LCB 03-0110 dihydrochloride (LCB03-0110)
- CAS No.
- 1962928-28-4
- Chemical Name:
- LCB 03-0110 dihydrochloride (LCB03-0110)
- Synonyms
- LCB 03-0110 dihydrochloride;LCB 03-0110 dihydrochloride (LCB03-0110);LCB 03-0110 dihydrochloride, 10 mM in DMSO;LCB 030110 dihydrochloride,LCB 03 0110 dihydrochloride
- CBNumber:
- CB04844976
- Molecular Formula:
- C24H24ClN3O2S
- Molecular Weight:
- 453.99
- MDL Number:
- MOL File:
- 1962928-28-4.mol
LCB 03-0110 dihydrochloride (LCB03-0110) Chemical Properties,Uses,Production
Description
LCB 03-0110 dihydrochloride is a potent c-Src kinase inhibitor (IC50 = 1.3 nM). It is also a potent inhibitor of BTK and Syk, discoidin domain receptor 2 (DDR2) family tyrosine kinases. The mechanism of action is it suppresses LPS-induced activation of macrophages and TGF-β1- induced activation of fibroblasts in vitro. LCB 03-0110 dihydrochloride also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model.
Uses
LCB 03-0110 dihydrochloride is a dihydrochloride of LCB 03-0110. LCB 03-0110 is a potent inhibitor of Src family tyrosine kinase[1].
storage
Desiccate at RT
References
[1] Sun X, et, al. LCB 03-0110, a novel pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor, suppresses scar formation by inhibiting fibroblast and macrophage activation. J Pharmacol Exp Ther. 2012 Mar;340(3):510-9. DOI:10.1124/jpet.111.187328
LCB 03-0110 dihydrochloride (LCB03-0110) Preparation Products And Raw materials
Raw materials
Preparation Products
LCB 03-0110 dihydrochloride (LCB03-0110) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24989 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| R&D Systems, Inc | 18003437475 | rdname@qq.com | China | 6960 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 6710 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
View Lastest Price from LCB 03-0110 dihydrochloride (LCB03-0110) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-30 | LCB 03-0110 dihydrochloride
1962928-28-4
|
US $71.00-163.00 / mg | 99.90% | 10g | TargetMol Chemicals Inc. |
-
- LCB 03-0110 dihydrochloride
1962928-28-4
- US $71.00-163.00 / mg
- 99.90%
- TargetMol Chemicals Inc.
