SAUCHINONE
- CAS No.
- 177931-17-8
- Chemical Name:
- SAUCHINONE
- Synonyms
- AI300896;AI3-00896;AI3 00896;SAUCHINONE;Sauchinone-RM;Sauchinone >=98% (HPLC);Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill;(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;(5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro- 5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one;(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
- CBNumber:
- CB0821863
- Molecular Formula:
- C20H20O6
- Molecular Weight:
- 356.37
- MDL Number:
- MFCD08702698
- MOL File:
- 177931-17-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Sauchinone ≥98% (HPLC) | SML0783 | 5mg | $144 |
| Sauchinone ≥98% (HPLC) | SML0783 | 25mg | $376 |
| Sauchinone ≥98% | 19577 | 1mg | $32 |
| Sauchinone ≥98% | 19577 | 5mg | $109 |
| Sauchinone ≥98% | 19577 | 10mg | $199 |
| More product size | |||
| Melting point | 224-226℃ |
|---|---|
| Boiling point | 498.1±45.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| InChI | 1S/C20H20O6/c1-9-3-11-13(21)5-17-20(25-8-24-17)19(11)18(10(9)2)12-4-15-16(23-7-22-15)6-14(12)26-20/h4-6,9-11,18-19H,3,7-8H2,1-2H3/t9-,10+,11+,18+,19+,20+/m1/s1 |
| InChIKey | GMTJIWUFFXGFHH-WPAOEJHSSA-N |
| SMILES | O=C(C=C1OCO2)[C@]3([H])C[C@@H](C)[C@H](C)[C@@]4([H])C5=CC6=C(OCO6)C=C5O[C@]12[C@]43[H] |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29329990 |
| Storage Class | 11 - Combustible Solids |
SAUCHINONE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0783 | Sauchinone ≥98% (HPLC) | 177931-17-8 | 5mg | $144 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML0783 | Sauchinone ≥98% (HPLC) | 177931-17-8 | 25mg | $376 | 2025-07-31 | Buy |
| Cayman Chemical | 19577 | Sauchinone ≥98% | 177931-17-8 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19577 | Sauchinone ≥98% | 177931-17-8 | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 19577 | Sauchinone ≥98% | 177931-17-8 | 10mg | $199 | 2024-03-01 | Buy |
SAUCHINONE Chemical Properties,Uses,Production
Chemical Properties
Yellow crystalline powder, easily soluble in methanol and ethyl acetate, derived from Saururus chinensis.
Uses
Sauchinone is a lignan first isolated from the aerial parts of S. chinensis, a plant used in Asian medicine for its anti-inflammatory, anti-angiogenic, and anti-nociceptive activities. Sauchinone has numerous effects on isolated cells, including blocking NF-κB activation in LPS-stimulated macrophages, inducing heme oxygenase-1 transcription in endothelial cells, and attenuating oxidative-stress-induced damage in myoblasts. Sauchinone is extensively metabolized in vivo, but intraperitoneal administration significantly reduces myocardial infarct size induced by ischemia/reperfusion in mice.
Biological Activity
Sauchinone is an anti-inflammatory and antioxidant lignan isolated from Saururus chinensis a medical plant used for the treatment of fever, jaundice, oedema and inflammatory disease in oriental folk medicine. Sauchinone inhibits LPS-inducible iNOS (NOS II), TNF-α and COX-2 expression in macrophages through suppression of IKBα phosphorylation. It appears th at sauchinone protects against myocardial ischemia/reperfusion injury by inhibition of p28 phosphorylation.
SAUCHINONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
View Lastest Price from SAUCHINONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | Sauchinone
177931-17-8
|
US $0.00-0.00 / mg | 99.12% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Sauchinone
177931-17-8
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-06 | SAUCHINONE
177931-17-8
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
-
- Sauchinone
177931-17-8
- US $0.00-0.00 / mg
- 99.12%
- TargetMol Chemicals Inc.
-
- Sauchinone
177931-17-8
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- SAUCHINONE
177931-17-8
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
