Methacryloyl chloride
- CAS No.
- 920-46-7
- Chemical Name:
- Methacryloyl chloride
- Synonyms
- Methacrylic acid chloride;Methacryl chloride;Methacrylic chloride;Methacryloyl chlorid;2-METHYL-ACRYLOYL CHLORIDE;METHACRYLYL CHLORIDE;methylacryloylchloride;methacrylchloride;methacrylolchloride;methacrylicchloride
- CBNumber:
- CB0715425
- Molecular Formula:
- C4H5ClO
- Molecular Weight:
- 104.53
- MDL Number:
- MFCD00000716
- MOL File:
- 920-46-7.mol
- MSDS File:
- SDS
| Melting point | -60°C |
|---|---|
| Boiling point | 95-96 °C(lit.) |
| Density | 1.08 g/mL at 20 °C |
| refractive index |
n |
| Flash point | 57 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform |
| form | Liquid |
| color | Clear to slightly colored |
| Water Solubility | Miscible with alcohols, ethers and organic solvents. Slightly miscible with water. |
| Sensitive | Moisture Sensitive |
| BRN | 878175 |
| Stability | Light and Moisture Sensitive |
| InChIKey | VHRYZQNGTZXDNX-UHFFFAOYSA-N |
| CAS DataBase Reference | 920-46-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | L76O6653IO |
| NIST Chemistry Reference | Methacryloyl chloride(920-46-7) |
| EPA Substance Registry System | Methacryloyl chloride (920-46-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H302-H314-H317-H330-H412 | |||||||||
| Precautionary statements | P210-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | F,T+,Xi | |||||||||
| Risk Statements | 11-26/27/28-34-26-22-43-52/53 | |||||||||
| Safety Statements | 26-28-36/37/39-45-27-16-33-29 | |||||||||
| RIDADR | UN 3383 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OZ5791000 | |||||||||
| F | 21 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | I | |||||||||
| HS Code | 29161900 | |||||||||
| Hazardous Substances Data | 920-46-7(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| Excepted Quantities | Forbidden | |||||||||
| NFPA 704 |
|
Methacryloyl chloride price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 523216 | Methacryloyl chloride 97%, contains ~200ppm monomethyl ether hydroquinone as stabilizer | 920-46-7 | 100ml | $189 | 2026-04-30 | Buy |
| Sigma-Aldrich | 523216 | Methacryloyl chloride 97%, contains ~200ppm monomethyl ether hydroquinone as stabilizer | 920-46-7 | 1l | $1360 | 2026-04-30 | Buy |
| SynQuest Laboratories | 2316-5-02 | Methacryloyl chloride | 920-46-7 | 100mL | $295 | 2026-05-22 | Buy |
| Sigma-Aldrich | 64120 | Methacryloyl chloride purum, dist., ≥97.0% (GC), contains ~0.02% 2,6-di- | 920-46-7 | 50ml | $130 | 2023-06-20 | Buy |
| Sigma-Aldrich | 64120 | Methacryloyl chloride purum, dist., ≥97.0% (GC), contains ~0.02% 2,6-di- | 920-46-7 | 250ml | $467 | 2023-06-20 | Buy |
Methacryloyl chloride Chemical Properties, Uses, Production
Chemical Properties
clear slightly colored liquid
Uses
Methacryloyl chloride is used in the preparation of polymeric materials. It reacts with L-histidine and forms functional monomer. It is also used to prepare monomer 2-methacrylamido-caprolactam, amide monomers by amidation.
Application
Methacryloyl chloride is used in the manufacture of polymers:
Monomer 2-methacrylamido-caprolactam was prepared by reacting methacryloyl chloride with racemic a-amino-e-caprolactam.
Functional monomer was prepared by reacting methacryloyl chloride and L-histidine.
A series of amide monomers were synthesized by amidation of methacryloyl chloride with amines and grafted onto commercial poly(ether sulfone) (PES) membranes using irradiation from atmospheric pressure plasma (APP).
Reaction of methacryloyl chloride with the hydroxyl groups on the surfaces of HEMA/NVP microspheres was performed, leading to the introduction of polymerisable double bonds onto the surfaces of microspheres.
Star-shaped poly(d,l-lactide) oligomers with 2, 3 and 6 arms were synthesised, end-functionalised with methacryloyl chloride and photo-crosslinked in the presence of ethyl lactate as a non-reactive diluent.
General Description
Methacryloyl chloride is the clear to slightly colored acid chloride of methacrylic acid. It appears as a liquid of density 1.07g/cm3, boiling point 95-96°C, and flash point 55°F. Highly toxic. Supplied in technical grades of varying purity. Monomethyl ether hydroquinone is added as a stabilizer to prevent auto polymerization. Reaction with diisopropyl ether in presence of metal salts is rigorous.
Air & Water Reactions
Highly flammable. Reacts with water to produce gaseous hydrogen chloride (corrosive and toxic).
Reactivity Profile
Methacryloyl chloride is incompatible with strong oxidizing agents, alcohols, bases (including amines). Can polymerize violently; but the polymerization reaction can be inhibited by the addition of phenolthiazine. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Hazard
Flammable and corrosive liquid.
Synthesis
Using α-methacrylic acid as a raw material, it is reacted with liquid phosgene (trichloromethyl chloroformate) or solid phosgene (bis(trichloromethyl) carbonate) in the presence of a catalyst, followed by the addition of a polymerization inhibitor and distillation to obtain the target product. The specific method is as follows: 0.5–2 wt% of an organic basic catalyst and 0.1–1 wt% of a polymerization inhibitor are added to α-methacrylic acid. Solid or liquid phosgene is added dropwise over 1 hour at room temperature. After the addition is complete, the reaction is carried out at 20–75°C for 4–10 hours. Then, distillation is performed under atmospheric pressure, and the fraction collected at 95–98°C yields methacryloyl chloride.
Purification Methods
Purify the ester by fractional distillation. If it contains the acid (OH bands in the IR) then add redistilled SOCl2 (with cooling) and cuprous chloride (ca to 2%), reflux the mixture gently for 1hour and fractionate it through a 1metre column packed with glass helices. Redistillation then provides the acid chloride in high purity as a colourless liquid. It is necessary to keep the apparatus moisture free (use CaCl2 tubes), Stabilise it with 0.05% of 2,6-di-tert-butyl-4-methylphenol. [Lal & Green J Org Chem 20 1032 1955, Beilstein 2 IV 1537.]
Methacryloyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Beckman Chemical Technology Co., Ltd. | 029-68065899;81136681 15309292692 | fangxianwen@xa-bkm.com | China | 56 | 58 |
| Zibo Ward Chemical Technology Co., Ltd. | 0533-3585309 13287083616 | 13287083616@163.com | China | 6 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Chongqing Yuzhiquan Biological Technology Co., Ltd. | 18306022109 | 3236923470@qq.com | China | 283 | 58 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 | sales@heowns.com | China | 24650 | 60 |
| Shandong Junfeng New Materials Co., Ltd. | 17663721258 17663721258 | 17663721258@163.com | China | 364 | 58 |
| Xinlian Rui Biomedical Technology (Shandong) Co., Ltd | 0531-84567878 15153173989 | 3865799121@qq.com | China | 79 | 58 |
| Tianjin Zhongxin Chemtech Co., Ltd. | 022-66880623 | sales@tjzxchem.com | China | 612 | 60 |
| Wuhan EnTai Technology Development Co,.Ltd | 86-27-82330560 | 2536851935@qq.com | China | 346 | 69 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Latest Price from Methacryloyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-18 | Methacryloyl chloride
920-46-7
|
1KG | 99% | 500mt/year | Jinan Finer Chemical Co., Ltd | ||
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2026-06-30 | Methacryloyl chloride
920-46-7
|
1kg | 98% | 1000 | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-03-20 | Methacryloyl chloride
920-46-7
|
$9.90 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Methacryloyl chloride
920-46-7
- $0.00
- 99%
- Jinan Finer Chemical Co., Ltd
-
- Methacryloyl chloride
920-46-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Methacryloyl chloride
920-46-7
- $9.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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