NETROPSIN
- CAS No.
- 1438-30-8
- Chemical Name:
- NETROPSIN
- Synonyms
- f6;t1384;k-117;ia887;2814-a;Fusitin;NCI 3067;NSC 3067;ch-777-a;NETROPSIN
- CBNumber:
- CB0734505
- Molecular Formula:
- C18H26N10O3
- Molecular Weight:
- 430.46
- MDL Number:
- MFCD01941622
- MOL File:
- 1438-30-8.mol
Melting point | 171-173℃ |
---|---|
Boiling point | 544.74°C (rough estimate) |
Density | 1.3374 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | −20°C |
solubility | H2O: 1 mg/mL |
form | powder |
pka | 14.37±0.70(Predicted) |
color | faint yellow |
FDA UNII | 64B3O0RD7N |
EPA Substance Registry System | Netropsin (1438-30-8) |
NETROPSIN Chemical Properties,Uses,Production
Uses
Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity[1][2].
References
[1] Beerman TA et al. Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes. Biochim Biophys Acta. 1991 Aug 27;1090(1):52-60. DOI:10.1016/0167-4781(91)90036-l
[2] Finlay A C, et al. Netropsin, a new antibiotic produced by a Streptomyces. Journal of the American Chemical Society, 1951, 73(1): 341-343.
NETROPSIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12302 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5744 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32431 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 | wendy@huidabiotech.com | CHINA | 87 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7967 | 58 |
View Lastest Price from NETROPSIN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-08-19 | NETROPSIN
1438-30-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
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2025-06-24 | NETROPSIN
1438-30-8
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2020-02-02 | NETROPSIN
1438-30-8
|
US $1.00 / KG | 1KG | 99%HPLC | 200KG | Career Henan Chemical Co |
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