ChemicalBook >> CAS DataBase List >>3-Fluoro-5-(trifluoromethyl)benzoic acid
3-Fluoro-5-(trifluoromethyl)benzoic acid
- CAS No.
- 161622-05-5
- Chemical Name:
- 3-Fluoro-5-(trifluoromethyl)benzoic acid
- Synonyms
- BUTTPARK 32\01-71;RARECHEM AL BO 0634;3-Fluoro-5-(trifluor;5-tetrafluoro-m-toluic acid;3-Fluoro-5-(trifluoroMethyl...;à,à,à,5-tetrafluoro-m-toluic acid;3-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID;5-Fluoro-3-(trifluoromethyl)benzoic acid;3-Fluoro-5-(trifluoromethyl)benzoicacid98%;3-Fluoro-5-(trifluoromethyl)benzoicAcid>
- CBNumber:
- CB0445977
- Molecular Formula:
- C8H4F4O2
- Molecular Weight:
- 208.11
- MDL Number:
- MFCD00061293
- MOL File:
- 161622-05-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 22:42:35
| Product description | Number | Pack Size | Price |
| 3-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 455326 | 1g | $48 |
| 3-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 455326 | 5g | $57.4 |
| 3-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | F0759 | 1g | $31 |
| 3-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | F0759 | 5g | $94 |
| 3-Fluoro-5-(trifluoromethyl)benzoic acid 98% | PC4373C | 5g | $21 |
| More product size | |||
| Melting point | 104 °C |
|---|---|
| Boiling point | 239.6±40.0 °C(Predicted) |
| Density | 1.489±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.43±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C8H4F4O2/c9-6-2-4(7(13)14)1-5(3-6)8(10,11)12/h1-3H,(H,13,14) |
| InChIKey | NSGKIIGVPBTOBF-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(C(F)(F)F)=CC(F)=C1 |
| CAS DataBase Reference | 161622-05-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Fluoro-5-(trifluoromethyl)benzoic acid price More Price(72)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 455326 | 3-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 161622-05-5 | 1g | $48 | 2026-04-30 | Buy |
| Sigma-Aldrich | 455326 | 3-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 161622-05-5 | 5g | $57.4 | 2023-01-07 | Buy |
| TCI Chemical | F0759 | 3-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | 161622-05-5 | 1g | $31 | 2026-04-30 | Buy |
| TCI Chemical | F0759 | 3-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | 161622-05-5 | 5g | $94 | 2026-04-30 | Buy |
| Apolloscientific | PC4373C | 3-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 161622-05-5 | 5g | $21 | 2026-06-04 | Buy |
3-Fluoro-5-(trifluoromethyl)benzoic acid Chemical Properties,Uses,Production
Uses
3-Fluoro-5-(trifluoromethyl)benzoic acid is an organic intermediate that can be used to prepare αvβ6 integrin inhibitors and phosphodiesterase inhibitors.
Chemical Properties
White powder
Synthesis
Preparation of 3-fluoro-5-(trifluoromethyl)benzoic acid : In 100 ml four necked round bottom flask equipped with mechanical stirrer, thermometer, reflux condenser and an addition funnel, sodium hydroxide (6.35 g) and water (10 ml) was added and stirred for 15 mins at 25-35°C. To this, 3-fluoro-5- (trifluoromethyl)benzonitrile (10 g) was added and heated to 85-90°C. The reaction mass was stirred at 85-90°C for 2 hrs. After completion of reaction, the reaction mass was allowed to cool to 25-35°C. Then, the reaction mass was acidified with aqueous hydrochloric acid and stirred for 30 mins at 25-35°C. The solid formed was filtered, washed with water, suck dried and then dried under vacuum at 50-55°C for 6 hrs to get the title compound. Yield: 8 g.
3-Fluoro-5-(trifluoromethyl)benzoic acid Preparation Products And Raw materials
Global( 221)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from 3-Fluoro-5-(trifluoromethyl)benzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-05 | 3-fluoro-5-(trifluoromethyl)benzoic acid
161622-05-5
|
$310.00 | 1KG | 98%+ | 300 Tons/ year | Speranza Chemical Co., Ltd. | |
 |
2026-03-20 | 3-Fluoro-5-(trifluoromethyl)benzoic acid
161622-05-5
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-08-12 | 3-Fluoro-5-(trifluoromethyl)benzoic acid
161622-05-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3-fluoro-5-(trifluoromethyl)benzoic acid
161622-05-5
- $310.00
- 98%+
- Speranza Chemical Co., Ltd.
-
- 3-Fluoro-5-(trifluoromethyl)benzoic acid
161622-05-5
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Fluoro-5-(trifluoromethyl)benzoic acid
161622-05-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
161622-05-5(3-Fluoro-5-(trifluoromethyl)benzoic acid)Related Search:
Trifluoromethanesulfonic acid
3-(Trifluoromethyl)benzoic acid
p-Toluic acid
4-(Chloromethyl)benzoic acid
3,5-Dimethylbenzoic acid
o-Toluic acid
4-(Trifluoromethyl)benzoic acid
EPA
Lithium trifluoromethanesulfonate
4-Bromomethylbenzoic acid
1of4
RARECHEM AL BO 0634
BUTTPARK 32\01-71
ALPHA,ALPHA,ALPHA,5-TETRAFLUORO-M-TOLUIC ACID
3-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
à,à,à,5-tetrafluoro-m-toluic acid
3-Fluoro-5-(trifluoromethyl)benzoic acid 98%
3-Fluoro-5-(trifluoromethyl)benzoicacid98%
3-Carboxy-5-fluorobenzotrifluoride, alpha,alpha,alpha,5-Tetrafluoro-m-toluic acid
5-tetrafluoro-m-toluic acid
3-Fluoro-5-(trifluor
3-Fluoro-5-(trifluoroMethyl...
3-Fluoro-5-(trifluoromethyl)benzoicAcid>
Benzoic acid, 3-fluoro-5-(trifluoromethyl)-
5-Fluoro-3-(trifluoromethyl)benzoic acid
161622-05-5
ARYL ACID
Organic Building Blocks
Building Blocks
C8
Carbonyl Compounds
Carboxylic Acids
Building Blocks
Carbonyl Compounds
Carboxylic Acids
Chemical Synthesis
Fluorinated Building Blocks
Organic Building Blocks
Organic Fluorinated Building Blocks
Trifluoromethyl
Fluorine series
C8
Carbonyl Compounds
Carboxylic Acids
