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4-CHLOROISATIN

CAS No.
6344-05-4
Chemical Name:
4-CHLOROISATIN
Synonyms
4-CHLOROISATIN;BUTTPARK 50\07-90;4-CHLOROINDOLE-2,3-DIONE;4-CHLORO-2,3-INDOLINEDIONE;4-Chloro-(1H)-indole-2,3-dione;1H-Indole-2,3-dione, 4-chloro-;4-Chloro-2,3-dihydro-1H-indole-2,3-dione;4-chloro-1H-indole-2,3-dione(SALTDATA: FREE);4-Chloroindole-2,3-dione 4-Chloro-2,3-indolinedione
CBNumber:
CB0434508
Molecular Formula:
C8H4ClNO2
Molecular Weight:
181.58
MDL Number:
MFCD00129178
MOL File:
6344-05-4.mol
MSDS File:
SDS
Last updated:2025-08-29 17:52:28

4-CHLOROISATIN Properties

Melting point 258 °C
Density 1.519±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Dimethylformamide
form powder to crystal
pka 9.44±0.20(Predicted)
color Light yellow to Brown
CAS DataBase Reference 6344-05-4(CAS DataBase Reference)
FDA UNII U0NSS4B19Q

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2933998090
NFPA 704
0
2 0

4-CHLOROISATIN price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1870 4-Chloroisatin >97.0%(GC)(T) 6344-05-4 5g $26 2025-07-31 Buy
TCI Chemical C1870 4-Chloroisatin >97.0%(GC)(T) 6344-05-4 25g $80 2025-07-31 Buy
TRC C428602 4-Chloroisatin 6344-05-4 1g $65 2021-12-16 Buy
Biosynth Carbosynth FC38479 4-Chloroisatin 6344-05-4 25g $53.75 2021-12-16 Buy
Biosynth Carbosynth FC38479 4-Chloroisatin 6344-05-4 450g $405 2021-12-16 Buy
Product number Packaging Price Buy
C1870 5g $26 Buy
C1870 25g $80 Buy
C428602 1g $65 Buy
FC38479 25g $53.75 Buy
FC38479 450g $405 Buy

4-CHLOROISATIN Chemical Properties,Uses,Production

Chemical Properties

Orange powder

Uses

4-Chloroisatin is an isatic acid derivative that performs a plant growth-regulating activity. Isatin compounds also performs selective inhibitory functions against carboxylesterases.

Synthesis

Chloral hydrate

302-17-0

3-Chloroaniline

108-42-9

4-CHLOROISATIN

6344-05-4

Chloral hydrate (8.93 g, 0.054 mol), anhydrous sodium sulfate (130 g, 0.40 mol), m-chloroaniline (0.05 mol), hydroxylammonium chloride (10.98 g, 0.158 mol), and concentrated hydrochloric acid (43 mL) were added to 120 mL of water in sequence. The resulting suspension was heated to 90 °C, maintained for 5 minutes and cooled to room temperature. The reaction mixture was filtered and washed with water (2 x 20 mL) to obtain the crude product. The crude product was added in batches to a 250 mL three-necked flask pre-filled with concentrated sulfuric acid (32.6 mL) and preheated to 65 °C, after which the mixture was heated to 80 °C and maintained for 20 minutes. After completion of the reaction, the solution was cooled to room temperature and slowly poured into 500 g of ice water with vigorous stirring for 4 hours. The intermediate 4-chloroindoline-2,3-dione was isolated by filtration, washed with water and recrystallized from ethanol in a final yield of 25.7% to 73.2%.

References

[1] Chinese Chemical Letters, 2013, vol. 24, # 10, p. 929 - 933

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View Lastest Price from 4-CHLOROISATIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chloroisatin pictures 2025-09-06 4-Chloroisatin
6344-05-4
US $0.00 / kg 1kg 98% Customise Hefei Lbao Physical & Chemical Science Co.,Ltd
 4-Chloroisatin pictures 2025-08-29 4-Chloroisatin
6344-05-4
US $2.20-8.80 / kg 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-CHLOROISATIN pictures 2021-08-12 4-CHLOROISATIN
6344-05-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • 4-Chloroisatin pictures
  • 4-Chloroisatin
    6344-05-4
  • US $0.00 / kg
  • 98%
  • Hefei Lbao Physical & Chemical Science Co.,Ltd
  •  4-Chloroisatin pictures
  • 4-Chloroisatin
    6344-05-4
  • US $2.20-8.80 / kg
  • 99%min
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
  • 4-CHLOROISATIN pictures
  • 4-CHLOROISATIN
    6344-05-4
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

4-CHLOROISATIN Spectrum

4-CHLORO-2,3-INDOLINEDIONE 4-CHLOROISATIN 4-CHLOROINDOLE-2,3-DIONE 4-Chloro-(1H)-indole-2,3-dione BUTTPARK 50\07-90 4-Chloro-2,3-dihydro-1H-indole-2,3-dione 4-chloro-1H-indole-2,3-dione(SALTDATA: FREE) 4-Chloroindole-2,3-dione 4-Chloro-2,3-indolinedione 1H-Indole-2,3-dione, 4-chloro- 6344-05-4 6344-5-4 Simple Indoles Indoles Indane/Indanone and Derivatives Indoles Simple Indoles