4-(Trifluoromethoxy)benzaldehyde
- CAS No.
- 659-28-9
- Chemical Name:
- 4-(Trifluoromethoxy)benzaldehyde
- Synonyms
- uoromethoxy)benzaL;Pretomanid Impurity 3;α,α,α-trifluoroanisaldehyde;4-trifluoromethoxylbenzaldehyde;-(Trifluoromethoxy)benzaldehyde;On trifluoroMethoxy benzaldehyde;P-(TRIFLUOROMETHOXY)BENZALDEHYDE;4-(TRIFLUOROMETHOXY)BENZALDEHYDE;4-Bromo-3-chloro-3-fluoroaniline;For trifluoromethoxy benzaldehyde
- CBNumber:
- CB0751924
- Molecular Formula:
- C8H5F3O2
- Molecular Weight:
- 190.12
- MDL Number:
- MFCD00041530
- MOL File:
- 659-28-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) | T2256 | 5g | $44 |
| 4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) | T2256 | 25g | $174 |
| 4-(Trifluoromethoxy)benzaldehyde Asreported | 289828 | 1kg | $2032 |
| 4-(Trifluoromethoxy)benzaldehyde Asreported | 289828 | 2kg | $2994 |
| 4-(Trifluoromethoxy)benzaldehyde Asreported | 289828 | 5kg | $5740 |
| More product size | |||
| Boiling point | 93 °C27 mm Hg(lit.) |
|---|---|
| Density | 1.331 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 159 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | Liquid |
| Specific Gravity | 1.331 |
| color | Clear colorless to pale yellow-green |
| Sensitive | Air Sensitive |
| BRN | 1949135 |
| InChI | InChI=1S/C8H5F3O2/c9-8(10,11)13-7-3-1-6(5-12)2-4-7/h1-5H |
| InChIKey | XQNVDQZWOBPLQZ-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(OC(F)(F)F)C=C1 |
| CAS DataBase Reference | 659-28-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 4-(trifluoromethoxy)-(659-28-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H227 | |||||||||
| Precautionary statements | P210e-P280a-P405-P501a-P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-36/38-22 | |||||||||
| Safety Statements | 26-36/37/39-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29130000 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-(Trifluoromethoxy)benzaldehyde price More Price(72)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T2256 | 4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) | 659-28-9 | 5g | $44 | 2026-04-30 | Buy |
| TCI Chemical | T2256 | 4-(Trifluoromethoxy)benzaldehyde >97.0%(GC) | 659-28-9 | 25g | $174 | 2026-04-30 | Buy |
| Usbiological | 289828 | 4-(Trifluoromethoxy)benzaldehyde Asreported | 659-28-9 | 1kg | $2032 | 2026-06-03 | Buy |
| Usbiological | 289828 | 4-(Trifluoromethoxy)benzaldehyde Asreported | 659-28-9 | 2kg | $2994 | 2026-06-03 | Buy |
| Usbiological | 289828 | 4-(Trifluoromethoxy)benzaldehyde Asreported | 659-28-9 | 5kg | $5740 | 2026-06-03 | Buy |
4-(Trifluoromethoxy)benzaldehyde Chemical Properties,Uses,Production
Chemical Properties
clear colorless to pale yellow-green liquid
Uses
4-(Trifluoromethoxy)benzaldehyde is suitable for use in the synthesis of (E)-4-(trifluoromethoxy)benzaldehyde thiosemicarbazone. It may be used in the synthesis of:
- new azo dyes containing of 5(4H)-oxazolone ring
- 2-[4-(trifluoromethoxy)phenyl]-1H-benzimidazole
- (E)-2-[4-(trifluoromethoxy)benzylidene]indan-1-one.
General Description
4-(Trifluoromethoxy)benzaldehyde (p-(trifluoromethoxy)benzaldehyde) is an aromatic aldehyde. It participates in the synthesis of 4,5-dihydro-4-(4-trifluoromethoxyphenyl)pyrrolo[1,2-a]quinoxaline.
Synthesis
In a flask with a reflux condenser and an inlet tube, 3.62 g of 4-trifluoromethoxybromobenzene, 0.21 g of bis(triphenylphosphine)palladium dichloride, and 1.53 g of sodium formate were added with 15 ml of DMF were mixed, stirred and heated to 110 C under the condition that CO was passed. After completion of the reaction (GC), the reaction mixture was cooled to 21 C and separated from the catalyst by silica gel filtration. . The crude product obtained contained 91% p-trifluoromethoxybenzaldehyde and 7% 4-trifluoromethoxybenzyl alcohol (percentages based on area ratio in GC).
4-(Trifluoromethoxy)benzaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 4-(Trifluoromethoxy)benzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-02 | 4-(Trifluoromethoxy)benzaldehyde
659-28-9
|
10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
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2022-02-21 | 4-(Trifluoromethoxy)benzaldehyde
659-28-9
|
1KG | 98.2% | 100 tons | Honest Joy Holdings Limited | ||
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2021-08-12 | 4-(Trifluoromethoxy)benzaldehyde
659-28-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 4-(Trifluoromethoxy)benzaldehyde
659-28-9
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-

- 4-(Trifluoromethoxy)benzaldehyde
659-28-9
- $0.00
- 98.2%
- Honest Joy Holdings Limited
-

- 4-(Trifluoromethoxy)benzaldehyde
659-28-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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