4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER
- CAS No.
- 211738-66-8
- Chemical Name:
- 4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER
- Synonyms
- methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate;AKOS B001423;ART-CHEM-BB B001423;RARECHEM AL BF 1005;methyl 4-bromo-1-methylpyrazole-3-carboxylate;methyl 4-bromo-1-methyl-pyrazole-3-carboxylate;Methyl 4-bromo-1-methyl-1H-pyrazol-3-carboxylate;4-bromo-1-methyl-1H-pyrazole-3-methyl carboxylate;4-bromo-1-methyl-3-pyrazolecarboxylic acid methyl ester;4-bromo-1-methyl-pyrazole-3-carboxylic acid methyl ester
- CBNumber:
- CB0453077
- Molecular Formula:
- C6H7BrN2O2
- Molecular Weight:
- 219.04
- MDL Number:
- MFCD02253785
- MOL File:
- 211738-66-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | OR918037 | 100mg | $21 |
| Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | OR918037 | 250mg | $24 |
| Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | OR918037 | 1g | $29 |
| Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | OR918037 | 5g | $100 |
| Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | OR918037 | 25g | $430 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P501-P270-P264-P301+P310+P330-P405 |
| HazardClass | IRRITANT |
| HS Code | 2933199090 |
4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR918037 | Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | 211738-66-8 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR918037 | Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | 211738-66-8 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR918037 | Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | 211738-66-8 | 1g | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR918037 | Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | 211738-66-8 | 5g | $100 | 2026-06-04 | Buy |
| Apolloscientific | OR918037 | Methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate 98% | 211738-66-8 | 25g | $430 | 2026-06-04 | Buy |
4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER Chemical Properties,Uses,Production
Synthesis
81190-89-8
74-88-4
514816-42-3
211738-66-8
To a mixture of methyl 4-bromo-1H-pyrazole-3-carboxylate (15.0 g, 73.2 mmol) and Cs2CO3 (59.6 g, 182.9 mmol) in DMF (150 mL) was added slowly and dropwise at 0 °C under nitrogen protection iodomethane (14.7 mL, 236.0 mmol). The reaction mixture was stirred at 25 °C for 16 hours. After completion of the reaction, the mixture was filtered and the filter cake was washed with ethyl acetate (200 mL x 2). The combined filtrates were washed with water (70 mL x 4) and the aqueous phase was then back-extracted with ethyl acetate (150 mL). All organic phases were combined, dried with Na2SO4, filtered and concentrated to dryness under reduced pressure. The crude product was purified by fast column chromatography (gradient elution: petroleum ether/ethyl acetate from 100/0 to 50/50) to afford methyl 4-bromo-1-methyl-1H-pyrazole-3-carboxylate (240a, 8.3 g, 51.8% yield) and methyl 4-bromo-1-methyl-1H-pyrazole-5-carboxylate (240b, 7.0 g, 43.7% yield), both as white solid . 1H NMR (400 MHz, CDCl3) data for compound 240a: δ 7.48 (s, 1H), 4.15 (s, 3H), 3.93 (s, 3H). m/z (M + H) + 219.0 in MS (ESI).
References
[1] Patent: WO2018/64119, 2018, A1. Location in patent: Paragraph 1197
4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
View Lastest Price from 4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-08-08 | 4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER
211738-66-8
|
$3.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 4-BROMO-1-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID M ETHYL ESTER
211738-66-8
- $3.00
- 99%
- Career Henan Chemical Co
