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(S,R,S)-AHPC-PEG5-NH2 hydrochloride

(S,R,S)-AHPC-PEG5-NH2 hydrochloride Structure
(S,R,S)-AHPC-PEG5-NH2 hydrochloride structure
CAS No.
Chemical Name:
(S,R,S)-AHPC-PEG5-NH2 hydrochloride
Synonyms
(S,R,S)-AHPC-PEG5-NH2 hydrochloride
CBNumber:
CB04815671
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-01-27 09:38:02
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(S,R,S)-AHPC-PEG5-NH2 hydrochloride Properties

storage temp. 2-8°C
form crystals
UNSPSC Code 12352101
NACRES NA.22

(S,R,S)-AHPC-PEG5-NH2 hydrochloride price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 901850 (S,R,S)-AHPC-PEG5-NH2 hydrochloride 50 mg $1030 2025-07-31 Buy
Sigma-Aldrich 901850 (S,R,S)-AHPC-PEG5-NH2 hydrochloride 50mg $400 2024-03-01 Buy
Iris Biotech GmbH PTC1350 (S,R,S)-AHPC-PEG5-NH2 hydrochloride 50mg $648 2021-12-16 Buy
Product number Packaging Price Buy
901850 50 mg $1030 Buy
901850 50mg $400 Buy
PTC1350 50mg $648 Buy

(S,R,S)-AHPC-PEG5-NH2 hydrochloride Chemical Properties,Uses,Production

Uses

Protein degrader building block (SRS)-AHPC-PEG5-NH2 (HCl salt) enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel–Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with pendant amine for reactivity with a carboxyl group on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target E3 ligase and PROTAC many analogs are prepared to screen for optimal target degradation.When used with other protein degrader building blocks with a pendant amine parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length composition and E3 ligase ligand.

reaction suitability

reactivity: carboxyl reactive
reagent type: ligand-linker conjugate

(S,R,S)-AHPC-PEG5-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(S,R,S)-AHPC-PEG5-NH2 hydrochloride Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Supplier Advantage
Sigma-Aldrich 80
(S,R,S)-AHPC-PEG5-NH2 hydrochloride