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ent-idoxuridine

CAS No.
162239-35-2
Chemical Name:
ent-idoxuridine
Synonyms
ent-Idoxuridine;Idoxuridine Impurity 1;Idoxuridine Enantiomer;2'-Deoxy-L-5-iodouridine;5-Iodo-2'-deoxy-L-uridine;1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-iodo-
CBNumber:
CB11269894
Molecular Formula:
C9H11IN2O5
Molecular Weight:
354.1
MDL Number:
MOL File:
162239-35-2.mol
MSDS File:
SDS
Last updated:2024-09-12 10:40:36
Product description Number Pack Size Price
ent-idoxuridine 296103 2mg $446
ent-Idoxuridine 014727 5mg $446
ent-Idoxuridine I205755 50mg $1230
ent-idoxuridine NE16541 50mg $1529
ent-idoxuridine NE16541 2mg $139.9
More product size

ent-idoxuridine Properties

InChI InChI=1/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5?,6-,7-/s3
InChIKey XQFRJNBWHJMXHO-WGPDPFDPNA-N
SMILES N1C(=O)C(I)=CN([C@@H]2CC(O)[C@H](CO)O2)C1=O |&1:7,11,r|

ent-idoxuridine price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 296103 ent-idoxuridine 162239-35-2 2mg $446 2021-12-16 Buy
Usbiological 014727 ent-Idoxuridine 162239-35-2 5mg $446 2021-12-16 Buy
TRC I205755 ent-Idoxuridine 162239-35-2 50mg $1230 2021-12-16 Buy
Biosynth Carbosynth NE16541 ent-idoxuridine 162239-35-2 50mg $1529 2021-12-16 Buy
Biosynth Carbosynth NE16541 ent-idoxuridine 162239-35-2 2mg $139.9 2021-12-16 Buy
Product number Packaging Price Buy
296103 2mg $446 Buy
014727 5mg $446 Buy
I205755 50mg $1230 Buy
NE16541 50mg $1529 Buy
NE16541 2mg $139.9 Buy

ent-idoxuridine Chemical Properties,Uses,Production

Description

Ent-Idoxuridine, also known as 5-iodo-2'-deoxyuridine, is a cytosolic DNA synthesis inhibitor that acts by blocking the conversion of deoxycytidine to deoxyadenosine through the inhibition of the enzyme deoxycytidine kinase. As an enantiomer of idoxuridine, it shares the exact mechanism of action. Notably, ent-idoxuridine is resistant to exonucleases and has demonstrated effectiveness in treating immunodeficiency caused by HIV.

Uses

The enantiomer of Idoxuridine (I205750). Antitumor nucleoside enantiomer thymidine kinase used as potential antiviral agents.

ent-idoxuridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-iodo- ent-Idoxuridine 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione 2'-Deoxy-L-5-iodouridine 5-Iodo-2'-deoxy-L-uridine Idoxuridine Enantiomer Idoxuridine Impurity 1 162239-35-2 Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals