MeCP2 Polyclonal Antibody
- CAS No.
- Chemical Name:
- MeCP2 Polyclonal Antibody
- Synonyms
- MeCP2 Polyclonal Antibody
- CBNumber:
- CB04814821
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
MeCP2 Polyclonal Antibody price More Price(1)
MeCP2 Polyclonal Antibody Chemical Properties, Uses, Production
Description
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. A demethylase enzyme has been identified which exhibits demethylase activity associated to a methyl-
References
[1] F PETRONZELLI. Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase.[J]. The Journal of Biological Chemistry, 2000, 275 42: 32422-32429. DOI: 10.1074/jbc.m004535200
[2] J F COY. A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3"-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression.[J]. Human molecular genetics, 1999, 8 7: 1253-1262. DOI: 10.1093/hmg/8.7.1253
[3] B HENDRICH A B. Identification and characterization of a family of mammalian methyl-CpG binding proteins.[J]. Molecular and Cellular Biology, 1998, 18 11: 6538-6547. DOI: 10.1128/mcb.18.11.6538
[4] SANJOY K. BHATTACHARYA. A mammalian protein with specific demethylase activity for mCpG DNA[J]. Nature, 1999, 397 6720: 579-583. DOI: 10.1038/17533
