Sodium formaldehydesulfoxylate dihydrate
- CAS No.
- 6035-47-8
- Chemical Name:
- Sodium formaldehydesulfoxylate dihydrate
- Synonyms
- RONGALITE;SODIUM FORMALDEHYDE SULPHOXYLATE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM HYDROXYMETHANESULFINATE DIHYDRATE;RONGALIT;RONGALITE C;FORMALDEHYDE SODIUM SULFOXYLATE;SODIUM HYDROXYMETHYLSULFINATE;SODIUM FORMALDEHYDESULFOXALATE;Sodium dihydrate hydroxymethanesulfinate
- CBNumber:
- CB0853952
- Molecular Formula:
- CH7NaO4S
- Molecular Weight:
- 138.11
- MDL Number:
- MFCD00040426
- MOL File:
- 6035-47-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 64-68 °C(lit.) |
|---|---|
| Density | 1.8 g/cm3 (20℃) |
| bulk density | 950kg/m3 |
| vapor pressure | 2.68 hPa (20 °C) |
| storage temp. | Store below +30°C. |
| solubility | alcohol: slightly soluble(lit.) |
| form | powder to crystal |
| color | White to Almost white |
| PH | 9.5-10.5 (100g/l, H2O, 20℃) |
| Water Solubility | H2O: 50mg/mL, clear, colorless |
| InChI | InChI=1S/CH4O3S.Na.H2O.H/c2-1-5(3)4;;;/h2H,1H2,(H,3,4);;1H2; |
| InChIKey | GNKDHZHOQAELOA-UHFFFAOYSA-N |
| SMILES | S(O)(=O)CO.[NaH].O |
| CAS DataBase Reference | 6035-47-8(CAS DataBase Reference) |
| FDA UNII | SQ4705447D |
| UNSPSC Code | 12352107 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H341-H361d |
| Precautionary statements | P201-P308+P313 |
| PPE | Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 31-68 |
| Safety Statements | 24/25-36/37 |
| WGK Germany | 3 |
| RTECS | PB0390000 |
| HS Code | 28311000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Muta. 2 Repr. 2 |
| Toxicity | LD50 orally in Rabbit: 6400 mg/kg |
Sodium formaldehydesulfoxylate dihydrate price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilisedwithsodiumcarbonate)forsynthesis | 6035-47-8 | 100g | $38.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilisedwithsodiumcarbonate)forsynthesis | 6035-47-8 | 1kg | $57.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.17068 | Sodium formaldehydesulfoxylate hydrate stabilized with sodium carbonate | 6035-47-8 | 1kg | $271 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilisedwithsodiumcarbonate)forsynthesis | 6035-47-8 | 5kg | $288 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.17068 | Sodium formaldehydesulfoxylate hydrate stabilized with sodium carbonate | 6035-47-8 | 25kg | $4360 | 2026-04-30 | Buy |
Sodium formaldehydesulfoxylate dihydrate Chemical Properties, Uses, Production
Chemical Properties
white crystalline powder
Chemical Properties
When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.
Uses
Pharmaceutic aid (preservative).
Uses
Sodium hydroxymethanesulfinate dihydrate is a versatile reagent that can be used for a wide range of organic transformations such as:
- A SO2-2anion source for the preparation of sulfones and sultines.
- Debromination of vicinal dibromoalkanes.
- Reductive dehalogenation of aldehydes and ketones.
Production Methods
Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.
General Description
Oxidation reation of hydroxymethanesulfinic acid with chlorite has been studied in the pH range 4-8. It is a sulfur-containing reducing agent.
Pharmaceutical Applications
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.
Safety
The toxicological properties of sodium formaldehyde sulfoxylate
have not been fully investigated. However, it is used in the
formulation of injection products at a level to 0.1% w/v in the
final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by
ingestion, and when heated to decomposition it emits toxic fumes
of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg
storage
Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).
Incompatibilities
Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.
Regulatory Status
Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium formaldehydesulfoxylate dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dexin chemical (Shandong) Co. , Ltd. | 18815338815 | dexinhuaxue@163.com | China | 152 | 58 |
| Jinan Leihe Trading Co., Ltd | 0531-88773819 13305412878 | 849314057@qq.com | China | 108 | 58 |
| Tenghong (Shandong) New Material Co., Ltd | 1555-2555846 18265060865 | 1277177917@qq.com | China | 2793 | 58 |
| Jinan Rongxin Chemical Technology Co., Ltd | 13365316808 15215418789 | 1726419589@qq.con | China | 59 | 58 |
| shandongxinheng | 152-15269160605-0605 15269160605 | 15269160605@163.com | China | 986 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
View Latest Price from Sodium formaldehydesulfoxylate dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Sodium formaldehydesulfoxylate dihydrate
6035-47-8
|
$10.00 | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-09-09 | Sodium Formaldehyde Sulphoxylate
6035-47-8
|
$50.00-2000.00 | 1000kg | 98% min, 99% min | 5000MT per year | Wuxi High Mountain Hi-tech Development Co.,Ltd. | |
 |
2026-09-02 | Sodium formaldehydesulfoxylate dihydrate
6035-47-8
|
$1.00-8.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd |
-
- Sodium formaldehydesulfoxylate dihydrate
6035-47-8
- $10.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Sodium Formaldehyde Sulphoxylate
6035-47-8
- $50.00-2000.00
- 98% min, 99% min
- Wuxi High Mountain Hi-tech Development Co.,Ltd.
-
- Sodium formaldehydesulfoxylate dihydrate
6035-47-8
- $1.00-8.00
- 99%
- Henan Fengda Chemical Co., Ltd
