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clofedanol

clofedanol structure

CAS No.: 791-35-5

Chemical Name:: clofedanol

Synonyms: Dencyl;clofedano;Tussistop;clofedanol;Calmotusin;NSC 113595;Chlofedanol;Clophedianol;CHLOPHENDIANOL;Clophedianol base

CBNumber:: CB0875699

Molecular Formula:: C17H20ClNO

Molecular Weight:: 289.7998

MDL Number:: MFCD00866840

MOL File:: 791-35-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 22:57:17

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clofedanol Properties

Melting point	120°
Boiling point	429.8±45.0 °C(Predicted)
Density	1.148±0.06 g/cm3(Predicted)
pka	13.03±0.29(Predicted)
CAS DataBase Reference	791-35-5
FDA UNII	42C50P12AP
ATC code	R05DB10

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P264-P270-P301+P310-P321-P330-P405-P501
Toxicity	LD50 i.v. in mice: 70 mg/kg (Lorenz)
REACH Registrations	Active

clofedanol price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
IsoSciences	13420	Chlophedianol-[13C6] ≥98%	791-35-5	1mg	$217	2021-12-16	Buy
American Custom Chemicals Corporation	API0009164	CHLOPHEDIANOL 95.00%	791-35-5	250MG	$727.65	2021-12-16	Buy
American Custom Chemicals Corporation	API0009164	CHLOPHEDIANOL 95.00%	791-35-5	1G	$825.3	2021-12-16	Buy

Product number	Packaging	Price	Buy
13420	1mg	$217	Buy
API0009164	250MG	$727.65	Buy
API0009164	1G	$825.3	Buy

clofedanol Chemical Properties, Uses, Production

Originator

Detigon,Bayer,W. Germany,1958

Uses

(±)-Chlophedianol is an inhalation eutectic compound, used for treatment of respiratory diseases.Also, used in preparation of Deuterated morphine derivatives useful in treatment of pain or as as antitussive agents with reduced risk of possibility of drug abuse.

Definition

ChEBI: Clofedanol is a diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain. It has a role as an antitussive. It is a diarylmethane and a tertiary amino compound. It is a conjugate base of a clofedanol(1+).

Manufacturing Process

This compound may be produced by reacting o-chlorobenzophenone with acetonitrile in the presence of sodium amide or another strongly basic condensing agent, to form the nitrile of beta-phenyl-beta-o-chlorophenyl-hydracrylic acid, which is then hydrogenated to yield 1-phenyl-1-o-chlorophenyl-3-aminopropanol-1. The latter intermediate compound is subsequently dimethylated with an agent such as methyl sulfate to provide the desired end product 1-o-chlorophenyl-1-phenyl-3-dimethylaminopropanol.

Therapeutic Function

Antitussive

clofedanol Preparation Products And Raw materials

Raw materials

Dimethyl sulfate Sodium amide Hydrogen (2-Chlorophenyl)phenyl-methanone Acetonitrile

Preparation Products

clofedanol Suppliers

Global Suppliers ( 35)

Supplier	Tel	Email	Country	ProdList	Advantage
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-83725681-603		China	4484	50
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Chengdu Saint - Kay Biotechnology Co., Ltd.	028-85157043 15882256948	676046971@qq.com	China	4183	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Wuhan Huibaixin Technology Co., Ltd.	17364282875	hbx66@qq.com	CHINA	1540	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39866	58
Wuhan pengyin Pharmaceutical Co., Ltd	13163333255	1939328613@qq.com	China	392	58

Supplier	Advantage
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
Hangzhou Sage Chemical Co., Ltd.	58
BOC Sciences	65
Chengdu Saint - Kay Biotechnology Co., Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Wuhan Huibaixin Technology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Wuhan pengyin Pharmaceutical Co., Ltd	58

View Latest Price from clofedanol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-21	Clofedanol 791-35-5	$1520.00-2500.00			10g	TargetMol Chemicals Inc.
	2019-07-14	clofedanol 791-35-5	$8.80	1KG	97%-99%	100kg	Career Henan Chemical Co

Clofedanol
791-35-5
$1520.00-2500.00
TargetMol Chemicals Inc.

clofedanol
791-35-5
$8.80
97%-99%
Career Henan Chemical Co

791-35-5 (clofedanol) Related Search:

2-Chloro-alpha-[2-dimethylaminoethyl]benzhydrol hydrochloride Trimethylolpropane Robenidine hydrochloride Dextromethorphan Cimetidine

Ranitidine Daptomycin Atropine 3-Dimethylamino-1-propanol

1of2

1-(2-chlorophenyl)-3-dimethylamino-1-phenylpropan-1-ol clofedanol clofedano CHLOPHENDIANOL 1-o-Chlorophenyl-1-phenyl-3-dimethylamino-1-propanol 1-o-Chlorophenyl-3-dimethylamino-1-phenylpropan-1-ol 1-Phenyl-1-(o-chlorophenyl)-3-dimethylaminopropanol 1-Phenyl-1-o-chlorophenyl-3-(dimethylamino)-1-propanol 2-Chloro-α-(2-dimethylaminoethyl)benzhydrol Benzenemethanol, 2-chloro-α-[2-(dimethylamino)ethyl]-α-phenyl- Benzhydrol, 2-chloro-α-[2-(dimethylamino)ethyl]- (6CI, 7CI, 8CI) Calmotusin NSC 113595 Tussistop α-(Dimethylaminoethyl)-o-chlorobenzhydrol Chlophedianol (base and/or unspecified salts) CLOFEDANOL(CHLOPHEDIANOL) Chlofedanol .alpha.-(Dimethylaminoethyl)-o-chlorobenzhydrol 2-Chloro-.alpha.-(2-dimethylaminoethyl)benzhydrol Benzenemethanol, 2-chloro-.alpha.-[2-(dimethylamino)ethyl]-.alpha.-phenyl- Benzhydrol, 2-chloro-.alpha.-[2-(dimethylamino)ethyl]- Clophedianol base Dencyl Clophedianol Chlophedianol-13C6 clofedanol USP/EP/BP 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenyl-1-propanol 791-35-5