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(R)-(-)-1,3-Butanediol

(R)-(-)-1,3-Butanediol structure

CAS No.: 6290-03-5

Chemical Name:: (R)-(-)-1,3-Butanediol

Synonyms: (R)-1,3-BUTANEDIOL;L-Butane-1,3-diol;R13BG;1kg 10kg 100kg;(-)-1,3-Butanediol;(3R)-1,3-Butanediol;1,3-BUTANEDIOL, (R);1,3-Butanediol, (3R)-;(R)-(-)-1,3-BUTANEDIOL;(R)-(-)-BUTYLENE GLYCOL

CBNumber:: CB0465559

Molecular Formula:: C4H10O2

Molecular Weight:: 90.12

MDL Number:: MFCD00064277

MOL File:: 6290-03-5.mol

MSDS File:: SDS

Last updated:2025-10-09 14:55:14

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(R)-(-)-1,3-Butanediol Properties

Melting point	0.07°C (estimate)
alpha	-31 º (c=1 in EtOH)
Boiling point	107-110 °C/23 mmHg (lit.)
Density	1.005 g/mL at 25 °C (lit.)
vapor density	3.1 (vs air)
vapor pressure	0.06 mm Hg ( 20 °C)
refractive index	1.44
Flash point	250 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform, Ethanol
form	Oil
pka	14.83±0.20(Predicted)
color	Clear Colourless
optical activity	[α]21/D 31.0°, c = 1 in ethanol
Viscosity	97mm2/s
Water Solubility	Fully miscible in water.
Sensitive	Hygroscopic
BRN	1718944
InChIKey	PUPZLCDOIYMWBV-SCSAIBSYSA-N
LogP	-0.9 at 25℃
CAS DataBase Reference	6290-03-5(CAS DataBase Reference)
NIST Chemistry Reference	1,3-Butanediol, (R)-(6290-03-5)
EPA Substance Registry System	1,3-Butanediol, (3R)- (6290-03-5)
UNSPSC Code	12352001
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

EK0440000

3-10

Autoignition Temperature

741 °F

Hazard Note

Irritant

HS Code

29053920

NFPA 704

	1
1		0

(R)-(-)-1,3-Butanediol price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	237612	(R)-(?)-1,3-Butanediol 95%	6290-03-5	1g	$80.32	2025-07-31	Buy
TCI Chemical	B1159	(R)-(-)-1,3-Butanediol >98.0%(GC)	6290-03-5	1g	$53	2025-07-31	Buy
TCI Chemical	B1159	(R)-(-)-1,3-Butanediol >98.0%(GC)	6290-03-5	5g	$248	2025-07-31	Buy
TRC	B710010	(R)-(-)-1,3-Butanediol	6290-03-5	10g	$330	2021-12-16	Buy
American Custom Chemicals Corporation	CCH0000122	(R)-(-)-1,3-BUTANEDIOL 95.00%	6290-03-5	5G	$993	2021-12-16	Buy

Product number	Packaging	Price	Buy
237612	1g	$80.32	Buy
B1159	1g	$53	Buy
B1159	5g	$248	Buy
B710010	10g	$330	Buy
CCH0000122	5G	$993	Buy

(R)-(-)-1,3-Butanediol Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-1,3-Butanediol is used as a solvent for food flavoring agents and is a co-monomer used in certain polyurethane and polyester resins.

Application

(R)-(-)-1,3-Butanediol is a chiral reagent used in the synthesis of pharmaceuticals including the preparation of (-)-tarchonanthuslactone, a δ-lactone skeleton based compound with antiroliferative activity on cancer cell.

Definition

ChEBI: A butane-1,3-diol of R-configuration.

Flammability and Explosibility

Not classified

References

Novaes, L. et al.: ChemMedChem., 10, 1687 (2015);
Akinobu Matsuyama; Hiroaki Yamamoto; Naoki Kawada; Yoshinori Kobayashi. Industrial production of (R)-1,3-butanediol by new biocatalysts.Journal of Molecular Catalysis B: Enzymatic.2001,11(4-6), 513-521.
Naoki Ichikawa; Satoshi Sato; Ryoji Takahashi; Toshiaki Sodesawa; Harunori Fujita; Takashi Atoguchi; Akinobu Shiga. Theoretical investigation of 1,3-butanediol adsorption on an oxygen-defected CeO2(111) surface.Journal of Catalysis.2006,239(1), 13-22.

(R)-(-)-1,3-Butanediol synthesis

Synthesis of (R)-(-)-1,3-Butanediol from Methyl acetoacetate

(R)-(-)-1,3-Butanediol Preparation Products And Raw materials

Raw materials

r-butyrolactone Ethyl (R)-3-hydroxybutyrate 4-Hydroxy-2-butanone Methyl (R)-(-)-3-hydroxybutyrate (R)-3-Hydroxybutyric acid

Tosyl chloride Vinyl acetate Methyl acetoacetate Acetaldehyde

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Preparation Products

(S)-(+)-1,3-BUTANEDIOL

(R)-(-)-1,3-Butanediol Suppliers

Global( 231)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Weifang Wehibest Supply Chain Co.,Ltd	+8613583620690	hotspotbiotech@163.com	China	926	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3586	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12248	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9081	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1014	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Shandong Deshang Chemical Co., Ltd.	+86-0531-8875-2665 +8613153039501	info@deshangchem.com	China	661	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	9029	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60

Supplier	Advantage
Weifang Wehibest Supply Chain Co.,Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Shaanxi Didu New Materials Co. Ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
airuikechemical co., ltd.	58
Shandong Deshang Chemical Co., Ltd.	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60

View Lastest Price from (R)-(-)-1,3-Butanediol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-09	(R)-(-)-1,3-Butanediol 6290-03-5	US $42.00 / g		99.68%	10g	TargetMol Chemicals Inc.
2025-10-09	(R)-(-)-1,3-Butanediol 6290-03-5			0.99		RongNa Biotechnology Co.,Ltd
2025-08-13	(R)-(-)-1,3-Butanediol 6290-03-5	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd

(R)-(-)-1,3-Butanediol
6290-03-5
US $42.00 / g
99.68%
TargetMol Chemicals Inc.

(R)-(-)-1,3-Butanediol
6290-03-5
0.99
RongNa Biotechnology Co.,Ltd

(R)-(-)-1,3-Butanediol
6290-03-5
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

(R)-(-)-1,3-Butanediol Spectrum

(R)-(-)-1,3-Butanediol(6290-03-5)MS (R)-(-)-1,3-Butanediol(6290-03-5)¹HNMR (R)-(-)-1,3-Butanediol(6290-03-5)¹³CNMR (R)-(-)-1,3-Butanediol(6290-03-5)IR1 (R)-(-)-1,3-Butanediol(6290-03-5)Raman

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(R)-(-)-1,3-Butanediol (R)-(-)-1,3-Butanediol 98% L-Butane-1,3-diol 1,3-BUTANEDIOL, (R) (R)-(-)-BUTYLENE GLYCOL (R)-(-)-1,3-DIHYDROXYBUTANE (R)-(-)-1,3-BUTANEDIOL (R)-1,3-BUTANEDIOL (R)-(-)-1,3-BUTYLENE GLYCOL R13BG (3R)-1,3-Butanediol (R)-(-)-1,3-Butanediol,98% 1,3-Butanediol, (3R)- (3R)-(-)-Butane-1,3-diol (3R)-(-)-1,3-Dihydroxybutane (R)-(-)-1,3-Butylene Glycol (R)-(-)-1,3-Dihydroxybutane (-)-1,3-Butanediol (R)-(-)-1,3-Butanediol, 10 mM in DMSO 1kg 10kg 100kg 6290-03-5 6290-3-5 Asymmetric Synthesis Organic Building Blocks Polyols Simple Alcohols (Chiral) Chiral Building Blocks chiral Chiral Building Blocks Simple Alcohols (Chiral) Synthetic Organic Chemistry Chiral Building Blocks Organic Building Blocks Polyols Chiral Compounds Diols