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Boc-L-Tyr(tBu)-OH

Boc-L-Tyr(tBu)-OH structure

CAS No.: 47375-34-8

Chemical Name:: Boc-L-Tyr(tBu)-OH

Synonyms: BOC-TYR(TBU)-OH;Boc-Tyr(tBu);BOC-L-TYR(TBU)-OH;BOC-TYR(BUT)-OH;Boc-Tyr(tBul)-OH;TIMTEC-BB SBB006926;BOC-TYROSINE(TBU)-OH;Boc-Tyr(tBu)-OH 100g;Boc-Tyr(tBu)-OH, 99.0%;BOC-O-T-BUTYL-L-TYROSINE

CBNumber:: CB0434634

Molecular Formula:: C18H27NO5

Molecular Weight:: 337.41

MDL Number:: MFCD00065598

MOL File:: 47375-34-8.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
Boc-Tyr(tBu)-OH Novabiochem?	8.53023	5G	$199
Boc-Tyr(tBu)-OH Novabiochem?	8.53023	25g	$785
N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine >98.0%(HPLC)(T)	B3485	1g	$29
N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine >98.0%(HPLC)(T)	B3485	5g	$86
Boc-Tyr(tBu)-OH ≥99.0% (sum of enantiomers, TLC)	15434	5g	$238
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Boc-L-Tyr(tBu)-OH Properties

Melting point	113-118 °C
alpha	-15 º (C=1% IN DMF)
Boiling point	484.0±40.0 °C(Predicted)
Density	1.116±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	powder to crystal
pka	3.00±0.10(Predicted)
color	White to Almost white
optical activity	[α]20/D 15.0±1.0°, c = 1% in DMF
Water Solubility	Soluble in DMF. Insoluble in water.
BRN	4327336
InChI	InChI=1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1
InChIKey	ZEQLLMOXFVKKCN-AWEZNQCLSA-N
SMILES	C(O)(=O)[C@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference	47375-34-8(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

WGK Germany

HS Code

29242990

NFPA 704

	1
0		0

Boc-L-Tyr(tBu)-OH price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.53023	Boc-Tyr(tBu)-OH Novabiochem?	47375-34-8	5G	$199	2025-07-31	Buy
Sigma-Aldrich	8.53023	Boc-Tyr(tBu)-OH Novabiochem?	47375-34-8	25g	$785	2025-07-31	Buy
TCI Chemical	B3485	N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine >98.0%(HPLC)(T)	47375-34-8	1g	$29	2025-07-31	Buy
TCI Chemical	B3485	N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine >98.0%(HPLC)(T)	47375-34-8	5g	$86	2025-07-31	Buy
Sigma-Aldrich	15434	Boc-Tyr(tBu)-OH ≥99.0% (sum of enantiomers, TLC)	47375-34-8	5g	$238	2025-07-31	Buy

Product number	Packaging	Price	Buy
8.53023	5G	$199	Buy
8.53023	25g	$785	Buy
B3485	1g	$29	Buy
B3485	5g	$86	Buy
15434	5g	$238	Buy

Boc-L-Tyr(tBu)-OH Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

N-Boc-O-tert-butyl-L-tyrosine (Boc-L-Tyr(tBu)-OH) is used as pharmaceutical intermediate.

Application

Boc-Tyr(tBu)-OH is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. This compound could be used as a starting material to synthesize TPE-Tyr. TPE-Tyr can undergo covalent crosslinking via the formation of dityrosine linkages by exploiting horseradish peroxidase (HRP)-catalyzed phenol polymerization in the presence of H2O2, thereby activating the AIE process and switching on fluorescence emission of TPE core motif[1].

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

O-tert-butyl-L-tyrosine (2.00 g, 8.42 mmol, 1.0 equiv.) and di-tert-butyl dicarbonate (2.20 g, 10.10 mmol, 1.2 equiv.) were dissolved in a mixture of THF (15 mL) and NaOH (1 N, 30 mL) and stirred at room temperature for 10 h. THF was removed under reduced pressure, and the pH of residual solution was adjusted to 3.0 with dilute hydrochloric acid and the crude product was extracted by ethyl acetate. The combined organic phases was washed with saturated brine (pH 3.0) and dried over anhydrous Na2SO4. The organic solvent was removed under reduced pressure and dried in a vacuum oven at room temperature overnight, affording (N-Boc-O-tert-butyl)-L-Tyr (Boc-O-tert-butyl-L-tyrosine) as a yellowish solid (2.64 g, 93%)[1].

References

[1] Wang X, et al. Highly Selective Fluorogenic Multianalyte Biosensors Constructed via Enzyme-Catalyzed Coupling and Aggregation-Induced Emission. Journal of the American Chemical Society, 2014; 136: 9890–9893.

Boc-L-Tyr(tBu)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-4-[4-(tert-Butoxy)benzyl]oxazolidine-2,5-dione

Boc-L-Tyr(tBu)-OH Suppliers

Global( 275)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8617390183901	cynthia@enlaibio.com	China	1100	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14360	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Win-Win chemical CO., Limited	58

View Lastest Price from Boc-L-Tyr(tBu)-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-13	Boc-L-Tyr(tBu)-OH 47375-34-8	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2021-08-12	Boc-O-tert-butyl-L-tyrosine 47375-34-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	Boc-O-tert-butyl-L-tyrosine 47375-34-8	US $1.00 / KG	1KG	95%	500KG	Career Henan Chemical Co

Boc-L-Tyr(tBu)-OH
47375-34-8
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Boc-O-tert-butyl-L-tyrosine
47375-34-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Boc-O-tert-butyl-L-tyrosine
47375-34-8
US $1.00 / KG
95%
Career Henan Chemical Co

Boc-L-Tyr(tBu)-OH Spectrum

Boc-L-Tyr(tBu)-OH(47375-34-8)¹HNMR

47375-34-8(Boc-L-Tyr(tBu)-OH)Related Search:

tert-Butanol tert-Butyl hydroperoxide tert-Butyl methyl ether BUTYL OLEATE 4-tert-Butylcatechol

L-Tyrosine Cyhalofop-butyl 4-tert-Butylphenol Boc-Aib-OH Boc-D-Tyr-OH

tert-Butyldimethylsilyl chloride Buprofezin Methyl 4-tert-butylbenzoate TYROSINASE Dibutyl phthalate

BOC-GLY-LEU-OH Boc-Tyr(Me)-OH O-METHYL-D-TYROSINE

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(2S)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(tert-butoxy)phenyl]propanoic acid Boc-Tyr(tBu)-OH, 99.0% BOC-L-TYR(TBU)-OH BOC-O-T-BUTYL-L-TYROSINE BOC-O-TERT-BUTYL-L-TYROSINE BOC-TYR(TBU)-OH BOC-TYROSINE(TBU)-OH BOC-TYR(BUT)-OH TIMTEC-BB SBB006926 N-ALPHA-T-BOC-O-T-BUTYL-L-TYROSINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE N-ALPHA-T-BUTOXYCARBONYL-O-T-BUTYL-L-TYROSINE N-tert-Butoxycarbonyl-O-tert-butyl-L-tyrosine Boc-Tyr(tBul)-OH N-ALPHA-T-BUTYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE (S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid Boc-L-tyrosine beta-tert-butyl ester N-Boc-O-tert-butyl-L-tyrosine Boc-Tyr(tBu)-OH (S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)aMino)propanoic acid N-Boc-O-tert-butyl-L-tyrosine, 98% Boc-Tyr(tBu)-OH 100g (S)-2-(Boc-amino)-3-(4-tert-butoxyphenyl)propionic acid Boc-O-tert-butyl-L-tyrosine≥ 99% (HPLC) (Tert-Butoxy)Carbonyl Tyr(tBu)-OH Boc-Tyr(tBu) N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine > L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)- Boc-O-tert-butyl-L-tyrosine USP/EP/BP (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid BOC-0-tert-butyl-L-tyrosine 47375-34-8 CH33COC6H4CH2CHCOOHNHCOOCCH33 C18H27NO5 CARBOXYLIC ACID Peptide Synthesis Specialty Synthesis Tyrosine Amino Acid Derivatives Boc-Amino Acids and Derivative Boc-Amino acid series Amino Acids