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Triethylamine hydrochloride

Triethylamine hydrochloride structure

CAS No.: 554-68-7

Chemical Name:: Triethylamine hydrochloride

Synonyms: TRIETHYLAMMONIUM CHLORIDE;TRIETHYLAMINE HCL;Et3·HCl;[E3N]HCl;Trimethylamine Hci;Triethylamine hydroc;Triethylammoniumchlorid;Tolzaoline bydrochloride;TriethylaminHydrochlorid;triethylammomium chloride

CBNumber:: CB0767833

Molecular Formula:: C6H16ClN

Molecular Weight:: 137.65

MDL Number:: MFCD00012500

MOL File:: 554-68-7.mol

MSDS File:: SDS

Last updated:2026-05-27 22:53:51

Product description	Number	Pack Size	Price
Triethylamine hydrochloride ≥99.0% (AT)	90350	50g	$49.5
Triethylamine hydrochloride ≥99.0% (AT)	90350	1kg	$193
Triethylammonium chloride for synthesis	8.21135	5G	$44.7
Triethylammonium chloride for synthesis	8.21135	250g	$71.7
Triethylammonium chloride for synthesis	8.21135	1kg	$243
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Triethylamine hydrochloride Properties

Melting point	261 °C (dec.)(lit.)
Boiling point	223.18°C (rough estimate)
bulk density	220kg/m3
Density	1.07
refractive index	1.4530 (estimate)
storage temp.	Store below +30°C.
solubility	1440 g/L (20°C)
form	Crystalline Powder
color	White to off-white
PH	5 (10g/l, H2O, 20℃)
Water Solubility	1440 g/L (20 ºC)
Sensitive	Hygroscopic
Merck	14,9666
BRN	3906409
InChI	1S/C6H15N.ClH/c1-4-7(5-2)6-3;/h4-6H2,1-3H3;1H
InChIKey	ILWRPSCZWQJDMK-UHFFFAOYSA-N
SMILES	Cl.CCN(CC)CC
CAS DataBase Reference	554-68-7(CAS DataBase Reference)
FDA UNII	0NX3818GCW
EPA Substance Registry System	Ethanamine, N,N-diethyl-, hydrochloride (554-68-7)
UNSPSC Code	41116105
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-36-36/37/39-22

WGK Germany

RTECS

YE2111500

TSCA

TSCA listed

HS Code

29211910

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Hazardous Substances Data

554-68-7(Hazardous Substances Data)

Toxicity

LDLo scu-mus: 600 mg/kg JPETAB 37,309,29

REACH Registrations

Active

NFPA 704

	1
2		0

Triethylamine hydrochloride price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	90350	Triethylamine hydrochloride ≥99.0% (AT)	554-68-7	50g	$49.5	2026-04-30	Buy
Sigma-Aldrich	90350	Triethylamine hydrochloride ≥99.0% (AT)	554-68-7	1kg	$193	2026-04-30	Buy
Sigma-Aldrich	8.21135	Triethylammonium chloride for synthesis	554-68-7	5G	$44.7	2026-04-30	Buy
Sigma-Aldrich	8.21135	Triethylammonium chloride for synthesis	554-68-7	250g	$71.7	2026-04-30	Buy
Sigma-Aldrich	8.21135	Triethylammonium chloride for synthesis	554-68-7	1kg	$243	2026-04-30	Buy

Product number	Packaging	Price	Buy
90350	50g	$49.5	Buy
90350	1kg	$193	Buy
8.21135	5G	$44.7	Buy
8.21135	250g	$71.7	Buy
8.21135	1kg	$243	Buy

Triethylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White to off-white crystalline powder

Uses

Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.

Hazard

Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Targets the central nervous system, liver, kidneys, and heart. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.

Safety Profile

Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of NOx, HCl, and Clí.

Solubility in organics

Soluble in ethanol, chloroform, and alcohol. Insoluble in ether.

Purification Methods

Purify it like the bromide above. [Beilstein 4 IV 327.]

References

[1] C Spagnuolo. “Gel filtration and reactivity of sulphydryl groups of human hemoglobin in concentrated triethylamine hydrochloride solutions.” The Italian journal of biochemistry 21 4 (1972): 221–9.
[2] G. Tian, Qi-Li Yuan, Huanhuan Du. “The Effects of Benzene on the Structure and Properties of Triethylamine Hydrochloride/Chloroaluminate.” Crystals 6 1 (2021).
[3] Zhe Zhang. “Solubility Determination and Model Evaluation of Triethylamine Hydrochloride in Three Binary Mixed Solvents.” Journal of Solution Chemistry 53 10 (2024): 1353–1373.
[4] Junfeng Teng . “Measurement, correlation, and analysis of the solubility of triethylamine hydrochloride in ten pure solvents.” Journal of Molecular Liquids 390 (2023): Article 123040.

Triethylamine hydrochloride synthesis

Synthesis of Triethylamine hydrochloride from Ethylene thiourea

Triethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Triethylamine

Preparation Products

2-(4-Chloromethylpiperidin-1-yl)pyrimidine-5-carboxamide ,97% Triethylenethiophosphoramide 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbaldehyde 2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonyl chloride

Cefotaxime sodium HEPTENOPHOS 1-(5-(Hydroxymethyl)pyrimidin-2-yl)piperidin-4-ol Lisinopril Dihydrate 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxylic acid

2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile (2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidin-5-yl)methanol 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxamide Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate Phosazetim

2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate Ethyl 2-(4-hydroxypiperidin-1-yl)pyrimidine-5-carboxylate 2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine N,O-Bis(trimethylsilyl)acetamide Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)pyrimidine-5-carboxylate

(2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanol 2-Chloropyrimidine-5-carboxylic acid 2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic acid Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate Triazophos

Atracurium besylate 2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxamide (2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanamine

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Triethylamine hydrochloride Suppliers

Global( 594)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21588	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	1497	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from Triethylamine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-31	Triethylamine hydrochloride 554-68-7			0.99		RongNa Biotechnology Co.,Ltd
2026-05-29	Triethylamine hydrochloride 554-68-7		1KG	99%min	20 tons	WUHAN FORTUNA CHEMICAL CO., LTD
2026-05-28	Triethylamine hydrochloride 554-68-7	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD

Triethylamine hydrochloride
554-68-7
0.99
RongNa Biotechnology Co.,Ltd

Triethylamine hydrochloride
554-68-7
$0.00
99%min
WUHAN FORTUNA CHEMICAL CO., LTD

Triethylamine hydrochloride
554-68-7
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

Triethylamine hydrochloride Spectrum

Triethylamine hydrochloride(554-68-7)¹HNMR Triethylamine hydrochloride(554-68-7)¹³CNMR Triethylamine hydrochloride(554-68-7)IR1 Triethylamine hydrochloride(554-68-7)IR2 Triethylamine hydrochloride(554-68-7)Raman

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Tolzaoline bydrochloride TriethylamineHydrochloride,>99% Triethylaminehydrochloride,98% Triethylammoniumchlorid Et3·HCl Triethylamine hydroc TriethylaMine hydrochloride, 99+% 1KG TriethylaMine hydrochloride, 99+% 250GR N,N-Diethylethanaminehydrochloride n,n-diethyl-ethanaminhydrochloride triethylaminemonohydrochloride TriethylaminHydrochlorid triethylaMine hydrogen chloride TriethylaMine hydrochlorid Triethylamine bydrochloride Trimethylamine Hci TriethylaMine hydrochloride >=99.0% (AT) [E3N]HCl Triethylammonium chloride for synthesis TRIETHYLAMINE HYDROCHLORIDE amine,triethyl,hydrochloride Ethanamine,N,N-diethyl-,hydrochloride 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-1H- pyrrolo[3,4-b]pyridin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride Ethanamine, N,N-diethyl-, hydrochloride (1:1) (Triethylamine hydrochloride) (S)-10-(1-aminocyclopropyl)-3-methyl-7-oxo-2,3-dihydro-7H-[1,4] oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride TriEthylAmmonium HydroChloride TriethylamineHydrochloride> Triethylamine hydrochloride ISO 9001：2015 REACH 4-(2-(tert-butylamino)-1-ethoxyethyl)-2-(hydroxymethyl)phenol hydrochloride Ethanamine,N,N-diethyl-,hydrochlorid 8-cyclopentyl-5-methyl-2,6-bis((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride(1:2) triethylammomium chloride Triethylamine Hydrochloride, ≥ 98.5% Triethylamine hydrochloride, 99%(T) Hydrochloride（UnclearStructure） TRIETHYLAMMONIUM CHLORIDE TRIETHYLAMINE HCL 554-68-7 C6H15NHClC6H16ClN C6H15NHCl C2H53NHCl C7H15NxHCl CH3CH23NHCl C6H15NClH C6H18NCl Building Blocks Analytical Chromatography Product Catalog Amine Salts Organic Building Blocks Nitrogen Compounds HPLC Buffers - Solution HPLC HPLC Buffers HPLC HPLC Buffer HPLC Buffers HPLC Buffers - SolutionChromatography/CE Reagents Solution