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Methyl vanillate

Methyl vanillate structure

CAS No.: 3943-74-6

Chemical Name:: Methyl vanillate

Synonyms: METHYL 4-HYDROXY-3-METHOXYBENZOATE;62-65oC;METHYL VANILLATE;Methylevanillate;MethylVanillate>TIMTEC-BB SBB008281;RARECHEM AL BF 0101;Eugenol Impurity 26;Vanillic acid methyl;Methyl vanillate 99%

CBNumber:: CB1138142

Molecular Formula:: C9H10O4

Molecular Weight:: 182.17

MDL Number:: MFCD00008438

MOL File:: 3943-74-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:08:54

Product description	Number	Pack Size	Price
Methyl vanillate 99%	138126	25g	$137
Methyl vanillate 99%	138126	100g	$522
Methyl Vanillate >98.0%(GC)	M1738	5g	$31
Methyl Vanillate >98.0%(GC)	M1738	25g	$100
Methyl Vanillate	TRC-M338490-5G	5g	$122
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Methyl vanillate Properties

Melting point	64-67 °C (lit.)
Boiling point	285-287 °C (lit.)
Density	1.2481 (rough estimate)
refractive index	1.4500 (estimate)
FLAVIS Number	09.799 \| Methyl vanillate
Flash point	285-287°C
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in chloroform and methanol.
form	Powder and Granules
pka	8.36±0.18(Predicted)
color	Pale yellow to beige
Odor	at 100.00 %. warm spicy vanilla guaiacol phenolic carnation
Odor Type	vanilla
biological source	synthetic
BRN	1369113
Cosmetics Ingredients Functions	PERFUMING
InChI	1S/C9H10O4/c1-12-8-5-6(9(11)13-2)3-4-7(8)10/h3-5,10H,1-2H3
InChIKey	BVWTXUYLKBHMOX-UHFFFAOYSA-N
SMILES	COC(=O)c1ccc(O)c(OC)c1
LogP	2.231 (est)
CAS DataBase Reference	3943-74-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	2HXG8QSO3D
NIST Chemistry Reference	Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester(3943-74-6)
EPA Substance Registry System	Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester (3943-74-6)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

RTECS

DH2430000

TSCA

TSCA listed

HS Code

29189900

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

Methyl vanillate price More Price(68)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	138126	Methyl vanillate 99%	3943-74-6	25g	$137	2026-04-30	Buy
Sigma-Aldrich	138126	Methyl vanillate 99%	3943-74-6	100g	$522	2026-04-30	Buy
TCI Chemical	M1738	Methyl Vanillate >98.0%(GC)	3943-74-6	5g	$31	2026-04-30	Buy
TCI Chemical	M1738	Methyl Vanillate >98.0%(GC)	3943-74-6	25g	$100	2026-04-30	Buy
TRC	TRC-M338490-5G	Methyl Vanillate	3943-74-6	5g	$122	2026-06-03	Buy

Product number	Packaging	Price	Buy
138126	25g	$137	Buy
138126	100g	$522	Buy
M1738	5g	$31	Buy
M1738	25g	$100	Buy
TRC-M338490-5G	5g	$122	Buy

Methyl vanillate Chemical Properties,Uses,Production

Chemical Properties

pale yellow to beige powder and granules

Uses

Methyl Vanillate maintains antimicrobial properties due to the phenylpropanoid moiety in the structure.

Uses

Methyl vanillate is used to investigate the volatile compounds of heather honeys from Calluna vulgaris and Erica arborea.

Definition

ChEBI: Methyl vanillate is a benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite. It is a benzoate ester, a member of phenols and an aromatic ether. It is functionally related to a vanillic acid.

General Description

Methyl vanillate is a volatile compound present in cloudberries (Rubus Chamaemorus.). Methyl vanillate can be synthesized from vanillic acid. Methyl vanillate has been identified in foods such as cow's milk and beer.

Biological Activity

Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

References

[1] PU-HYEON CHA. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice.[J]. PLoS ONE, 2014: e85546. DOI:10.1371/journal.pone.0085546.
[2] ADRIANO DE SOUZA PESSOA . The dimerization of methyl vanillate improves its effect against breast cancer cells via pro-oxidant effect[J]. Chemico-Biological Interactions, 2022, 361: Article 109962. DOI:10.1016/j.cbi.2022.109962.
[3] CHRONG-SHYUA CHU P. D R C Liao. A formal synthesis of (+/-)-reserpine from methyl vanillate[J]. Chemical Communications, 1996, 1 1: 1537-1538. DOI:10.1039/CC9960001537.
[4] JUAN TIAN. Ethyl acetate as a co-solvent and sacrificial ester in the aluminum triiodide promoted chemoselective demethylation of methyl vanillate[J]. Tetrahedron Letters, 2017, 58 36: Pages 3522-3524. DOI:10.1016/j.tetlet.2017.07.089.

Methyl vanillate Preparation Products And Raw materials

Raw materials

Syringaldehyde Methyl syringate Methanol Vanillin

Preparation Products

Methyl 3,4-dihydroxybenzoate Methyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoate AGMWEOLWLPKJFM-UHFFFAOYSA-N UNC-0642 Methyl 4-chloro-3-methoxy-5-nitrobenzenecarboxylate

4-BENZYLOXY-5-METHOXY-2-NITRO-BENZOIC ACID 4-Chloro-6-methoxy-7-(3-piperidin-1-yl-propoxy)-quinazoline Protocatechuic acid Benzoic acid, 3-methoxy-4-propoxy-, methyl ester

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Methyl vanillate Suppliers

Global( 434)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Huanfu Industrial Co.，（Shanghai）Ltd.	+86-18001856580	2415195517@qq.com	China	43	58
Shandong Liteng Biotechnology Co. , Ltd.	+86-18663721413 +86-15552573001	rosy@litengpharm.com	China	3280	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5229	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	+15184799099	lbaochemicals@gmail.com	China	670	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58

Supplier	Advantage
Huanfu Industrial Co.，（Shanghai）Ltd.	58
Shandong Liteng Biotechnology Co. , Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Anqing Chico Pharmaceutical Co., Ltd.	58

View Lastest Price from Methyl vanillate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-28	Methyl vanillate 3943-74-6	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2026-05-18	Methyl vanillate 3943-74-6		1kg	98%		Hefei Lbao Physical & Chemical Science Co.,Ltd
2026-03-20	Methyl vanillate 3943-74-6	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

Methyl vanillate
3943-74-6
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

Methyl vanillate
3943-74-6
$0.00
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

Methyl vanillate
3943-74-6
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

Methyl vanillate Spectrum

Methyl vanillate(3943-74-6)MS Methyl vanillate(3943-74-6)¹HNMR Methyl vanillate(3943-74-6)¹³CNMR Methyl vanillate(3943-74-6)IR1 Methyl vanillate(3943-74-6)IR2 Methyl vanillate(3943-74-6)Raman

3943-74-6(Methyl vanillate)Related Search:

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