CNICIN
- CAS No.
- 24394-09-0
- Chemical Name:
- CNICIN
- Synonyms
- CNICIN;CYNISIN;cnicine;CENTAURIN;Cnicin-RM;Aids104627;Aids-104627;-lactone,8-(3,4-dihydroxy-2-methylenebutyrate);2,3,3a,4,5,8,9,11a-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl 3,4-dihydroxy-2-methylenebutyrate;3,4-Dihydroxy-2-methylenebutanoic acid 2,3,3A,4,5,8,9,11A-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[B]furan-4-yl ester
- CBNumber:
- CB0456861
- Molecular Formula:
- C20H26O7
- Molecular Weight:
- 378.42
- MDL Number:
- MFCD00075707
- MOL File:
- 24394-09-0.mol
- MSDS File:
- SDS
| Melting point | 142-143°C |
|---|---|
| alpha | D20 +158° (c = 2.3 in ethanol) |
| Boiling point | 622.3±55.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 2-8°C |
| solubility |
Acetonitrile: Soluble Methanol: Soluble |
| form | Solid |
| pka | 12.77±0.20(Predicted) |
| color | White to off-white |
| LogP | 2.320 (est) |
| NCI Dictionary of Cancer Terms | cnicin |
| FDA UNII | C998MWY30L |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P280-P304+P340+P312-P337+P313-P403+P233 |
| Safety Statements | 22-24/25 |
| Toxicity | mouse,LD50,oral,452mg/kg (452mg/kg),Planta Medica. Vol. 53, Pg. 247, 1987. |
CNICIN price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FC65567 | Cynisin | 24394-09-0 | 1mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC65567 | Cynisin | 24394-09-0 | 2mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC65567 | Cynisin | 24394-09-0 | 5mg | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC65567 | Cynisin | 24394-09-0 | 10mg | $380 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000113 | CNICIN 95.00% | 24394-09-0 | 5MG | $500.39 | 2021-12-16 | Buy |
CNICIN Chemical Properties,Uses,Production
Uses
(+)-Cnicin is a useful research chemical exhibiting antifungal activity of sesquiterpene lactones from Centaurea species.
References
[1] ANKE BACHELIER Christian D K Ralf Mayer. Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA[J]. Bioorganic & Medicinal Chemistry Letters, 2006, 16 21: Pages 5605-5609. DOI: 10.1016/j.bmcl.2006.08.021
[2] VASILIKI SAROGLOU. Sesquiterpene Lactones from Centaurea spinosa and Their Antibacterial and Cytotoxic Activities[J]. Journal of Natural Products , 2005, 68 9: 1404-1407. DOI: 10.1021/np058042u
[3] TUGCE DEMIROZ . Anti-inflammatory properties of Centaurea calolepis Boiss. and cnicin against Macrovipera lebetina obtusa (Dwigubsky, 1832) and Montivipera xanthina (Gray, 1849) venoms in rat[J]. Toxicon, 2018, 152: Pages 37-42. DOI: 10.1016/j.toxicon.2018.07.016
CNICIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39030 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 | info@chemlin.com.cn | China | 14825 | 64 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7786 | 56 |
| Biyu Biotechnology (Shanghai) Co., ltd | 021-26018599 | China | 270 | 56 | |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
