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7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide

7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide structure

CAS No.: 60656-76-0

Chemical Name:: 7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide

Synonyms: Midazolam Impurity;Midazolam Impurity 11;Midazolam Impurity 26;MIDAZOLAM NITROMETHYLENE COMPOUND;7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide;7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide;7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide;7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide;1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide;7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

CBNumber:: CB11230968

Molecular Formula:: C16H11ClFN3O3

Molecular Weight:: 347.73

MDL Number:

MOL File:: 60656-76-0.mol

Last updated:2026-09-12 18:48:36

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7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide Properties

Melting point	240-243 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
Boiling point	539.7±60.0 °C(Predicted)
Density	1.49±0.1 g/cm3(Predicted)
pka	-1.18±0.20(Predicted)
InChI	InChI=1S/C16H11ClFN3O3/c17-10-5-6-15-13(7-10)16(12-3-1-2-4-14(12)18)20(22)8-11(19-15)9-21(23)24/h1-7,9,19H,8H2
InChIKey	YFNLLWWUWXVJOM-UHFFFAOYSA-N
SMILES	N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=[N+]([O-])CC1=C[N+]([O-])=O

7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide Chemical Properties,Uses,Production

Uses

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.

7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide Suppliers

Global( 37)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BJBXSW	18822637905 15801565083	361766070@qq.com	China	163	58
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9883	50
Shanghai Haozhixiang Biotechnology Co., Ltd	526763801 13301653310	526763801@qq.com	China	7580	55
Shanghai Rechem science Co., Ltd.	021-31433387 15618786686	sales@rechemscience.com	China	2971	58
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@yongstandards.com	China	9995	55
Guangzhou Dreampharm Biotechnology Co., Ltd.	020-36607679; 13502246435	3008233746@qq.com	China	9968	12
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14320	58
Jinan blalong chemical co. LTD	2710913286@qq.com	1513643261@qq.com	China	14227	58
Cato Research Chemicals Inc.	+86-020-81960175-877 4000-868-328;4000-868-328	tianwen.zhan@cato-chem.com	United States	10384	58

Supplier	Advantage
BJBXSW	58
Quality Control Solutions Ltd.	56
Shanghai Kewel Chemical Co., Ltd.	50
Shanghai Haozhixiang Biotechnology Co., Ltd	55
Shanghai Rechem science Co., Ltd.	58
Hubei Yangxin Medical Technology Co., Ltd.	55
Guangzhou Dreampharm Biotechnology Co., Ltd.	12
Standardpharm Co. Ltd.	58
Jinan blalong chemical co. LTD	58
Cato Research Chemicals Inc.	58

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7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide 7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide (Midazolam inte Midazolam Impurity 11 (E)-7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide 1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide 7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide 7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide 7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide MIDAZOLAM NITROMETHYLENE COMPOUND Midazolam Impurity 26 Midazolam Impurity 7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide 60656-76-0