Mirtazapine
- CAS No.
- 85650-52-8
- Chemical Name:
- Mirtazapine
- Synonyms
- Mirtazapine Anhydrous;REMERON;Mirtazapin;MIRTAZEPINE;Mirtazapine CRS;ZISPIN;ORG-3770;MIRTAZAPINE;MIRTAZANINE;Mirtazapine-d7
- CBNumber:
- CB0463388
- Molecular Formula:
- C17H19N3
- Molecular Weight:
- 265.35
- MDL Number:
- MFCD00865427
- MOL File:
- 85650-52-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Mirtazapine for system suitability European Pharmacopoeia (EP) Reference Standard | Y0000721 | 10 mg | $241 |
| Mirtazapine European Pharmacopoeia (EP) Reference Standard | Y0000705 | 10 mg | $241 |
| Mirtazapine solution 1.0?mg/mLinmethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant? | M-128 | 1mL | $101 |
| Mirtazapine ≥98% (HPLC) | M0443 | 10mg | $208 |
| Mirtazapine British Pharmacopoeia (BP) Reference Standard | BP842 | 100MG | $301 |
| More product size | |||
| Melting point | 114-116°C |
|---|---|
| Boiling point | 432.4±45.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Flash point | 9°C |
| storage temp. | 2-8°C |
| solubility | DMSO: ~8 mg/mL, soluble |
| form | solid |
| pka | 8.10±0.20(Predicted) |
| color | white |
| BCS Class | 1 |
| Major Application | pharmaceutical (small molecule) |
| InChI | InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 |
| InChIKey | RONZAEMNMFQXRA-UHFFFAOYSA-N |
| SMILES | N12CCN(C)CC1C1=CC=CC=C1CC1=CC=CN=C21 |
| CAS DataBase Reference | 85650-52-8(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | mirtazapine |
| FDA UNII | A051Q2099Q |
| NCI Drug Dictionary | mirtazapine |
| ATC code | N06AX11 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H336 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P301+P312-P304+P340+P312 | |||||||||
| target organs | Central nervous system | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UQ4410250 | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral STOT SE 3 |
|||||||||
| NFPA 704 |
|
Mirtazapine price More Price(92)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000721 | Mirtazapine for system suitability European Pharmacopoeia (EP) Reference Standard | 85650-52-8 | 10 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0000705 | Mirtazapine European Pharmacopoeia (EP) Reference Standard | 85650-52-8 | 10 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | M-128 | Mirtazapine solution 1.0?mg/mLinmethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant? | 85650-52-8 | 1mL | $101 | 2026-04-30 | Buy |
| Sigma-Aldrich | M0443 | Mirtazapine ≥98% (HPLC) | 85650-52-8 | 10mg | $208 | 2026-04-30 | Buy |
| Sigma-Aldrich | BP842 | Mirtazapine British Pharmacopoeia (BP) Reference Standard | 85650-52-8 | 100MG | $301 | 2026-04-30 | Buy |
Mirtazapine Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Mirtazapine (Remeron, Avanza) is a potent tetracyclic antidepressant. Mirtazapine (Remeron, Avanza) used primarily in the treatment of depression. It is also sometimes used as a hypnotic, antiemetic, and appetite stimulant, and for the treatment of anxiet
Uses
Mirtazapine is an α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.
Definition
ChEBI: Mirtazapine is a benzazepine and a tetracyclic antidepressant. It has a role as an alpha-adrenergic antagonist, a serotonergic antagonist, a histamine antagonist, an anxiolytic drug, a H1-receptor antagonist and a oneirogen.
brand name
Remeron (Organon).
General Description
Mirtazapine is a tetracyclic antidepressant marketed under the trade names Remeron, Avanza, or Zispin for treatment of depression.This Certified Spiking Solution is suitable for LC/MS or GC/MS applications in forensic analysis, clinical toxicology, or urine drug testing.
Biological Activity
Antidepressant agent; potent 5-HT 2 , 5-HT 3 and histamine H 1 receptor antagonist and moderately potent α 2 -adrenoceptor antagonist (pK i values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of α 2 -adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pK i values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo .
Biochem/physiol Actions
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.
Clinical Use
Antidepressant
Veterinary Drugs and Treatments
Currently, the only FDA approved indication for mirtazapine is
depression in humans. Reported veterinary uses include treatment
of chemotherapy-induced nausea and vomiting (CINV); anorexia
associated with renal failure (azotemia), congestive heart failure,
gastro-intestinal disorders, liver disease, or neoplasia. Other uses
suggested include stress induced diseases; insomnia; post-pyometra
symptoms; and post-operative inappetance. Studies have shown
that mirtazapine also alleviated sleep apnea in rats and humans.
There are case reports published in human literature of mirtazapine
use as treatment for non-mechanical vomiting after gastric
bypass, CINV, obsessive-compulsive disorder, nocioception
and chronic pain, migraine headache prophylaxis, anti-psychotic
induced akathisia, idiopathic nausea and vomiting, serotonin syndrome
induced nausea, anorexia, irritable bowel syndrome, resistant
hyperemesis gravidarum, and for the treatment of negative
symptoms of schizophrenia. Studies in rats have also shown that
mirtazapine significantly improves memory.
Drug interactions
Potentially hazardous interactions with other drugs
Alcohol: increased sedative effect.
Antidepressants: possibly increased risk of
serotonergic effects with fluoxetine, fluvoxamine or
venlafaxine; CNS excitation and hypertension with
MAOI and moclobemide - avoid.
Antimalarials: avoid with artemether and
lumefantrine and piperaquine with artenimol.
Methylthioninium: risk of CNS toxicity - avoid if
possible.
Metabolism
Extensively metabolised in the liver via CYP2D6, CYP1A2, and CYP3A4. The major biotransformation pathways are demethylation and oxidation followed by glucuronide conjugation. The N-desmethyl metabolite is pharmacologically active. Elimination is via urine and faeces (15%).
storage
Store at RT
Mirtazapine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 | admin@flanderff.com | China | 244 | 58 |
| Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 310 | 58 |
| Sinoway Industrial co., ltd. | +86-0592-5800732 +86-13806035118 | xie@china-sinoway.com | China | 1369 | 58 |
| Rongchuang International | +8613175533356 | kevin@rongchuangintl.com | China | 272 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
Related articles
- Mirtazapine: Antidepressant Mechanisms, Therapeutic Versatility, and Clinical Impact
- Mirtazapine is an antidepressant that belongs to a group of medicines called tetracyclic antidepressants which is used to trea....
- Apr 28，2025
View Lastest Price from Mirtazapine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-04 | Mirtazapine
85650-52-8
|
1kg | 99% | 99999 | Rongchuang International | ||
 |
2026-06-03 | Mirtazapine
85650-52-8
|
2Kg/Bag | USP | 20 tons | Sinoway Industrial co., ltd. | ||
 |
2026-06-02 | Mirtazapine
85650-52-8
|
$46.00-98.00 | 99.98% | 10g | TargetMol Chemicals Inc. |
-
- Mirtazapine
85650-52-8
- $0.00
- 99%
- Rongchuang International
-
- Mirtazapine
85650-52-8
- $0.00
- USP
- Sinoway Industrial co., ltd.
-
- Mirtazapine
85650-52-8
- $46.00-98.00
- 99.98%
- TargetMol Chemicals Inc.
