Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER Structure
4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER structure
CAS No.
432022-88-3
Chemical Name:
4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER
Synonyms
4-bromo-3,5-dimethyl benzoate;Mehtyl 4-broMo-3,5-diMethylbenzoate;Methyl 4-Bromo-3, 5-Dimethyl Benzoat;4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER;BENZOIC ACID, 4-BROMO-3,5-DIMETHYL-, METHYL ESTER
CBNumber:
CB11010595
Molecular Formula:
C10H11BrO2
Molecular Weight:
243.1
MDL Number:
MFCD09833419
MOL File:
432022-88-3.mol
MSDS File:
SDS
Last updated:2026-06-29 20:13:11
Product description Number Pack Size Price
Methyl 4-bromo-3,5-dimethylbenzoate 97% AS110816 1g $48
Methyl 4-bromo-3,5-dimethylbenzoate 97% AS110816 5g $197
Methyl 4-bromo-3,5-dimethylbenzoate 97% AS110816 25g $948
Methyl 4-bromo-3,5-dimethylbenzoate 201186 1.00g $1708
Methyl 4-bromo-3,5-dimethylbenzoate 201186 25.00g $7789
More product size
Request For Quotation

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER Properties

Boiling point 310.8±37.0 °C(Predicted)
Density 1.380±0.06 g/cm3(Predicted)
storage temp. Store at room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color Off-White to Pale Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS110816 Methyl 4-bromo-3,5-dimethylbenzoate 97% 432022-88-3 1g $48 2026-06-04 Buy
Activate Scientific AS110816 Methyl 4-bromo-3,5-dimethylbenzoate 97% 432022-88-3 5g $197 2026-06-04 Buy
Activate Scientific AS110816 Methyl 4-bromo-3,5-dimethylbenzoate 97% 432022-88-3 25g $948 2026-06-04 Buy
Matrix Scientific 201186 Methyl 4-bromo-3,5-dimethylbenzoate 432022-88-3 1.00g $1708 2026-05-18 Buy
Matrix Scientific 201186 Methyl 4-bromo-3,5-dimethylbenzoate 432022-88-3 25.00g $7789 2026-05-18 Buy
Product number Packaging Price Buy
AS110816 1g $48 Buy
AS110816 5g $197 Buy
AS110816 25g $948 Buy
201186 1.00g $1708 Buy
201186 25.00g $7789 Buy

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER Chemical Properties,Uses,Production

Uses

Methyl 4-Bromo-3,5-dimethylbenzoate is a useful reagent for the preparation of benzylaminopyrazinylcyclopropanecarboxylic acid derivatives for use as GPR40 receptor activity modulators.

Synthesis

Methanol

67-56-1

2-chloro-5-nitropyrimidine

400822-47-1

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER

432022-88-3

To a 250 mL round-bottomed flask was added 4-bromo-3,5-dimethylbenzaldehyde (4.0 g, 19 mmol), methanol (100 mL) and potassium iodide (623 mg, 3.8 mmol). The reaction mixture was stirred at 50 °C, followed by slow dropwise addition of tert-butyl hydroperoxide (3.9 mL, 70% aqueous solution, 28 mmol) over 30 min. After the dropwise addition, the reaction mixture was heated to reflux for 24 hours. After completion of the reaction, it was cooled to room temperature and the reaction was quenched by the addition of saturated aqueous sodium thiosulfate. The reaction mixture was extracted with ethyl acetate and the organic phase was dried with anhydrous sodium sulfate and subsequently concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using petroleum ether/ethyl acetate (15:1, v/v) as eluent to afford methyl 4-bromo-3,5-dimethylbenzoate as a white solid (3.8 g, 84% yield).1H NMR (400 MHz, CDCl3) δ 7.73 (s, 2H), 3.90 (s, 3H), 2.46 (s, 6H).

References

[1] Dyes and Pigments, 2018, vol. 155, p. 323 - 331

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER synthesis

67-56-1
400822-47-1
432022-88-3
Synthesis of 4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER from Methanol and 2-chloro-5-nitropyrimidine

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

2-chloro-5-nitropyrimidine 4-AMINO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER 2,5-DIBROMO-M-XYLENE Methanol tert-Butyl hydroperoxide
2,4,6-Trimethybromombenzene

1of2

Preparation Products

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER Suppliers

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Fuxin Pharmaceutical 		+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58
Changzhou Anxuan Chemical Co., Ltd 		+86-0519-89882563 +86-18961279162 andy@anxuanchem.com China 4326 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +86-18949823763 sales@tnjchem.com China 25333 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +8619957148339 market18@leapchem.com China 24569 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +86-13336024896 CB@aromsyn.com China 19176 58
Nanjing Fred Technology Co., Ltd 		+86-25-84696168 +86-15380713688 Austin@fredbio.com China 2428 58
Aladdin Scientific 		tp@aladdinsci.com United States 54746 58
Shaanxi Dideu New Materials Co. Ltd 		18192503167 1036@dideu.com China 13183 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Fuxin Pharmaceutical 		58
Win-Win chemical CO., Limited 		58
Changzhou Anxuan Chemical Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Aromsyn Co., Ltd. 		58
Nanjing Fred Technology Co., Ltd 		58
Aladdin Scientific 		58
Shaanxi Dideu New Materials Co. Ltd 		58

View Lastest Price from 4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl4-bromo-3,5-dimethylbenzoate pictures 2026-06-30 Methyl4-bromo-3,5-dimethylbenzoate
432022-88-3
 1KG 98% 20Tons Shaanxi Dideu New Materials Co. Ltd

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER Spectrum

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER(432022-88-3)1HNMR

432022-88-3(4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER)Related Search:

p-Toluic acid 4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER 4-Bromo-3-methylbenzoic acid Methyl 4-bromo-3-methylbenzoate (4-BROMO-3-METHYLPHENYL)METHANOL
2-chloro-5-nitropyrimidine

1of2

4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER BENZOIC ACID, 4-BROMO-3,5-DIMETHYL-, METHYL ESTER Mehtyl 4-broMo-3,5-diMethylbenzoate Methyl 4-Bromo-3, 5-Dimethyl Benzoat 4-bromo-3,5-dimethyl benzoate 432022-88-3