2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE
- CAS No.
- 426463-09-4
- Chemical Name:
- 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE
- Synonyms
- 2-Chloro-5-iodopyridin-3-aMine;2-chloro-5-iodo-3-pyridinamine;3-AMINO-2-CHLORO-5-IODOPYRIDINE;2-Chloro-3-amino--5-iodopyridine;3-PyridinaMine, 2-chloro-5-iodo-;2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE;2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE ISO 9001：2015 REACH
- CBNumber:
- CB0681601
- Molecular Formula:
- C5H4ClIN2
- Molecular Weight:
- 254.46
- MDL Number:
- MFCD04038465
- MOL File:
- 426463-09-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Amino-2-chloro-5-iodopyridine 97% | 720372 | 1g | $108 |
| 2-Chloro-5-iodopyridin-3-amine 97% | AK113412 | 25g | $665 |
| 3-AMINO-2-CHLORO-5-IODOPYRIDINE 95.00% | HCH0066602 | 1G | $720.98 |
| 2-Chloro-5-iodopyridin-3-amine | 5887AB | 250mg | $81 |
| 2-Chloro-5-iodopyridin-3-amine 95+% | CD11125252 | 1g | $100 |
| More product size | |||
| Melting point | 128-133°C |
|---|---|
| Boiling point | 352.5±42.0 °C(Predicted) |
| Density | 2.139±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 0.27±0.10(Predicted) |
| form | solid |
| Appearance | White to off-white Solid |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H318 |
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338+P310 |
| Hazard Codes | Xn |
| Risk Statements | 22-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| HS Code | 2933399990 |
2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 720372 | 3-Amino-2-chloro-5-iodopyridine 97% | 426463-09-4 | 1g | $108 | 2023-01-07 | Buy |
| Ark Pharm | AK113412 | 2-Chloro-5-iodopyridin-3-amine 97% | 426463-09-4 | 25g | $665 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0066602 | 3-AMINO-2-CHLORO-5-IODOPYRIDINE 95.00% | 426463-09-4 | 1G | $720.98 | 2021-12-16 | Buy |
| AK Scientific | 5887AB | 2-Chloro-5-iodopyridin-3-amine | 426463-09-4 | 250mg | $81 | 2021-12-16 | Buy |
| Crysdot | CD11125252 | 2-Chloro-5-iodopyridin-3-amine 95+% | 426463-09-4 | 1g | $100 | 2021-12-16 | Buy |
2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE Chemical Properties,Uses,Production
Synthesis
426463-05-0
426463-09-4
General procedure for the synthesis of 3-amino-2-chloro-5-iodopyridine from 2-chloro-5-iodo-3-nitropyridine: 5-iodo-3-nitro-2-chloropyridine (230 mg, 0.809 mmol), ethanol (1 mL), water (6 drops), and concentrated hydrochloric acid (0.020 mL) were stirred at room temperature for 10 minutes. Subsequently, iron powder (500 mg, 8.95 mmol) was added in small portions and the reaction mixture was heated in an oil bath at 100 °C for 20 min. After completion of the reaction, the iron powder was removed by filtration and the filtrate was washed with ethanol. The ethanol layers were combined and concentrated under reduced pressure. The crude product was purified by fast chromatography using 9:1 hexane:ethyl acetate as eluent to afford 5-iodo-3-amino-2-chloropyridine (190 mg, 92% yield) as a colorless solid with a melting point of 129 °C. 1H NMR (CDCl3) δ (ppm): 4.15 (broad single peak, 2H), 7.34 (double peak, J = 2.0 Hz, 1H), and 7.96 (double peaks, J = 2.0 Hz, 1H); 13C NMR (CDCl3) δ (ppm): 91.41, 129.67, 136.31, 140.77, 143.90. Calculated values for elemental analysis (C5H4N2Cl): C, 23.60; H, 1.58; N, 11.01; Measured values: C, 23.66; H 1.52; N, 10.98.
References
[1] Journal of Organic Chemistry, 2011, vol. 76, # 23, p. 9841 - 9844
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 21, p. 4755 - 4761
[3] Patent: US6538010, 2003, B1
[4] Bioorganic & Medicinal Chemistry Letters, 2003, vol. 13, # 3, p. 525 - 528
2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20284 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39002 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53899 | 58 |
| ANHUI BYERSEN BIOTECH CO. LTD | +86-15385096007 +86-17755058861 | amy@byersenchemical.com | China | 10000 | 58 |
View Lastest Price from 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE
426463-09-4
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited |
-
- 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE
426463-09-4
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
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