N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- CAS No.
- 103878-83-7
- Chemical Name:
- N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- Synonyms
- TeMpiuM;Ro 19-6327/001;JMFKTFLARGGXCC-UHFFFAOYSA-N;N-(2-Aminoethyl)-5-chlor-2-pyridincarbox;Lazabemide hydrochloride , Lazabemide HCl;N-(2-aminoethyl)-5-chloropicolinamide hydrochloride;N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride;ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
- CBNumber:
- CB11448718
- Molecular Formula:
- C8H10ClN3O.HCl
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 103878-83-7.mol
- MSDS File:
- SDS
Melting point | 193-195° |
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storage temp. | Desiccate at RT |
solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
form | Powder |
pka | 8.9(at 25℃) |
FDA UNII | PI150J9ZX1 |
SAFETY
Risk and Safety Statements
Toxicity | LD50 orally in mice: 1000-2000 mg/kg (Imhof, Kyburz, 1986) |
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | L215258 | LazabemideHydrochloride | 103878-83-7 | 50mg | $305 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003133 | LAZABEMIDE HYDROCHLORIDE 95.00% | 103878-83-7 | 10MG | $648.83 | 2021-12-16 | Buy |
ApexBio Technology | B7064 | Lazabemidehydrochloride | 103878-83-7 | 50mg | $795 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003133 | LAZABEMIDE HYDROCHLORIDE 95.00% | 103878-83-7 | 50MG | $976.27 | 2021-12-16 | Buy |
ApexBio Technology | B7064 | Lazabemidehydrochloride | 103878-83-7 | 10mg | $196 | 2021-12-16 | Buy |
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Chemical Properties,Uses,Production
Uses
Treatment of Alzheimer’s disease.
Uses
Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.
Definition
ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.
brand name
Tempium (Hoffmann-LaRoche).
Biological Activity
Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).
storage
Desiccate at RT
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Preparation Products And Raw materials
Raw materials
Preparation Products
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 | |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12335 | 58 |
View Lastest Price from N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-09 | Lazabemide hydrochloride
103878-83-7
|
US $50.00-116.00 / mg | 98.65% | 10g | TargetMol Chemicals Inc. |
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- Lazabemide hydrochloride
103878-83-7
- US $50.00-116.00 / mg
- 98.65%
- TargetMol Chemicals Inc.