TIMP-2, HUMAN
- CAS No.
- 124861-55-8
- Chemical Name:
- TIMP-2, HUMAN
- Synonyms
- Hexapeptide-12;DDC8;TIMP-2;CSC-21K;HUMAN TIMP-2;TIMP-2, HUMAN, R-DNA;Human Oligopeptide-20;TIMP-2, HUMAN, RECOMBINANT;Proteinase inhibitor TIMP2;TIMP-2, HUMAN。Hexapeptide-12
- CBNumber:
- CB0438465
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00285923
- MOL File:
- Mol file
| storage temp. | −20°C |
|---|---|
| form | buffered aqueous glycerol solution |
| color | white |
| biological source | human |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| Cosmetic Ingredient Review (CIR) | TIMP-2, HUMAN (124861-55-8) |
| EWG's Food Scores | 1 |
| UNSPSC Code | 12352202 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Hazard Codes | B,Xn,Xi |
| Risk Statements | 22-36/37/38-52/53 |
| Safety Statements | 23-24/25-61-26 |
| WGK Germany | 1 |
| Storage Class | 11 - Combustible Solids |
TIMP-2, HUMAN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3174 | TIMP-2 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture | 10 μg | $362 | 2025-07-31 | Buy | |
| Usbiological | 529083 | TIMP2 Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy | |
| Usbiological | 529083 | TIMP2 Purifiedbyimmunoaffinitychromatography. | 200ul | $944 | 2026-06-03 | Buy | |
| Usbiological | 529082 | TIMP2 Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy | |
| Usbiological | 529082 | TIMP2 Purifiedbyimmunoaffinitychromatography. | 200ul | $944 | 2026-06-03 | Buy |
TIMP-2, HUMAN Chemical Properties, Uses, Production
Description
rh-Polypeptide-15 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Tissue Inhibitor of Metalloproteinases-2. It contains a maximum of 220 amino acids
Biological Activity
Tissue inhibitor of metalloproteinase-2 (TIMP-2), like other protease inhibitors, functions as a key modulator of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through a matrix metalloproteinase (MMP)-independent mechanism inhibiting endothelial cell proliferation in vitro. It demonstrates anti-angiogenic activities in vivo. TIMP-2 is a target gene of the microRNA-miR-22.', 'TIMP-2 has a greater binding efficiency to MMP-2 than the other MMPs. Although TIMP-2 is an inhibitor of MMP-2, it is also required at low concentrations for the activation of MMP-2.
Background
TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases, the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently, the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors, and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.
TIMP-2, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
TIMP-2, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 15301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 13675144456 | alan.chow@synzest.com | China | 9467 | 58 |
| Zhangzhou Sinobioway Peptide Co. Ltd. | 18750546777 19559282110;18750546777 | Rocky@PEP-SYN.COM | China | 6096 | 58 |
View Latest Price from TIMP-2, HUMAN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-22 | Hexapeptide-12
124861-55-8
|
1kg | 98 | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2024-10-18 | Hexapeptide-12/HumanOligopeptide-20
124861-55-8
|
$30.00 | 1Box | 99.99% | 10000000000 | zhuzhou dingcheng meihei comestic co.,ltd | |
 |
2021-07-02 | TIMP-2.HUMAN
124861-55-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Hexapeptide-12
124861-55-8
- $0.00
- 98
- Shaanxi Dideu New Materials Co. Ltd
-
- Hexapeptide-12/HumanOligopeptide-20
124861-55-8
- $30.00
- 99.99%
- zhuzhou dingcheng meihei comestic co.,ltd
-
- TIMP-2.HUMAN
124861-55-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
