perlapine
- CAS No.
- 1977-11-3
- Chemical Name:
- perlapine
- Synonyms
- HF 2333;Hypnodin;AW 14-2333;6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepin;6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine;11H-Dibenz[b,e]azepine, 6-(4-methyl-1-piperazinyl)-;6-(4-methylpiperazin-1-yl)-11H-benzo[c][1]benzazepine
- CBNumber:
- CB11388928
- Molecular Formula:
- C19H21N3
- Molecular Weight:
- 291.39
- MDL Number:
- MFCD00867539
- MOL File:
- 1977-11-3.mol
| Melting point | 136-138° |
|---|---|
| Boiling point | 423.4°C (rough estimate) |
| Density | 1.0521 (rough estimate) |
| refractive index | 1.6080 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml |
| pka | 8.00±0.20(Predicted) |
| form | A crystalline solid |
| color | White |
| FDA UNII | 4N8UJJ27IM |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Toxicity | LD50 in male, female mice, rats (mg/kg): 61, 61, 60, 66 i.v.; 250, 300, 480, 420 s.c., 270, 280, 660, 720 orally (Yokotani) | |||||||||
| NFPA 704 |
|
perlapine price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17756 | Perlapine ≥98% | 1977-11-3 | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 17756 | Perlapine ≥98% | 1977-11-3 | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 17756 | Perlapine ≥98% | 1977-11-3 | 10mg | $172 | 2024-03-01 | Buy |
| TRC | N900420 | Perlapine | 1977-11-3 | 10mg | $135 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003796 | PERLAPINE 95.00% | 1977-11-3 | 20MG | $238 | 2021-12-16 | Buy |
perlapine Chemical Properties,Uses,Production
Uses
Perlapine is an atypical neuroleptic that blocks dopamine and serotonin (5-HT) receptors (Kis = 60, 30, and 30 nM for D2, D4, and 5-HT2A, respectively). Perlapine is also an agonist for hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor that activates neuronal firing. Perlapine displays >10,000-fold selectivity for hM3Dq over hM3.
Uses
Perlapine exhibits antipsychotic activity and blocks dopamine and serotonin receptors. Perlapine is also a novel agonist of hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD).
Definition
ChEBI: Perlapine is an organic molecular entity.
storage
Room temperature
perlapine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44813 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24863 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
