Letosteine
- CAS No.
- 53943-88-7
- Chemical Name:
- Letosteine
- Synonyms
- Visoctiol;Viscotiol;Letosteine;Letosteine, 10 mM in DMSO;2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid;2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid;4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-;2-[2-(2-Ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid
- CBNumber:
- CB0875396
- Molecular Formula:
- C10H17NO4S2
- Molecular Weight:
- 279.38
- MDL Number:
- MOL File:
- 53943-88-7.mol
| Product description | Number | Pack Size | Price |
| Letosteine | L330103 | 100mg | $50 |
| Letosteine | L330103 | 1g | $220 |
| 2-[2-(2-ETHOXY-2-OXOETHYL)SULFANYLETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID 95.00% | API0010497 | 1G | $240.45 |
| Letosteine | J11158 | 100mg | $298 |
| Letosteine | J11158 | 5mg | $49 |
| Melting point | 142° |
|---|---|
| Boiling point | 470.0±45.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Dichloromethane (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 2.05±0.40(Predicted) |
| color | White to Pale Yellow |
| CAS DataBase Reference | 53943-88-7 |
| FDA UNII | 6MVF9U95DW |
| ATC code | R05CB09 |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
Letosteine price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | L330103 | Letosteine | 53943-88-7 | 100mg | $50 | 2021-12-16 | Buy |
| TRC | L330103 | Letosteine | 53943-88-7 | 1g | $220 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010497 | 2-[2-(2-ETHOXY-2-OXOETHYL)SULFANYLETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID 95.00% | 53943-88-7 | 1G | $240.45 | 2021-12-16 | Buy |
| AK Scientific | J11158 | Letosteine | 53943-88-7 | 100mg | $298 | 2021-12-16 | Buy |
| AK Scientific | J11158 | Letosteine | 53943-88-7 | 5mg | $49 | 2021-12-16 | Buy |
Letosteine Chemical Properties,Uses,Production
Uses
Letostan is a cyclic cysteine derivative with mucolytic properties, clinically used to treat obstructive bronchopulmonary diseases, including chronic bronchitis, emphysema, and asthma.
Originator
Viscotiol,Carlo Erba,France,1979
Definition
ChEBI: A dicarboxylic acid monoester that is the monoethyl ester of 2-{2-[(carboxymethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid. A mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Manufacturing Process
In an Erlenmeyer flask placed in an ice bath, and under a well-ventilated
hood, a solution of 0.1 mol of acrolein in 100 ml of ether was introduced, With
the aid of a bromine ampoule, 0.1 mol (= 11 ml) of the ethyl ester of
thioglycolic acid containing 0.5 ml of triethylamine was added drop by drop.
One hour after completion of the addition, there was added 0.1 mol (15.6 g)
of chlorhydrate of cysteine in alcoholic solution. The chlorhydrate of the
expected derivative, which appeared in the form of a thick oil, was
precipitated by addition of 0.1 mol (10 g) of potassium acetate in aqueous
solution. The abundant precipitate obtained was filtered and washed in water
and ether. The product was recrystallized in a minimum of absolute alcohol.
Therapeutic Function
Mucolytic
Letosteine Preparation Products And Raw materials
Letosteine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49976 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32436 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shandong Zhishang New Material Co., Ltd. | +8617653113209 | sales002@sdzschem.com | China | 3049 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49937 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | 3684455296@qq.com | China | 9300 | 58 |
View Lastest Price from Letosteine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-13 | Letosteine
53943-88-7
|
US $30.00-77.00 / mg | 99.26% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-09 | Letosteine
53943-88-7
|
US $2.00 / KG | 1KG | 98% | 1kg, 5kg ,50kg | Career Henan Chemical Co |
-
- Letosteine
53943-88-7
- US $30.00-77.00 / mg
- 99.26%
- TargetMol Chemicals Inc.
-
- Letosteine
53943-88-7
- US $2.00 / KG
- 98%
- Career Henan Chemical Co
