5-Bromo-2-chloronicotinic acid
- CAS No.
- 29241-65-4
- Chemical Name:
- 5-Bromo-2-chloronicotinic acid
- Synonyms
- 5-Bromo-2-Chloronicotinic;5-BROMO-2-CHLORONICOTINIC ACID;5-Bromo-2-chloronicotinic acid 97%;5-Bromo-2-chloronicotinic Acid >5-Bromo-2-chloronicotinic acid ,97%;5-bromo-2-chloropyridine-3-carboxylicaci;5-Bromo-2-chlorpyridine-3-carboxylic acid;5 - broMine - 2 - nicotinic acid chloride;5-BROMO-2-CHLORO-3-PYRIDINECARBOXYLIC ACID;5-BROMO-2-CHLOROPYRIDINE-3-CARBOXYLIC ACID
- CBNumber:
- CB0492683
- Molecular Formula:
- C6H3BrClNO2
- Molecular Weight:
- 236.45
- MDL Number:
- MFCD03844847
- MOL File:
- 29241-65-4.mol
| Melting point | 173-176°C |
|---|---|
| Boiling point | 345.1±42.0 °C(Predicted) |
| Density | 1.917±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | soluble in Methanol |
| pka | 1.61±0.25(Predicted) |
| form | Solid |
| color | White to Almost white |
| InChI | InChI=1S/C6H3BrClNO2/c7-3-1-4(6(10)11)5(8)9-2-3/h1-2H,(H,10,11) |
| InChIKey | UKNYSJCAGUXDOQ-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=C(Br)C=C1C(O)=O |
| CAS DataBase Reference | 29241-65-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
5-Bromo-2-chloronicotinic acid price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3883 | 5-Bromo-2-chloronicotinic Acid >98.0%(GC)(T) | 29241-65-4 | 5g | $86 | 2025-07-31 | Buy |
| TRC | B684108 | 5-Bromo-2-chloronicotinic Acid | 29241-65-4 | 500mg | $45 | 2021-12-16 | Buy |
| TRC | B684108 | 5-Bromo-2-chloronicotinic Acid | 29241-65-4 | 5g | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB75489 | 5-Bromo-2-chloronicotinic Acid | 29241-65-4 | 50g | $70 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H21-D-X0 | 5-Bromo-2-chloronicotinic acid 97% | 29241-65-4 | 25g | $39 | 2021-12-16 | Buy |
5-Bromo-2-chloronicotinic acid Chemical Properties,Uses,Production
Chemical Properties
Off-white powder
Synthesis
104612-36-4
29241-65-4
Step B. Synthesis of 5-bromo-2-chloronicotinic acid. A mixture of 5-bromo-2-hydroxynicotinic acid (32.9 g, 0.151 mol), dichlorosulfoxide (167 mL), and N,N-dimethylformamide (10.5 mL) was heated to reflux for 4 hours at 70°C. The reaction was carried out with the addition of water. Upon completion of the reaction, the mixture was concentrated, cooled to 0°C, and the reaction was quenched by the slow addition of water to give an off-white precipitate. The precipitate was stirred in water for 1 h and subsequently collected by filtration and dried under vacuum to give 5-bromo-2-chloronicotinic acid (35.5 g, 99% yield). The product can be used directly in the subsequent reaction without further purification or can be purified by recrystallization in hot water. Mass spectrum (electrospray ionization): calculated value C6H3BrClNO2, 234.90; measured value m/z, 236.2 [M + H]+. 1H NMR (acetone-d6): δ 8.66 (d, J = 2.5 Hz, 1H), 8.43 (d, J = 2.5 Hz, 1H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 9, p. 2566 - 2569
[2] Patent: US2006/287292, 2006, A1. Location in patent: Page/Page column 26
[3] European Journal of Organic Chemistry, 2010, # 28, p. 5397 - 5401
[4] Synthetic Communications, 1989, vol. 19, # 3and4, p. 553 - 560
[5] Patent: WO2010/136817, 2010, A1. Location in patent: Page/Page column 113
5-Bromo-2-chloronicotinic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12309 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 5-Bromo-2-chloronicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-28 | 5-Bromo-2-chloronicotinic acid
29241-65-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-24 | 5-Bromo-2-chloronicotinic acid
29241-65-4
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-10-26 | 5-Bromo-2-chloronicotinic acid
29241-65-4
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 5-Bromo-2-chloronicotinic acid
29241-65-4
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 5-Bromo-2-chloronicotinic acid
29241-65-4
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Bromo-2-chloronicotinic acid
29241-65-4
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
