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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine structure

CAS No.: 129421-32-5

Chemical Name:: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

Synonyms: 2,3-Dihydro-1,4-Dioxino[2,3-b];2H,3H-[1,4]dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;Benzoicacid,3-bromo-8-methoxy-,hydrazide;5-Benzofuransulfonylchloride,2,8-dihydro-;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New;1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI);2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH

CBNumber:: CB0854858

Molecular Formula:: C7H7NO2

Molecular Weight:: 137.14

MDL Number:: MFCD09743547

MOL File:: 129421-32-5.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:44

Product description	Number	Pack Size	Price
2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine Aldrich	ADE000017	1g	$817
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	D453978	10mg	$45
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	D453978	100mg	$240
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	FD106499	1g	$250
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	FD106499	250mg	$100
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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Properties

Boiling point	234°C
Density	1.229
Flash point	84°C
storage temp.	Sealed in dry,Room Temperature
form	solid
pka	4.93±0.20(Predicted)
color	Off-white
InChI	InChI=1S/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2
InChIKey	QWQZJEXJTYAPGE-UHFFFAOYSA-N
SMILES	C12OCCOC1=CC=CN=2
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HazardClass	IRRITANT
HS Code	2934999090

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000017	2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine Aldrich	129421-32-5	1g	$817	2025-07-31	Buy
TRC	D453978	2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	129421-32-5	10mg	$45	2021-12-16	Buy
TRC	D453978	2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	129421-32-5	100mg	$240	2021-12-16	Buy
Biosynth Carbosynth	FD106499	2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	129421-32-5	1g	$250	2021-12-16	Buy
Biosynth Carbosynth	FD106499	2,3-Dihydro-1,4-dioxino[2,3-b]pyridine	129421-32-5	250mg	$100	2021-12-16	Buy

Product number	Packaging	Price	Buy
ADE000017	1g	$817	Buy
D453978	10mg	$45	Buy
D453978	100mg	$240	Buy
FD106499	1g	$250	Buy
FD106499	250mg	$100	Buy

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Chemical Properties,Uses,Production

Synthesis

16867-04-2

106-93-4

129421-32-5

a-1) Synthesis of 2,3-dihydro-[1,4]dioxohexa[2,3-b]pyridine 2,3-Dihydroxypyridine (2.22 g, 20.0 mmol) was dissolved in N,N-dimethylformamide (100 mL) and potassium carbonate (5.52 g, 40.0 mmol) was added at room temperature. After stirring for 5 min, 1,2-dibromoethane (2.6 mL, 30.0 mmol) was added slowly and dropwise at the same temperature. The reaction mixture was heated to 90 °C and the reaction was stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to remove the insoluble salt. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was dissolved in ethyl acetate. The suspension was filtered, the filter cake was washed with ethyl acetate, the filtrates were combined and concentrated again under reduced pressure to give 2,3-dihydro-1,4-dioxo[2,3-b]pyridine (157 mg, 5.7% yield) as a colorless oil. 1H-NMR (CDCl3) δ: 4.26-4.28 (2H, m), 4.42-4.44 (2H, m), 6.94 (1H, dd, J = 5.6, 7.6 Hz), 7.28 (1H, dd, J = 1.2, 7.6 Hz), 7.69 (1H, dd, J = 1.2, 5.6 Hz).

References

[1] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 49
[2] Patent: WO2015/42397, 2015, A1. Location in patent: Paragraph 000788

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

2,3-Dihydroxypyridine 1,2-Dibromoethane 1-Bromo-2-chloroethane N,N-Dimethylformamide Potassium carbonate

Preparation Products

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Suppliers

Global( 114)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29796	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	7825	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
GL Biochem (Shanghai) Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Shaanxi Dideu Medichem Co. Ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58

View Lastest Price from 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-06-25	2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2019-12-20	2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5	US $1.00 / KG	1KG	99%	1000KGS	Career Henan Chemical Co

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
129421-32-5
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
129421-32-5
US $1.00 / KG
99%
Career Henan Chemical Co

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Spectrum

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(129421-32-5)¹HNMR

129421-32-5(2,3-Dihydro-1,4-dioxino[2,3-b]pyridine)Related Search:

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1of3

1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 2,3-Dihydro-1,4-Dioxino[2,3-b] 1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI) 2H,3H-[1,4]dioxino[2,3-b]pyridine 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH Benzoicacid,3-bromo-8-methoxy-,hydrazide 5-Benzofuransulfonylchloride,2,8-dihydro- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New 129421-32-5 PYRIDINE Heterocycle-Pyridine series