1H-Benzimidazole-2-methanol
- CAS No.
- 4856-97-7
- Chemical Name:
- 1H-Benzimidazole-2-methanol
- Synonyms
- (1H-benzo[d]imidazol-2-yl)methanol;Compound Fr13702;IFLAB-BB F0266-0027;TIMTEC-BB SBB004085;2-HYDROXYBENXIMIDAZOLE;2-BENZIMIDAZOLEMETHANOL;BENZIMIDAZOLE-2-METHANOL;(2-Benzimidazolyl)methanol;1H-benzimidazol-2-methanol;1H-BENZIMIDAZOLE-2-METHANOL
- CBNumber:
- CB0666493
- Molecular Formula:
- C8H8N2O
- Molecular Weight:
- 148.16
- MDL Number:
- MFCD00014560
- MOL File:
- 4856-97-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Benzimidazolemethanol 97% | 158356 | 5g | $110 |
| 2-Benzimidazolemethanol 97% | 158356 | 1g | $39.8 |
| 2-(Hydroxymethyl)benzimidazole >98.0%(HPLC)(T) | H1229 | 5g | $134 |
| 1H-Benzimidazol-2-ylmethanol | 027686 | 500.00mg | $189 |
| (1h-Benzo[D]Imidazol-2-Yl)Methanol 95+% | B28661 | 1g | $25 |
| More product size | |||
| Melting point | 171-175 °C (lit.) |
|---|---|
| Boiling point | 268.75°C (rough estimate) |
| Density | 1.1828 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 11.57±0.10(Predicted) |
| form | Crystalline Powder |
| color | Off-white to light brown |
| InChI | InChI=1S/C8H8N2O/c11-5-8-9-6-3-1-2-4-7(6)10-8/h1-4,11H,5H2,(H,9,10) |
| InChIKey | IAJLTMBBAVVMQO-UHFFFAOYSA-N |
| SMILES | C1(CO)NC2=CC=CC=C2N=1 |
| CAS DataBase Reference | 4856-97-7(CAS DataBase Reference) |
| FDA UNII | 9SZ34H8DY7 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1H-Benzimidazole-2-methanol price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 158356 | 2-Benzimidazolemethanol 97% | 4856-97-7 | 5g | $110 | 2026-04-30 | Buy |
| Sigma-Aldrich | 158356 | 2-Benzimidazolemethanol 97% | 4856-97-7 | 1g | $39.8 | 2023-06-20 | Buy |
| TCI Chemical | H1229 | 2-(Hydroxymethyl)benzimidazole >98.0%(HPLC)(T) | 4856-97-7 | 5g | $134 | 2026-04-30 | Buy |
| Matrix Scientific | 027686 | 1H-Benzimidazol-2-ylmethanol | 4856-97-7 | 500.00mg | $189 | 2026-05-18 | Buy |
| Synthonix | B28661 | (1h-Benzo[D]Imidazol-2-Yl)Methanol 95+% | 4856-97-7 | 1g | $25 | 2026-05-06 | Buy |
1H-Benzimidazole-2-methanol Chemical Properties,Uses,Production
Chemical Properties
Off-white to light brown crystalline powder
Uses
2-Benzimidazolemethanol was used in the preparation of 2-(chloromethyl)-1-(methylsulfonyl)benzimidazole via methanesulfonylation. It was also used in the synthesis of 1H-benzimidazol-2-ylmethyl diethyl phosphate.
Synthesis
79-14-1
95-54-5
4856-97-7
The compound was prepared based on known methods with some modifications [19,20]. O-phenylenediamine (27 g, 0.25 mol) was dissolved in 500 mL of 4 M HCl, mixed with a solution of ethanoic acid (34.2 g, 0.45 mol) in 250 mL of 4 M HCl, stirred and heated under reflux conditions for 2 hours. Upon completion of the reaction, the reaction mixture was slowly cooled to room temperature and subsequently alkalized to pH neutral with aqueous sodium hydroxide. The precipitated solid was separated by filtration, dried and purified by recrystallization using hot water (Scheme 1). Product I was obtained: white to light brown powder, melting point 171-174 °C, yield 89.1%.
References
[1] Molecules, 2015, vol. 20, # 8, p. 15206 - 15223
[2] Bulletin of the Chemical Society of Ethiopia, 2014, vol. 28, # 3, p. 451 - 456
[3] Monatshefte fur Chemie, 2016, vol. 147, # 12, p. 2209 - 2220
[4] Patent: CN106905241, 2017, A. Location in patent: Paragraph 0127-0129
[5] Patent: CN107118249, 2017, A. Location in patent: Paragraph 0117; 0118; 0119
1H-Benzimidazole-2-methanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Wuhan Chemwonders Technology Inc. | 027-85778276 | info@chemwonders.com | CHINA | 176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
View Lastest Price from 1H-Benzimidazole-2-methanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-07-13 | 1H-Benzimidazole-2-methanol
4856-97-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 1H-Benzimidazole-2-methanol
4856-97-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-02 | 1H-Benzimidazole-2-methanol
4856-97-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 1H-Benzimidazole-2-methanol
4856-97-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1H-Benzimidazole-2-methanol
4856-97-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1H-Benzimidazole-2-methanol
4856-97-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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