ChemicalBook >> CAS DataBase List >>NETROPSIN

NETROPSIN

CAS No.
1438-30-8
Chemical Name:
NETROPSIN
Synonyms
f6;t1384;k-117;ia887;2814-a;Fusitin;NCI 3067;NSC 3067;ch-777-a;NETROPSIN
CBNumber:
CB0734505
Molecular Formula:
C18H26N10O3
Molecular Weight:
430.46
MDL Number:
MFCD01941622
MOL File:
1438-30-8.mol
Last updated:2025-04-18 09:51:35

NETROPSIN Properties

Melting point 171-173℃
Boiling point 544.74°C (rough estimate)
Density 1.3374 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. −20°C
solubility H2O: 1 mg/mL
form powder
pka 14.37±0.70(Predicted)
color faint yellow
FDA UNII 64B3O0RD7N
EPA Substance Registry System Netropsin (1438-30-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  DW2973000
Toxicity LD50 oral in mouse: 300mg/kg

NETROPSIN Chemical Properties,Uses,Production

Uses

Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity[1][2].

References

[1] Beerman TA et al. Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes. Biochim Biophys Acta. 1991 Aug 27;1090(1):52-60. DOI:10.1016/0167-4781(91)90036-l
[2] Finlay A C, et al. Netropsin, a new antibiotic produced by a Streptomyces. Journal of the American Chemical Society, 1951, 73(1): 341-343.

NETROPSIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 89)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8617732866630 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd
+8613288715578 sales@hbmojin.com China 12302 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29800 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5744 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32431 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Zhejiang Huida Biotech Co., LTD
008613515763466 8615669048680 wendy@huidabiotech.com CHINA 87 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 7967 58

View Lastest Price from NETROPSIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NETROPSIN pictures 2025-08-19 NETROPSIN
1438-30-8
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
NETROPSIN pictures 2025-06-24 NETROPSIN
1438-30-8
US $1.00 / kg 1kg 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
NETROPSIN pictures 2020-02-02 NETROPSIN
1438-30-8
US $1.00 / KG 1KG 99%HPLC 200KG Career Henan Chemical Co
  • NETROPSIN pictures
  • NETROPSIN
    1438-30-8
  • US $0.00 / KG
  • 99%
  • Hebei Mujin Biotechnology Co.,Ltd
  • NETROPSIN pictures
  • NETROPSIN
    1438-30-8
  • US $1.00 / kg
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • NETROPSIN pictures
  • NETROPSIN
    1438-30-8
  • US $1.00 / KG
  • 99%HPLC
  • Career Henan Chemical Co
NETROPSIN ia887 k-117 n,4’-bi(pyrrole-2-carboxamide),n’-(2-carbamoylethyl)-4-((2-guanidinoacetimidoy t1384 NETROPSIN ULTRA PURE GRADE 98+% ultrapuregrade Congocidin, Sinanomycin NETROPSIN.2HCLRESEARCH GRADE Netropsin dihydrochloride,Congocidin, Sinanomycin 4-[[2-[(Aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-pyrrole-2-carboxamide NCI 3067 NSC 3067 1H-Pyrrole-2-carboxamide,4-[[2-[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl- 1’-dimethyl-l)amino)- 2814-a antibiotic1142 antibiotict-1384 ch-777-a congocidin f6 Netropsin dihydrochloride, dihydrate NETROPSIN USP/EP/BP Fusitin Netropsin dihydrochloride, DNA minor groove binding ligand 1438-30-8 C18H26N10O3 Antibiotics Antibiotics A to Z Antibiotics N-S BioChemical