ChemicalBook >> CAS DataBase List >>Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]-

Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]-

Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]- structure

CAS No.: 2378837-56-8

Chemical Name:: Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]-

Synonyms: Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]-

CBNumber:: CB112741196

Molecular Formula:: C78H119FN12O34

Molecular Weight:: 1787.84

MDL Number:

MOL File:: 2378837-56-8.mol

Last updated:2025-04-18 09:51:36

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Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]- Properties

Density	1.48±0.1 g/cm3(Predicted)
pka	7.05±0.20(Predicted)

Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]- Chemical Properties, Uses, Production

Uses

M-MoDE-A (2) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR).

References

[1] Caianiello DF, et al. Bifunctional small molecules that mediate the degradation of extracellular proteins. Nat Chem Biol. 2021 Sep;17(9):947-953. DOI:10.1038/s41589-021-00851-1

Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

2378837-56-8 (Butanamide, N-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,4-bis[14-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxo-2,9,12-trioxa-6-azatetradec-1-yl]-2,9-dioxo-6,13,16-trioxa-3,10-diazaoctadec-1-yl]-4-[[2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-6-quinolinyl]oxy]-) Related Search:

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-, 2,2,2-trifluoroacetate (1:1) Tri-GalNAc(OAc)3-Perfluorophenyl 4,13,16,19-Tetraoxa-7,10-diazaheneicosanamide, N-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]-6,6-bis[[3-[[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]amino]-3-oxopropoxy]methyl]-21-[(2,4-dinitrophenyl)amino]-8,11-dioxo- Tri-GalNAc-DBCO NA

tri-GalNAc-C10-CONH-Maleimide

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