ChemicalBook >> CAS DataBase List >>1H-INDAZOLE-5-CARBONITRILE

1H-INDAZOLE-5-CARBONITRILE

CAS No.
74626-47-4
Chemical Name:
1H-INDAZOLE-5-CARBONITRILE
Synonyms
5-Cyanoindazole;5-Cyano-1H-indazole;Indazole-5-carbonitrile;1H-INDAZOLE-5-CARBONITRILE;1H-Indazole-5-carbonitrile(9CI);1H-Indazole-5-carbonitrile ,97%
CBNumber:
CB1150283
Molecular Formula:
C8H5N3
Molecular Weight:
143.15
MDL Number:
MFCD04973397
MOL File:
74626-47-4.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:54
Product description Number Pack Size Price
1H-Indazole-5-carbonitrile I509063 100mg $60
1H-Indazole-5-carbonitrile 3H37-1-N3 250mg $29
1H-Indazole-5-carbonitrile 98% 057941 1g $220
1H-Indazole-5-carbonitrile 98% 057941 5g $430
5-CyanoIndazole V2200 10g $636
More product size

1H-INDAZOLE-5-CARBONITRILE Properties

Boiling point 370.3±15.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form Solid
pka 12.19±0.40(Predicted)
Appearance Pink to red Solid
CAS DataBase Reference 74626-47-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  29339900

1H-INDAZOLE-5-CARBONITRILE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I509063 1H-Indazole-5-carbonitrile 74626-47-4 100mg $60 2021-12-16 Buy
SynQuest Laboratories 3H37-1-N3 1H-Indazole-5-carbonitrile 74626-47-4 250mg $29 2021-12-16 Buy
Matrix Scientific 057941 1H-Indazole-5-carbonitrile 98% 74626-47-4 1g $220 2021-12-16 Buy
Matrix Scientific 057941 1H-Indazole-5-carbonitrile 98% 74626-47-4 5g $430 2021-12-16 Buy
AK Scientific V2200 5-CyanoIndazole 74626-47-4 10g $636 2021-12-16 Buy
Product number Packaging Price Buy
I509063 100mg $60 Buy
3H37-1-N3 250mg $29 Buy
057941 1g $220 Buy
057941 5g $430 Buy
V2200 10g $636 Buy

1H-INDAZOLE-5-CARBONITRILE Chemical Properties,Uses,Production

Chemical Properties

White solid

Synthesis

5-CYANO-2-FLUOROBENZALDEHYDE

146137-79-3

1H-INDAZOLE-5-CARBONITRILE

74626-47-4

General procedure for the synthesis of indazole-5-carbonitrile from 4-fluoro-3-formylbenzonitrile: 4-fluoro-3-formylbenzonitrile (25 g, 16.78 mmol) was dissolved in 100 mL of 85% hydrazine hydrate. The reaction mixture was stirred at room temperature for 24 hours. After completion of the reaction, the product was purified by column chromatography to afford 1H-indazole-5-carbonitrile (2.1 g, 87% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI): 1H NMR δ 13.60 (s, 1H), 8.42 (s, 1H), 8.27 (s, 1H), 7.73 (d, J = 8.6 Hz, 1H), 7.67 (d, J = 8.6 Hz, 1H); MS m/z (ESI): 144 [M + H]+.

References

[1] Patent: EP3205650, 2017, A1. Location in patent: Paragraph 0106; 0345
[2] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 15, p. 4191 - 4195
[3] Synthetic Communications, 1997, vol. 27, # 7, p. 1199 - 1207
[4] Patent: US6376499, 2002, B1
[5] Patent: US6610692, 2003, B1

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View Lastest Price from 1H-INDAZOLE-5-CARBONITRILE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-INDAZOLE-5-CARBONITRILE pictures 2020-01-13 1H-INDAZOLE-5-CARBONITRILE
74626-47-4
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co
4-keto-L-proline hydrobromide pictures 2020-01-13 4-keto-L-proline hydrobromide
75776-67-9
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

1H-INDAZOLE-5-CARBONITRILE Spectrum

1H-Indazole-5-carbonitrile ,97% 5-Cyanoindazole Indazole-5-carbonitrile 5-Cyano-1H-indazole 1H-INDAZOLE-5-CARBONITRILE 1H-Indazole-5-carbonitrile(9CI) 74626-47-4 pharmacetical Building Blocks Indazole NITRILE