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CHOLERA TOXIN

CHOLERA TOXIN Structure
CHOLERA TOXIN structure
CAS No.
9012-63-9
Chemical Name:
CHOLERA TOXIN
Synonyms
Cholergen;choleragen;CHOLERA TOXIN;Choleragenoid;choleraexotoxin;exo-enterotoxin;Toxins, cholera;CHOLERA ENTEROTOXIN;VIBRIO CHOLERAE TOXIN;choleraentero-exotoxin
CBNumber:
CB0683337
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00130776
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-05-27 22:50:03
Product description Number Pack Size Price
Cholera Toxin from Vibrio cholerae ≥90% (SDS-PAGE), lyophilized powder C8052 0.5mg $198
Cholera Toxin from Vibrio cholerae ~95% (SDS-PAGE) C8052 1mg $342
CholeraToxin,Vibriocholerae,TypeInaba569B,AzideFree-CAS9012-63-9-Calbiochem CholeratoxinInaba569B,CAS9012-63-9,hasasingleAsubunitsurroundedbyfi 227036 1mg $327
Cholera Toxin from Vibrio cholerae ≥95% (estimated by SDS-PAGE) 23217 1mg $188
Cholera Toxin from Vibrio cholerae ≥95% (estimated by SDS-PAGE) 23217 2mg $357
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CHOLERA TOXIN Properties

storage temp. 0-6°C
solubility H2O: soluble10mg/mL
form lyophilized powder
color White to off-white
Water Solubility H2O: 10mg/mL
FDA UNII SJ4QUS6E3E
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H300+H310-H332-H412
Precautionary statements  P262-P273-P280-P301+P310-P302+P352+P310-P304+P340+P312
Hazard Codes  T
Risk Statements  24/25-52/53
Safety Statements  36/37-45-61
RIDADR  3172
WGK Germany  2
RTECS  LF3100000
HazardClass  6.1
PackingGroup  I
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Dermal
Acute Tox. 2 Oral
Acute Tox. 4 Inhalation
Aquatic Chronic 3
Toxicity cholera toxin is secreted by the gram-negative bacterium Vibrio cholerae. It is a gastrointestinal toxin that increases adenylate cyclase activity of mucosa of the small intestine, thereby increasing cyclic AMP within these cells. Cyclic AMP stimulates active transport of ions by these epithelial cells, resulting in a large efflux of Na+ and water into the gut. The toxin enters cells by interacting with a GM1 ganglioside on the cell surface. After entry, the A1 subunit catalyzes the transfer of an ADP-ribose unit from NAD+ to an arginine side chain of the adenylate cyclase regulatory G protein, blocking its GTPase activity. Thus the adenylate cyclase deactivation mechanism is destroyed, and cyclic AMP is continually produced. The major sign of cholera poisoning is severe diarrhea; several liters of body water may be lost within a few hours, leading to shock and death if fluid is not replaced. Treatment involves physiological support (including i.v. fluids) and antibiotics.

CHOLERA TOXIN price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C8052 Cholera Toxin from Vibrio cholerae ≥90% (SDS-PAGE), lyophilized powder 9012-63-9 0.5mg $198 2026-04-30 Buy
Sigma-Aldrich C8052 Cholera Toxin from Vibrio cholerae ~95% (SDS-PAGE) 9012-63-9 1mg $342 2026-04-30 Buy
Sigma-Aldrich 227036 CholeraToxin,Vibriocholerae,TypeInaba569B,AzideFree-CAS9012-63-9-Calbiochem CholeratoxinInaba569B,CAS9012-63-9,hasasingleAsubunitsurroundedbyfi 9012-63-9 1mg $327 2026-04-30 Buy
Cayman Chemical 23217 Cholera Toxin from Vibrio cholerae ≥95% (estimated by SDS-PAGE) 9012-63-9 1mg $188 2021-12-16 Buy
Cayman Chemical 23217 Cholera Toxin from Vibrio cholerae ≥95% (estimated by SDS-PAGE) 9012-63-9 2mg $357 2021-12-16 Buy
Product number Packaging Price Buy
C8052 0.5mg $198 Buy
C8052 1mg $342 Buy
227036 1mg $327 Buy
23217 1mg $188 Buy
23217 2mg $357 Buy

CHOLERA TOXIN Chemical Properties,Uses,Production

Uses

Cholera Toxin from Vibrio cholerae has been used as a positive control in cAMP (cyclic AMP) assay for enterotoxins. It has been added as a supplement in cell culture media of primary tumors and epithelial cells.

Biochem/physiol Actions

Toxin consisting of an A subunit (27 kDa) surrounded by five B subunits (approximately 12 kDa each), which attach the toxin to ganglioside GM1 on the cell surface. The A subunit catalyzes ADP-ribosylation of the α-subunit of the stimulatory G protein (Gαs), reducing GTPase activity and activating the α-subunit. This activation of Gαs leads to an increase in the activity of adenylyl cyclase, resulting in increased levels of cAMP. Also ADP-ribosylates transducin in the eye rod outer segments, inactivating its GTPase activity. Cholera toxin has also been reported to ADP-ribosylate tubulin. Shown to be a potent mucosal vaccine adjuvant, inducing T helper cell type 2 responses by inhibiting the production of interleukin-12.

CHOLERA TOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

CHOLERA TOXIN Suppliers

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16512 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30225 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33324 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15838 69
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9815 79
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4769 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29757 58
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Career Henan Chemica Co 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Sinopharm Chemical Reagent Co,Ltd. 79
Guangzhou Isun Pharmaceutical Co., Ltd 55
Sigma-Aldrich 80
Beijing Jin Ming Biotechnology Co., Ltd. 58

View Lastest Price from CHOLERA TOXIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cholera toxin pictures 2026-04-17 Cholera toxin
9012-63-9
 $2.00-6.00 1KG 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
  • Cholera toxin pictures
  • Cholera toxin
    9012-63-9
  • $2.00-6.00
  • 99%
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

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Choleragenoid Cholera Toxin from Vibrio cholerae,Cholera enterotoxin, Cholergen Cholergen CHOLERA TOXIN CHOLERA ENTEROTOXIN CHOLERA TOXIN, VIBRIO CHOLERAE, TYPE INABA 569B VIBRIO CHOLERAE TOXIN choleraentero-exotoxin choleraexotoxin choleragen exo-enterotoxin exotoxin,vibriocholerae CHOLERA TOXIN FROM VIBRIO CHOLERAE Toxins, cholera Cholera Toxin, Vibrio cholerae, Type Inaba 569B, Azide Free Cholera Toxin from Vibrio cholerae Cholera toxin (Vibrio cholerae), (azide free) 9012-63-9 G Protein Function G Proteins and Cyclic Nucleotides Reagents BioChemical Cell Signaling and Neuroscience Cell Biology