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SHP836

SHP836 Structure
SHP836 structure
CAS No.
1957276-35-5
Chemical Name:
SHP836
Synonyms
SHP836;SHP836,SHP-836;4-Pyrimidinamine, 5-(2,3-dichlorophenyl)-2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-, rel-
CBNumber:
CB05821464
Molecular Formula:
C16H19Cl2N5
Molecular Weight:
352.26
MDL Number:
MFCD32701912
MOL File:
1957276-35-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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SHP836 Properties

Boiling point 526.8±60.0 °C(Predicted)
Density 1.278±0.06 g/cm3(Predicted)
pka 8.71±0.60(Predicted)
form Solid
color Light green to green

SHP836 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0083598 SHP836 99.39% 1957276-35-5 5mg $325 2026-06-04 Buy
ChemScene CS-0083598 SHP836 99.39% 1957276-35-5 10mg $520 2026-06-04 Buy
ChemScene CS-0083598 SHP836 99.39% 1957276-35-5 50mg $1571 2026-06-04 Buy
ChemScene CS-0083598 SHP836 99.39% 1957276-35-5 100mg $2362 2026-06-04 Buy
aablocks AA01V674 SHP836 >98% 1957276-35-5 5mg $369 2026-05-31 Buy
Product number Packaging Price Buy
CS-0083598 5mg $325 Buy
CS-0083598 10mg $520 Buy
CS-0083598 50mg $1571 Buy
CS-0083598 100mg $2362 Buy
AA01V674 5mg $369 Buy

SHP836 Chemical Properties, Uses, Production

Uses

SHP836 is a SHP2 allosteric inhibitor, with an IC50 of 12 μM for the full length SHP2[1].

References

[1] Liu WS, et al. Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluation. J Comput Aided Mol Des. 2019 Aug;33(8):759-774. DOI:10.1007/s10822-019-00213-z
[2] Garcia Fortanet J, et al. Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor. J Med Chem. 2016 Sep 8;59(17):7773-82. DOI:10.1021/acs.jmedchem.6b00680

SHP836 Preparation Products And Raw materials

Raw materials

Preparation Products

SHP836 Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
Guangzhou Ruidi Biotechnology Co., Ltd. 020-82099279 18988941402 sales@ubiochem.com China 9998 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
Guangzhou Ruidi Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from SHP836 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SHP836 pictures 2026-07-27 SHP836
1957276-35-5
 $332.00-1360.00 10g TargetMol Chemicals Inc.
  • SHP836 pictures
  • SHP836
    1957276-35-5
  • $332.00-1360.00
  • TargetMol Chemicals Inc.

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Okadaic acid

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SHP836 SHP836,SHP-836 4-Pyrimidinamine, 5-(2,3-dichlorophenyl)-2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-, rel- 1957276-35-5