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6-Chloro-1-indanone

CAS No.
14548-38-0
Chemical Name:
6-Chloro-1-indanone
Synonyms
6-choroindanone;6-Chloro-1-indanone;6-CHLORO-1-INDANONE 96;6-Chloro-1-indanone, 97+%;6-Chloro-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 6-chloro-2,3-dihydro-;JR-6918, 6-Chloro-2,3-dihydroinden-1-one, 97%
CBNumber:
CB0501491
Molecular Formula:
C9H7ClO
Molecular Weight:
166.6
MDL Number:
MFCD00956388
MOL File:
14548-38-0.mol
Last updated:2026-01-13 11:13:22
Product description Number Pack Size Price
6-Chloro-1-indanone 96% 656828 1g $160
6-Chloro-1-indanone 96% 656828 5g $703
6-Chloro-2,3-dihydro-1H-inden-1-one C433225 50mg $45
6-Chloro-2,3-dihydro-1H-inden-1-one C433225 100mg $60
6-Chloro-2,3-dihydro-1H-inden-1-one 97.0% 2617-5-29 250mg $70
More product size

6-Chloro-1-indanone Properties

Melting point 71-79 °C
Boiling point 110 °C(Press: 0.01 Torr)
Density 1.312±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form solid
Appearance White to off-white Solid
InChI 1S/C9H7ClO/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5H,2,4H2
InChIKey SMSGJDOJSQHQIW-UHFFFAOYSA-N
SMILES Clc1ccc2CCC(=O)c2c1
CAS DataBase Reference 14548-38-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H412
Precautionary statements  P273
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn
Risk Statements  22
WGK Germany  2
HazardClass  IRRITANT
HS Code  2914790090
Storage Class 13 - Non Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

6-Chloro-1-indanone price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 656828 6-Chloro-1-indanone 96% 14548-38-0 1g $160 2023-06-20 Buy
Sigma-Aldrich 656828 6-Chloro-1-indanone 96% 14548-38-0 5g $703 2023-06-20 Buy
TRC C433225 6-Chloro-2,3-dihydro-1H-inden-1-one 14548-38-0 50mg $45 2021-12-16 Buy
TRC C433225 6-Chloro-2,3-dihydro-1H-inden-1-one 14548-38-0 100mg $60 2021-12-16 Buy
SynQuest Laboratories 2617-5-29 6-Chloro-2,3-dihydro-1H-inden-1-one 97.0% 14548-38-0 250mg $70 2021-12-16 Buy
Product number Packaging Price Buy
656828 1g $160 Buy
656828 5g $703 Buy
C433225 50mg $45 Buy
C433225 100mg $60 Buy
2617-5-29 250mg $70 Buy

6-Chloro-1-indanone Chemical Properties,Uses,Production

Uses

6-Chloro-1-indanone is a chlorinated indanone compound. It is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.

Synthesis

3-(4-Chlorophenyl)propanoic acid

2019-34-3

6-Chloro-1-indanone

14548-38-0

General procedure for the synthesis of 6-chloro-2,3-dihydroinden-1-one from 3-(4-chlorophenyl)propionic acid: trifluoromethanesulfonic acid (3 equiv.) was slowly added to an anhydrous solution of 3-(4-chlorophenyl)propionic acid (0.5 mmol) in anhydrous dichloromethane (1.0 mL) in a 12 mL Q-tube pressure tube (supplied by QLabtech) at 0 °C. . The reaction mixture was then warmed to room temperature. A PTFE septum was placed on top of the reaction tube and sealed using the appropriate cap and pressure adapter. The sealed reaction tube was heated in an oil bath at 80°C. The progress of the reaction was monitored by thin layer chromatography (TLC) and gas chromatography-mass spectrometry (GC/MS) until the feedstock completely disappeared. After completion of the reaction, the mixture was poured into ice water and extracted three times with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Finally, the target compound 6-chloro-2,3-dihydroinden-1-one was purified from the crude product by fast column chromatography.

References

[1] Molecules, 2014, vol. 19, # 5, p. 5599 - 5610
[2] Patent: WO2017/150904, 2017, A1. Location in patent: Paragraph 402-404
[3] Synthetic Communications, 2007, vol. 37, # 13, p. 2171 - 2177
[4] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 8, p. 2554 - 2558
[5] Polish Journal of Chemistry, 1991, vol. 65, # 11, p. 2057 - 2060

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View Lastest Price from 6-Chloro-1-indanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-CHLORO-1-INDANONE pictures 2026-01-30 6-CHLORO-1-INDANONE
14548-38-0
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
6-CHLORO-1-INDANONE 96 pictures 2025-09-25 6-CHLORO-1-INDANONE 96
14548-38-0
US $36.00-1.50 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
6-Chloro-1-Indanone pictures 2025-09-25 6-Chloro-1-Indanone
14548-38-0
US $50.00-1.00 / kg 1kg 99 g-kg-tons,free sample is available Henan Fengda Chemical Co., Ltd

6-Chloro-1-indanone Spectrum

JR-6918, 6-Chloro-2,3-dihydroinden-1-one, 97% 6-CHLORO-1-INDANONE 96 6-Chloro-1-indanone 6-choroindanone 6-Chloro-2,3-dihydro-1H-inden-1-one 1H-Inden-1-one, 6-chloro-2,3-dihydro- 6-Chloro-1-indanone, 97+% 14548-38-0 96-13611-97-9 Building Blocks C9 Carbonyl Compounds Chemical Synthesis Ketones Organic Building Blocks API intermediates