinoway Industrial co., ltd.
uoro-3-nitroaniL 4-FLUORO-3-NITRO-PHENYLAMINE 4-FLUORO-3-NITROANILINE 4-fluoro-3-nitro-benzamine 5-AMINO-2-FLUORONITROBENZENE 3-NITRO-4-FLUOROANILINE 4-Fluor-3-nitroanilin Benzenamine, 4-fluoro-3-nitro- 4-Fluoro-3-nitroaniline98% 4-Fluoro-3-phenylnitramine 4-FLUORO-3-NITROANILINE ( DRY ) 4-Fluoro-3-nitroaniline,99% 4-Fluoro-3-nitroanil 4-FLUORO-3-NITROANILINE FOR SYNTHESIS 4-AMino-2-nitrofluorobenzene[4-Fluoro-3-nitroaniline] 4-Amino-2-nitrofluorobenzene 4-F-3NA 4-fluoro-3-nitro-anilin 4-fluoro-3-nitro-benzenamin 4-Fluoro-3-nitrobenzenamine Aniline, 4-fluoro-3-nitro- 4-Fluoro-3-nitroaniline> 4-Fluoro-3-nitroaniline ISO 9001:2015 REACH 364-76-1 FNO2C6H3NH2 AMINE Analytical Chromatography Product Catalog C2 to C6 Analytical Standards Building Blocks Alphabetic Amines Organic Building Blocks Nitrogen Compounds FA - FL Fluorobenzene Series Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene API intermediates Amines C2 to C6 Nitrogen Compounds