ChemicalBook >> CAS DataBase List >>4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]-

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]-

CAS No.
32887-03-9
Chemical Name:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]-
Synonyms
Selexid;Melysin;PIVMECILLINAM HCL;Amidinocillin Pivoxil;FL-1039 hydrochloride;PIVMECILLINUMHYDROCHLORIDE;Pivmecillinam-d9 Hydrochloride;Pivmecillinam hydrochloride CRS;Amdinocillin pivoxil hydrochloride;PIVMECILLINAM HYDROCHLORIDE USP/EP/BP
CBNumber:
CB0919214
Molecular Formula:
C21H34ClN3O5S
Molecular Weight:
476.02976
MDL Number:
MOL File:
32887-03-9.mol
MSDS File:
SDS
Last updated:2026-02-02 18:10:39
Product description Number Pack Size Price
Pivmecillinam hydrochloride European Pharmacopoeia (EP) Reference Standard P2152000 100 mg $164
Pivmecillinam hydrochloride European Pharmacopoeia (EP) Reference Standard P2152000 p2152000 $153
Pivmecillinam hydrochloride P550700 500mg $1540
Pivmecillinam hydrochloride ≥98.0% CS-4222 100mg $336
Pivmecillinam hydrochloride 3975AH 100mg $406
More product size

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]- Properties

Melting point 172-173°
alpha D20 +219° (c = 1 in 0.1N HCl)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Freely soluble in water, in anhydrous ethanol and in methanol, slightly soluble in acetone.
form Solid
color White to off-white
CAS DataBase Reference 32887-03-9
FDA UNII 48FX7N21H2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]- price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P2152000 Pivmecillinam hydrochloride European Pharmacopoeia (EP) Reference Standard 32887-03-9 100 mg $164 2025-07-31 Buy
Sigma-Aldrich P2152000 Pivmecillinam hydrochloride European Pharmacopoeia (EP) Reference Standard 32887-03-9 p2152000 $153 2024-03-01 Buy
TRC P550700 Pivmecillinam hydrochloride 32887-03-9 500mg $1540 2021-12-16 Buy
ChemScene CS-4222 Pivmecillinam hydrochloride ≥98.0% 32887-03-9 100mg $336 2021-12-16 Buy
AK Scientific 3975AH Pivmecillinam hydrochloride 32887-03-9 100mg $406 2021-12-16 Buy
Product number Packaging Price Buy
P2152000 100 mg $164 Buy
P2152000 p2152000 $153 Buy
P550700 500mg $1540 Buy
CS-4222 100mg $336 Buy
3975AH 100mg $406 Buy

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]- Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Pivmecillinam is an orally active prodrug of Amdinocillin (A576300), an broad spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2.

in vivo

Pivmecillinam (0.5 and 1 mg per mouse, subcutaneous injection, three times daily for four days) can effectively inhibit urinary tract infections caused by multidrug-resistant E. coli in a mouse model of urinary tract infection induced by catheter injection of E. coli[4].

Animal Model:Mouse urinary tract infection (UTI) model (OF1 female mice were inoculated with approximately 109 CFU/mL E. coli bacterial suspension through a catheter)[4]
Dosage:0.5 and 1 mg/mouse
Administration:Subcutaneous injection (s.c.), three times daily for 4 days
Result:Significantly reduced the number of E. coli strains in the urine, bladder, and kidneys, especially in the urine.

IC 50

β-lactam

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]- Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 83)Suppliers
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Aladdin Scientific
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View Lastest Price from 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pivmecillinam hydrochloride pictures 2026-02-01 Pivmecillinam hydrochloride
32887-03-9
US $30.00-73.00 / mg 99.36% 10g TargetMol Chemicals Inc.
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha,6beta)]- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (2S,5R,6R)- (9CI) 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2a,5a,6b)]- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, hydroxymethyl ester pivalate (ester), monohydrochloride, (+)- (8CI) Selexid PIVMECILLINUMHYDROCHLORIDE Amidinocillin Pivoxil Melysin PIVMECILLINAM HCL Pivmecillinam hydrochloride (Amdinocillin pivoxil hydrochloride) 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, [2S-(2alpha,5alpha Pivmecillinam-d9 Hydrochloride Amdinocillin pivoxil hydrochloride AMDINOCILLIN PIVOXIL HYDROCHLORIDE;SELEXID 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid FL-1039 hydrochloride Pivmecillinam hydrochloride CRS (2S,5R,6R)-(pivaloyloxy)methyl 6-((azepan-1-ylmethylene)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride PIVMECILLINAM HYDROCHLORIDE EPP(CRM STANDARD) USP/EP/BP PIVMECILLINAM HYDROCHLORIDE USP/EP/BP 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, hydrochloride (1:1), (2S,5R,6R)- (Pivaloyloxy)methyl (2S,5R,6R)-6-((azepan-1-ylmethylene)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride Inhibitor,Antibiotic,FL 1039,FL1039,Pivmecillinam,Pivmecillinam hydrochloride,Bacterial,FL-1039,inhibit Pivmecillinam hydrochloride, 10 mM in DMSO 32887-03-9 C21H33N3O5SHCl C21H34ClN3O5S