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2-Isopropyl-4-(methylaminomethyl)thiazole

CAS No.
154212-60-9
Chemical Name:
2-Isopropyl-4-(methylaminomethyl)thiazole
Synonyms
2-ISOPROPYL-4-(METHYLAMINOMETHYL)THIAZOLE;N-Methyl-2-isopropyl-4-thiazoleMethylaMine;2-isopropyl-4-(N-methyl)aminomethylthiazole;(2-isopropylthiazol-4-yl)-N-methylmethanamine;1-(2-Isopropyl-4-thiazolyl)-N-methylmethanamine;1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine;N-methyl-1-(2-propan-2-yl-4-thiazolyl)methanamine;4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-;N-methyl-(2-isopropyl-1,3-thiazol-4-yl)methylamine;1-(2-isopropyl-1,3-thiazol-4-yl)-N-MethylMethanaMine
CBNumber:
CB0434553
Molecular Formula:
C8H14N2S
Molecular Weight:
170.28
MDL Number:
MFCD06797969
MOL File:
154212-60-9.mol
MSDS File:
SDS
Last updated:2025-12-11 10:28:54
Product description Number Pack Size Price
2-Isopropyl-4-(methylaminomethyl)thiazole I874655 100mg $60
2-Isopropyl-4-(methylaminomethyl)thiazole I874655 500mg $155
2-Isopropyl-4-(methylaminomethyl)thiazole I874655 50mg $45
2-Isopropyl-4-(methylaminomethyl)thiazole 95% 7H31-1-0E 1g $328
2-Isopropyl-4-(methylaminomethyl)thiazole 95+% 118951 5g $480
More product size

2-Isopropyl-4-(methylaminomethyl)thiazole Properties

Boiling point 230.9±15.0 °C(Predicted)
Density 1.039±0.06 g/cm3(Predicted)
storage temp. 2-8°C, protect from light
pka 8.06±0.10(Predicted)
Appearance Colorless to light yellow Liquid
InChI InChI=1S/C8H14N2S/c1-6(2)8-10-7(4-9-3)5-11-8/h5-6,9H,4H2,1-3H3
InChIKey HWSFABGWAXURNG-UHFFFAOYSA-N
SMILES S1C=C(CNC)N=C1C(C)C
CAS DataBase Reference 154212-60-9(CAS DataBase Reference)
EWG's Food Scores 1-2
FDA UNII G297848J78

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xn,N
Risk Statements  21/22-38-41-51/53
Safety Statements  26-36/37/39-61
HS Code  2934100090

2-Isopropyl-4-(methylaminomethyl)thiazole price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I874655 2-Isopropyl-4-(methylaminomethyl)thiazole 154212-60-9 100mg $60 2021-12-16 Buy
TRC I874655 2-Isopropyl-4-(methylaminomethyl)thiazole 154212-60-9 500mg $155 2021-12-16 Buy
TRC I874655 2-Isopropyl-4-(methylaminomethyl)thiazole 154212-60-9 50mg $45 2021-12-16 Buy
SynQuest Laboratories 7H31-1-0E 2-Isopropyl-4-(methylaminomethyl)thiazole 95% 154212-60-9 1g $328 2021-12-16 Buy
Matrix Scientific 118951 2-Isopropyl-4-(methylaminomethyl)thiazole 95+% 154212-60-9 5g $480 2021-12-16 Buy
Product number Packaging Price Buy
I874655 100mg $60 Buy
I874655 500mg $155 Buy
I874655 50mg $45 Buy
7H31-1-0E 1g $328 Buy
118951 5g $480 Buy

2-Isopropyl-4-(methylaminomethyl)thiazole Chemical Properties,Uses,Production

Uses

2-Isopropyl-4-(methylaminomethyl)thiazole is mainly used as a fine Chemical and intermediate.

Synthesis

5-CHLOROMETHYL-2-ISOPROPYL-THIAZOLE

40516-57-2

Methylamine

74-89-5

2-Isopropyl-4-(methylaminomethyl)thiazole

154212-60-9

To a 250 mL three-necked flask was added 4-(chloromethyl)-2-isopropylthiazole (9 g, 0.05 mol) and 40% aqueous methylamine solution (100 mL). The reaction mixture was heated to 50-60 °C and the reaction was stirred at this temperature overnight. After the reaction was completed, the mixture was cooled to room temperature. Dichloromethane (100 mL) and isopropanol (30 mL) were added to the reaction mixture, which was stirred thoroughly and left to stratify. The aqueous phase was separated and the aqueous phase was extracted with dichloromethane 3 times. All organic phases were combined and dried with anhydrous sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated under reduced pressure to remove the solvent. The crude product was purified by column chromatography (silica gel, appropriate eluent) to afford 2-isopropyl-4-(methylaminomethyl)thiazole (6.5 g, 74% yield) as a colorless liquid.

References

[1] Patent: CN104557763, 2017, B. Location in patent: Paragraph 0026; 0034; 0035; 0036; 0046; 0056; 0064-0066
[2] Patent: WO2006/90270, 2006, A1. Location in patent: Page/Page column 8-9

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View Lastest Price from 2-Isopropyl-4-(methylaminomethyl)thiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Isopropyl-4-(methylaminomethyl)thiazole pictures 2024-02-21 2-Isopropyl-4-(methylaminomethyl)thiazole
154212-60-9
US $800.00 / g 1g 98 500 Kg R&D Scientific Inc.
2-Isopropyl-4-(methylaminomethyl)thiazole pictures 2021-08-12 2-Isopropyl-4-(methylaminomethyl)thiazole
154212-60-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2-Isopropyl-4-(methylaminomethyl)thiazole pictures 2021-07-13 2-Isopropyl-4-(methylaminomethyl)thiazole
154212-60-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

2-Isopropyl-4-(methylaminomethyl)thiazole Spectrum

2-ISOPROPYL-4-(METHYLAMINOMETHYL)THIAZOLE 1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine 2-isopropyl-1,3-thiazol-4-methylmethanamine hydrochloride 2-Isopropyl-4-(Methylaminomethyl)Thiazole(IntermediateOfRitonavir) N-methyl-(2-isopropyl-1,3-thiazol-4-yl)methylamine 4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)- 1-(2-isopropyl-1,3-thiazol-4-yl)-N-methylmethanamine(SALTDATA: 2HCl 0.4H2O 0.01S8) 1-(2-isopropyl-1,3-thiazol-4-yl)-N-MethylMethanaMine [(2-Isopropyl-1,3-thiazol-4-yl)Methyl]MethylaMine 2HCl N-Methyl-2-isopropyl-4-thiazoleMethylaMine 2-isopropyl-4-(N-methyl)aminomethylthiazole N-methyl-1-(2-propan-2-yl-1,3-thiazol-4-yl)methanamine 2-Isopropil-4-(Methylaminomethyl) Thiazole(Ritonavir Intermediate) (2-isopropylthiazol-4-yl)-N-methylmethanamine 1-(2-Isopropyl-4-thiazolyl)-N-methylmethanamine N-methyl-1-(2-propan-2-yl-4-thiazolyl)methanamine N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amine hydrochloride 2-Isopropyl-4-(Methyl Amino Methyl) Thiazole (MTV-II) 154212-60-9 54212-60-9 C8H14N2S