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4-(Trifluoromethoxy)benzaldehyde

CAS No.
659-28-9
Chemical Name:
4-(Trifluoromethoxy)benzaldehyde
Synonyms
uoromethoxy)benzaL;Pretomanid Impurity 3;α,α,α-trifluoroanisaldehyde;4-trifluoromethoxylbenzaldehyde;-(Trifluoromethoxy)benzaldehyde;On trifluoroMethoxy benzaldehyde;P-(TRIFLUOROMETHOXY)BENZALDEHYDE;4-(TRIFLUOROMETHOXY)BENZALDEHYDE;4-Bromo-3-chloro-3-fluoroaniline;For trifluoromethoxy benzaldehyde
CBNumber:
CB0751924
Molecular Formula:
C8H5F3O2
Molecular Weight:
190.12
MDL Number:
MFCD00041530
MOL File:
659-28-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 22:53:15
Product description Number Pack Size Price
4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) T2256 5g $44
4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) T2256 25g $174
4-(Trifluoromethoxy)benzaldehyde Asreported 289828 1kg $2032
4-(Trifluoromethoxy)benzaldehyde Asreported 289828 2kg $2994
4-(Trifluoromethoxy)benzaldehyde Asreported 289828 5kg $5740
More product size

4-(Trifluoromethoxy)benzaldehyde Properties

Boiling point 93 °C27 mm Hg(lit.)
Density 1.331 g/mL at 25 °C(lit.)
refractive index n20/D 1.458(lit.)
Flash point 159 °F
storage temp. Inert atmosphere,2-8°C
form Liquid
Specific Gravity 1.331
color Clear colorless to pale yellow-green
Sensitive Air Sensitive
BRN 1949135
InChI InChI=1S/C8H5F3O2/c9-8(10,11)13-7-3-1-6(5-12)2-4-7/h1-5H
InChIKey XQNVDQZWOBPLQZ-UHFFFAOYSA-N
SMILES C(=O)C1=CC=C(OC(F)(F)F)C=C1
CAS DataBase Reference 659-28-9(CAS DataBase Reference)
NIST Chemistry Reference Benzaldehyde, 4-(trifluoromethoxy)-(659-28-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H227
Precautionary statements  P210e-P280a-P405-P501a-P261-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-36/38-22
Safety Statements  26-36/37/39-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29130000
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
2
2 0

4-(Trifluoromethoxy)benzaldehyde price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T2256 4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) 659-28-9 5g $44 2026-04-30 Buy
TCI Chemical T2256 4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) 659-28-9 25g $174 2026-04-30 Buy
Usbiological 289828 4-(Trifluoromethoxy)benzaldehyde Asreported 659-28-9 1kg $2032 2026-06-03 Buy
Usbiological 289828 4-(Trifluoromethoxy)benzaldehyde Asreported 659-28-9 2kg $2994 2026-06-03 Buy
Usbiological 289828 4-(Trifluoromethoxy)benzaldehyde Asreported 659-28-9 5kg $5740 2026-06-03 Buy
Product number Packaging Price Buy
T2256 5g $44 Buy
T2256 25g $174 Buy
289828 1kg $2032 Buy
289828 2kg $2994 Buy
289828 5kg $5740 Buy

4-(Trifluoromethoxy)benzaldehyde Chemical Properties,Uses,Production

Chemical Properties

clear colorless to pale yellow-green liquid

Uses

4-(Trifluoromethoxy)benzaldehyde is suitable for use in the synthesis of (E)-4-(trifluoromethoxy)benzaldehyde thiosemicarbazone. It may be used in the synthesis of:

  • new azo dyes containing of 5(4H)-oxazolone ring
  • 2-[4-(trifluoromethoxy)phenyl]-1H-benzimidazole
  • (E)-2-[4-(trifluoromethoxy)benzylidene]indan-1-one.

General Description

4-(Trifluoromethoxy)benzaldehyde (p-(trifluoromethoxy)benzaldehyde) is an aromatic aldehyde. It participates in the synthesis of 4,5-dihydro-4-(4-trifluoromethoxyphenyl)pyrrolo[1,2-a]quinoxaline.

Synthesis

In a flask with a reflux condenser and an inlet tube, 3.62 g of 4-trifluoromethoxybromobenzene, 0.21 g of bis(triphenylphosphine)palladium dichloride, and 1.53 g of sodium formate were added with 15 ml of DMF were mixed, stirred and heated to 110 C under the condition that CO was passed. After completion of the reaction (GC), the reaction mixture was cooled to 21 C and separated from the catalyst by silica gel filtration. . The crude product obtained contained 91% p-trifluoromethoxybenzaldehyde and 7% 4-trifluoromethoxybenzyl alcohol (percentages based on area ratio in GC).

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View Lastest Price from 4-(Trifluoromethoxy)benzaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(Trifluoromethoxy)benzaldehyde pictures 2026-02-02 4-(Trifluoromethoxy)benzaldehyde
659-28-9
10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
4-(Trifluoromethoxy)benzaldehyde pictures 2022-02-21 4-(Trifluoromethoxy)benzaldehyde
659-28-9
1KG 98.2% 100 tons Honest Joy Holdings Limited
4-(Trifluoromethoxy)benzaldehyde pictures 2021-08-12 4-(Trifluoromethoxy)benzaldehyde
659-28-9
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
α,α,α-trifluoroanisaldehyde 4-(Trifluoromethoxy)benzaldehyde 98% 4-(Trifluoromethoxy)benzaldehyde98% Benzaldehyde, 4-(trifluoromethoxy)- 4-(Trifluoromethoxy)benzaldehyde,99% On trifluoroMethoxy benzaldehyde 4-(TRIFLUOROMETHOXY)BENZALDEHYDE FOR SYN For trifluoromethoxy benzaldehyde 4-(TRIFLUOROMETHOXY)BENZALDEHYDE ALPHA,ALPHA,ALPHA-TRIFLUOROANISALDEHYDE P-(TRIFLUOROMETHOXY)BENZALDEHYDE uoromethoxy)benzaL Pretomanid Impurity 3 4-trifluoromethoxylbenzaldehyde 4-Bromo-3-chloro-3-fluoroaniline -(Trifluoromethoxy)benzaldehyde 659-28-9 5402-55-3 Organic Building Blocks Building Blocks Aldehydes C8 Carbonyl Compounds ALDEHYDE Pyridines Aromatic Aldehydes & Derivatives (substituted) Benzaldehyde Trifluoroanisole series Benzaldehyde series