Sirukumab
- CAS No.
- 1194585-53-9
- Chemical Name:
- Sirukumab
- Synonyms
- Sirukumab;Sirukumab (anti-IL-6);Research Grade Sirukumab;Research Grade Sirukumab(DHC15803)
- CBNumber:
- CB08080842
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 640443FU93 |
| ATC code | L04AC15 |
Sirukumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0621066 | Sirukumab 96.83% | 1194585-53-9 | 1mg | $314 | 2026-06-04 | Buy |
| ChemScene | CS-0621066 | Sirukumab 96.83% | 1194585-53-9 | 5mg | $845 | 2026-06-04 | Buy |
| ChemScene | CS-0621066 | Sirukumab 96.83% | 1194585-53-9 | 10mg | $1246 | 2026-06-04 | Buy |
| aablocks | AA0294S2 | Sirukumab ≥95%(SDS-PAGE&SEC-HPLC) | 1194585-53-9 | 1mg | $532 | 2026-06-02 | Buy |
| aablocks | AA0294S2 | Sirukumab ≥95%(SDS-PAGE&SEC-HPLC) | 1194585-53-9 | 5mg | $1740 | 2026-06-02 | Buy |
Sirukumab Chemical Properties, Uses, Production
Uses
Sirukumab (CNTO-136) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody. Sirukumab binds to IL6, preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis[1][2].
References
[1] Brad H Rovin, et al. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Treatment With Sirukumab (CNTO 136) in Patients With Active Lupus Nephritis. Arthritis Rheumatol. 2016 Sep;68(9):2174-83. DOI:10.1002/art.39722
[2] Bartoli F, et al. Sirukumab for the treatment of rheumatoid arthritis: update on sirukumab, 2018[J]. Expert Review of Clinical Immunology, 2018, 14(7): 539-547. DOI:10.1080/1744666X.2018.1487291
Sirukumab Preparation Products And Raw materials
Raw materials
Preparation Products
Sirukumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
