OTUB1 antibody
- CAS No.
- Chemical Name:
- OTUB1 antibody
- Synonyms
- OTUB1 antibody;Rabbit Polyclonal OTUB1 Antibody
- CBNumber:
- CB05669196
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
OTUB1 antibody Chemical Properties, Uses, Production
Applications
OTUB1 antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity.
Immunogen
Anti-human OTUB1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human OTUB1 protein 1-271 amino acids purified from E. coli.
Background
Otubain 1 (OTUB1) belongs to the ovarian tumor (OUT) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system through its interaction with a ubiquitin protease and E3 ubiquitin ligase. OTUB1 is a highly specific ubiquitin iso-peptidase, it cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. OTUB1 is believed to work in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth. OTUB1 is a hydrolase that removes conjugated ubiquitin from proteins in vitro and may therefore have a significant regulatory role in the level of protein turnover by preventing degradation. Additionally, OTUB1 is a regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered impassive to antigen re-challenge and no longer respond to their cognate antigen. OTUB1 acts via its interaction with RNF128/GRAIL, which is an essential inductor of CD4 T-cell anergy.
OTUB1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
OTUB1 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
