DISPASE
- CAS No.
- 9068-59-1
- Chemical Name:
- DISPASE
- Synonyms
- DISPASE;CALPAIN;PRONASE E;DISPASE I;danbaimei;DISPASE II;Serratidase;EC: 3.4.24.4;IUB: 3.4.24.6;NEUTRAL PROTEASE
- CBNumber:
- CB0768845
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00287245
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Pronase E | 1.07433 | 5G | $628 |
| Pronase E | 1.07433 | 1G | $175 |
| More product size | |||
| storage temp. | −20°C |
|---|---|
| form | lyophilized powder |
| color | Light yellow to brown |
| PH | 6-7 (20°C, 10g/L in H2O) |
| CAS DataBase Reference | 9068-59-1 |
| UNSPSC Code | 12352204 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H334-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P261-P285-P304+P341-P342+P311-P501 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 22-24-26-36/37 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 STOT SE 3 |
DISPASE Chemical Properties,Uses,Production
Uses
Pronase E (from Streptomyces griseus) 4,000,000 PU/g for biochemistry EC 3.4.24.4. CAS 9036-06-0, pH 6?-?7 (10?g/l, H?O, 20?°C).
General Description
from Streptomyces griseus 4,000,000 PU/g for biochemistry EC 3.4.24.4
Description
Neutral Protease (Dispase®) is isolated from Bacillus polymyxa and is a mild proteolytic enzyme that separates the epidermis from dermis by cleaving the basement membrane zone of the skin while preserving the viability of epithelial sheets. This enzyme is effective at cleaving fibronectin and type IV collagen in the lamina densa of skin. It will not cleave serum albumin, transferrin, laminin, type V collagen, or anchoring fibrils containing type VII collagen. As described in the expired U.S. Patent 4,304,866, Neutral Protease (Dispase®) is activated by metallic ions such as Ca++, Mn++, Mg++, Fe++, Fe+++, and Al+++ and is inhibited by metal-chelating agents such as ethylenediaminetetraacetic acid (EDTA), citric acid, o-phenanthroline, 2,2'-dipyridyl and sodium fluoride, and oxidizing agents such as N-bromosuccinimide (NBS) and iodine. Neutral Protease (Dispase®) is used at various concentrations for tissue dissociation, generally ranging from 0.6 to 2.4 U/ml for various time points depending on the desired effect. Concentrations higher than 2.4 U/ml are not recommended.
Source
B. polymyxa
DISPASE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 +86-13986145403; | info@fortunachem.com | China | 6011 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19781 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
View Lastest Price from DISPASE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-28 | Dispase
9068-59-1
|
US $0.00-0.00 / g | 1g | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-11-02 | DISPASE
9068-59-1
|
US $127.00 / KG | 1KG | 99 | 52000T | Baoji Guokang Healthchem co.,ltd | |
 |
2020-11-16 | DISPASE
9068-59-1
|
US $40.00 / KG | 100KG | 99% | 5000KG | Longyan Tianhua Biological Technology Co., Ltd |
